Results 111 to 120 of about 26,058,575 (297)
IGOR and Computer Assisted Innovation in Chemistry
CHIMIA, 1985 IGOR (Interactive Generation of Organic Reactions) is the first general-purpose, artificialintelligence-type computer program for generating graphic representations of unprecedented chemistry.
Johannes Bauer +3 more
doaj +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Attention-LSTM based prediction model for aircraft 4-D trajectory. [PDF]
Sci Rep, 2022 Jia P, Chen H, Zhang L, Han D.
europepmc +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Application of 4-D ultrasound-derived regional strain and proteomics analysis in Nkx2-5-deficient male mice. [PDF]
Am J Physiol Heart Circ Physiol, 2023 Damen FW +5 more
europepmc +1 more source
Large-scale analysis of human heavy chain V(D)J recombination patterns-4
, 2011 Gene sets.Copyright information:Taken from "Large-scale analysis of human heavy chain V(D)J recombination patterns"http://www.immunome-research.com/content/4/1/3Immunome Research 2008;4():3-3.Published online 27 Feb 2008PMCID:PMC2275228.
Joseph M Volpe (89200) +1 more
core +1 more source
Vitamin D Testing Practices in Collegiate Cross Country and Track and Field Athletes [PDF]
, 2021 Vitamin D insufficiency and deficiency has become problematic within the global population. Low levels of Vitamin D may have significant impacts on bone health and the musculoskeletal system, key factors in athletic performance.
Ross, Allison
core
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Segmentation of beating embryonic heart structures from 4-D OCT images using deep learning. [PDF]
Biomed Opt Express, 2023 Ling S +6 more
europepmc +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source