Results 131 to 140 of about 26,058,575 (297)

Tubular proteinuria and vitamin D deficiency in sickle cell disease [PDF]

open access: yes, 2019
Kidney disease is a significant complication of sickle cell disease (SCD) with great public health concern, causing over 18% of total patient mortality. Proximal tubule (PT) dysfunction, including tubular proteinuria, is a common early symptom of kidney ...
Gliozzi, Megan
core  

Near-field terahertz time-domain spectroscopy for in-line electrical metrology of semiconductor integration processes for memory

open access: yesCommunications Engineering
Monitoring electrical properties in semiconductor integration processes is crucial in identifying electrical defects that determine the reliability and performance of metal oxide semiconductor field-effect transistors. A non-destructive in-line metrology
Sunhong Jun   +15 more
doaj   +1 more source

KRAS/NRAS Gene Mutations and the Efficacy of Bortezomib-Based Triplet Induction Therapy in Patients with Newly Diagnosed Multiple Myeloma

open access: yesКлиническая онкогематология
AIM. To identify the KRAS and NRAS gene mutations in patients with newly diagnosed multiple myeloma (ММ) and to classify them according to the depth of antitumor response to bortezomib-based triplet induction therapy. MATERIALS & METHODS.
Anna Mikhailovna Sergeeva   +6 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Analysis of Upper Airway Flow Dynamics in Robin Sequence Infants Using 4-D Computed Tomography and Computational Fluid Dynamics. [PDF]

open access: yesAnn Biomed Eng, 2023
Barbour M   +6 more
europepmc   +1 more source

YOLO-Faster: An efficient remote sensing object detection method based on AMFFN

open access: yesScience Progress
As a pivotal task within computer vision, object detection finds application across a diverse spectrum of industrial scenarios. The advent of deep learning technologies has significantly elevated the accuracy of object detectors designed for general ...
Yicheng Tong   +9 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Vitamin D: to test or not to test

open access: yes, 2014
Vitamin D deficiency has recently been linked to many chronic diseases such as MS (multiple sclerosis), cancer, rheumatoid arthritis, and diabetes. It has been a topic of debate among healthcare providers on whether or not it is beneficial to test and ...
Gill, Danielle
core  

Lattice-Free Simplexes in Dimension 4 [PDF]

open access: yes, 2011
We use a numerical approach to discover lattice free simplexes in dimension 4 with width at least 3. We follow the methodologies of Mori, Morrison, and Morrison and use a theoretical result proven by Barille, Bernardi, Borisov, and Kantor to conjecture a
Perriello, Andrew
core  

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