Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Adding a new dimension: Multi-level structure and organization of mixed-species Pseudomonas aeruginosa and Staphylococcus aureus biofilms in a 4-D wound microenvironment. [PDF]
Biofilm, 2022 Dhekane R, Mhade S, Kaushik KS.
europepmc +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Lattice-Free Simplexes in Dimension 4 [PDF]
, 2011 We use a numerical approach to discover lattice free simplexes in dimension 4 with width at least 3. We follow the methodologies of Mori, Morrison, and Morrison and use a theoretical result proven by Barille, Bernardi, Borisov, and Kantor to conjecture a
Perriello, Andrew
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Evaluation of pulmonary blood flow in bilateral bidirectional Glenn shunts: value of 4-D flow cardiac magnetic resonance in the evaluation of pulmonary artery confluence stenosis. [PDF]
Clin Case Rep, 2022 Al Kindi F +3 more
europepmc +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
, 1986 ALADI. Comité de Coordinación y Negociaciones.
ALADI. Comité de Coordinación y Negociaciones. Subcomité 4: Sistema de Apoyo a los Países de Menor Desarrollo Económico Relativo
core +1 more source
Demographic and psychosocial correlates of measurement error and reactivity bias in a 4-d image-based mobile food record among adults with overweight and obesity. [PDF]
Br J Nutr, 2023 Whitton C +8 more
europepmc +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Vitamin D, Tissue Resistance, Bone Mineral Density and Breast Cancer Risk [PDF]
, 2009 Etiologic factors such as vitamin D and estrogen are potentially related to breast cancer development, although details of their mechanisms are not completely understood. We prospectively investigated correlates of breast cancer risk among postmenopausal
Albano, Jessica
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