Results 101 to 110 of about 32,447,375 (296)

4-D Generative Model for PET/MRI Reconstruction [PDF]

open access: yes, 2011
We introduce a 4-dimensional joint generative probabilistic model for estimation of activity in a PET/MRI imaging system. The model is based on a mixture of Gaussians, relating time dependent activity and MRI image intensity to a hidden static variable, allowing one to estimate jointly activity, the parameters that capture the interdependence of the ...
Stefano Pedemonte   +4 more
openaire   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Document: Charles D. Drake

open access: yes, 1898
Extract from speech of Charles D. Drake, chairman of Committee of Seventy, delivered at St.
Drake, Charles D.
core  

The Prognostic Value of Minimal Residual Disease Assessed During the Remission Induction Stage in Acute Myeloid Leukemia Patients

open access: yesКлиническая онкогематология
BACKGROUND. The assessment of minimal residual disease (MRD) in acute myeloid leukemias (AML) is an important tool for predicting treatment outcomes, especially in patients with favorable and intermediate cytogenetic/molecular risk.
Irina Vladimirovna Galtseva   +10 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Vitamin D Testing Practices in Collegiate Cross Country and Track and Field Athletes [PDF]

open access: yes, 2021
Vitamin D insufficiency and deficiency has become problematic within the global population. Low levels of Vitamin D may have significant impacts on bone health and the musculoskeletal system, key factors in athletic performance.
Ross, Allison
core  

Magnetic Resonance Imaging of Bone Marrow and its Results as a Criterion for Administration of Maintenance Therapy After Auto-HSCT in Multiple Myeloma Patients

open access: yesКлиническая онкогематология, 2018
Aim. To evaluate the efficacy of maintenance therapy in multiple myeloma (MM) patients after autologous hematopoietic stem cell transplantation (auto-HSCT) based on the results of MRI of bone marrow. Materials & Methods.
Maksim Valer’evich Solov’ev   +6 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Concise Synthesis of (+)-2-C-Methyl-d-erythritol-4-phosphate

open access: yes, 2016
Concise Synthesis of (+)-2-C-Methyl-d-erythritol-4 ...
Angelo Fontana (404567)
core   +1 more source

Home - About - Disclaimer - Privacy