FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Concise Synthesis of (+)-2-C-Methyl-d-erythritol-4-phosphate
, 2016 Concise Synthesis of (+)-2-C-Methyl-d-erythritol-4 ...
Angelo Fontana (404567)
core +1 more source
3-D self-assembly of flower-like particles via microwave irradiation for water treatment [PDF]
, 2012 Three-dimensional (3-D) flower-like shape (FLS) Fe 3O 4 and Fe particles were successfully synthesized using FLS precursor particles that are prepared through a facile microwave-assisted reaction.
Jung, Y +5 more
core +1 more source
Клиническая онкогематологияBACKGROUND. The assessment of minimal residual disease (MRD) in acute myeloid leukemias (AML) is an important tool for predicting treatment outcomes, especially in patients with favorable and intermediate cytogenetic/molecular risk.
Irina Vladimirovna Galtseva +10 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Genetic association between APOE*4 and neuropsychiatric symptoms in patients with probable Alzheimer's disease is dependent on the psychosis phenotype [PDF]
, 2012 Background: Neuropsychiatric symptoms such as psychosis are prevalent in patients with probable Alzheimer's disease (AD) and are associated with increased morbidity and mortality.
Lopez, OL +9 more
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Guided block matching and 4-D transform domain filter projection denoising method for dynamic PET image reconstruction. [PDF]
EJNMMI Phys, 2023 Xin L, Zhuo W, Liu H, Xie T.
europepmc +1 more source
A prospective randomized trial of tacrolimus and prednisone versus tacrolimus, prednisone and mycophenolate mofetil in primary adult liver transplantation: A single center report [PDF]
, 2001 Background. Tacrolimus (TAC) and mycophenolate mofetil (MMF) are currently approved immunosuppressants for prevention of rejection in liver transplantation (LTx).
Dodson, F +8 more
core +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source