Results 231 to 240 of about 19,839 (264)

Persistence to antihypertensive drug classes in uncomplicated hypertension: a nationwide Swedish cohort study. [PDF]

open access: yesEClinicalMedicine
Laurell K   +7 more
europepmc   +1 more source

脳血管障害例に対する1, 4-Dihydropyridine誘導体YC-93の臨床使用経験

open access: green, 1979
Jyoji Handa   +4 more
openalex   +1 more source

Diversified Synthetic Pathway of 1, 4-Dihydropyridines: A Class of Pharmacologically Important Molecules

Mini-Reviews in Medicinal Chemistry, 2021
The current review discusses the different synthetic pathways for one of the most important and interesting heterocyclic ring systems, 1,4-dihydropyridine. This cyclic system depicts diverse pharmacological action on several receptors, channels, and enzymes. Dihydropyridine moiety plays an important role in several calcium-channel blockers. Moreover,
Shubham, Khot   +2 more
openaire   +3 more sources

1, 4‐Dihydropyridine mit Etacrynsäure‐Partialstruktur

Archiv der Pharmazie, 1992
AbstractAusgehend von dem Acetophenon 3 werden über die Nitrobenzyliden‐Verbindungen 4 und 5 die 1,4‐Dihydropyridine (DHP) 6 und 7 mit einem Dichlorphenoxyessigsäure‐Substituenten hergestellt. Die DHP werden zu den Pyridinen 8 und 9 oxidiert. Bei der Bestrahlung des DHP 6a entsteht die cyclische Hydroxamsäure 10.
Klaus Görlitzer, Wolfgang Düwel
openaire   +1 more source

N‐alkylation of 1, 4‐dihydropyridine derivatives

Bulletin des Sociétés Chimiques Belges, 1973
AbstractA series of 1‐alkyl‐2, 6‐dimethyl‐3, 5‐diethoxycarbonyl‐4‐aryl‐1, 4‐dihydropyridines have been synthesised by the reaction of the corresponding 1, 4‐dihydro‐pyridines with consecutively sodium hydride and alkyl halides.
R. A. Dommisse, F. C. Alderweireldt
openaire   +1 more source

Synthesis of 2,3-dihydrobenzofuran-3-spiro-4′-dihydropyridines

Tetrahedron Letters, 1981
Abstract 2,3-Dihydrobenzofuran-3-spiro-4′-dihydropyridines are readily available via intramolecular addition of enolates to pyridinium ions.
Dwight D. Weller, Glenn R. Luellen
openaire   +1 more source

Synthese et reaction de diacyl-1,4 alkyl-4 dihydropyridines

Tetrahedron, 1973
Resume L'action du zinc et des anhydrides acetique, propionique et butyrique sur des pyridines substituees en C-4 donne des diacyl-1,4 alkyl-4 dihydropyridines, qui peuvent egalement etre obtenues par reaction radicalaire. L'acetyl-1 methylene-4 methyl-5 dihydro-4,5 azepine 24 a ete preparee par solvolyse du tosylate 23 , derivant de la diacetyl-1,
P.M. Atlani, J.F. Biellmann, J. Moron
openaire   +1 more source

ChemInform Abstract: SYNTHESIS OF 2,3‐DIHYDROBENZOFURAN‐3‐SPIRO‐4′‐DIHYDROPYRIDINES

Chemischer Informationsdienst, 1982
AbstractBei der Kondensation von Salicylaldehydmethylether (I) mit 2‐Acetyl‐furan (II) erhält man unter alkalischen Bedingungen das Diketon (III), das durch weitere Kondensation mit Hydroxylamin, anschließende Permanganatoxidation und Thermolyse über das Pyridin (IVa) und die Dicarbonsäure (IVb) zum Decarboxylierungsprodukt (IVc) führt.
D. D. WELLER, G. R. LUELLEN
openaire   +1 more source

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