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1, 3, 4-Oxadiazole: A Versatile Compound With Potent Analgesic Activity

Oxadiazole is a heterocyclic ring with 5 members that has 1 oxygen atom, 2 nitrogen atoms, 2 double bonds, and 2 carbons. In furan, they are created by placing two methylene groups (=CH) for two nitrogen (-N=) atoms. The aromaticity was reduced by the substitution of these groups. There were four different isomer of oxadiazole that were identified: 1,3,
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5‐(1‐Alkenyl)‐1, 3, 4‐oxadiazol‐2(3H)‐one

Helvetica Chimica Acta, 1974
Abstract3‐(2‐alkenoyl)‐thiocarbazic acid O‐methyl esters 1 are desulfurated by bromine and the unknown intermediates are transformed by alkali to 5‐(1‐alkenyl)‐1, 3, 4‐oxadiazol‐2(3H)‐ones (2). This type of oxadiazolone substitution is not realizable by the common ring closure of hydrazides with phosgene due to pyrazolidinone ring closure of ...
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Microwave spectra of isotopic 1, 3, 4-oxadiazoles

Journal of Molecular Structure, 1972
Lise Nygaard   +5 more
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Microwave reactions of 2, 5-bis-trifluoromethyl-1, 3, 4-oxadiazole with norbornenes

2009
The reactions of 2, 5-bis-trifluoromethyl-1, 3, 4- oxadiazole 2 with norbornenes [1] under microwave conditions were investigated. MW reactions enabled the reaction times and temperatures to be significantly reduced, as compared to classical thermal reactions.
Margetić, Davor   +2 more
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Aromatic poly(amide‐hydrazides) and poly(amide‐1,3‐4‐oxadiazoles)

Journal of Polymer Science Part B: Polymer Letters, 1967
Bill M. Culbertson, Rosemary Murphy
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The synthesis of 1 : 2 : 4-oxadiazoles

Journal of the Chemical Society (Resumed), 1954
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Theoretical study of synthesis and pharmaceutical activity of 1, 3, 4-oxadiazole derivatives

International Journal of Pharmaceutical and Clinical Research, 2022
Muntaha Yaseen Hayal   +2 more
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A Review On: Antifungal And Antibacterial Activity Of 1, 3, 4-Oxadiazole Derivatives

1,3,4-Oxadiazoles are five-membered heterocyclic compounds containing two nitrogen atoms and one oxygen atom. These versatile molecules exhibit a range of biological effects, including antibacterial, antifungal, and antiviral properties. Recent research has demonstrated that many 1,3,4-oxadiazole derivatives surpass the activity of existing antibiotics
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Synthesis of 1, 3, 4-Oxadiazole of NSAIDs and their Biological Properties

Asian Journal of Research in Chemistry, 2018
Shankaraiah Malthum   +2 more
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Synthesis of new 1 2 4 oxadiazoles

2015
Sakagami, HIROSHI   +4 more
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