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An Overview: 1, 3, 4- oxadiazole and its uses

Asian Journal of Research in Chemistry, 2021
Heterocyclic compounds show various potent biological activity. Every heterocyclic compound has different structure, different functional group and designed for different biological activities. Oxadiazole is one of those heterocyclic compounds possess various biological activity. The structure is simple contain carbon, nitrogen, oxygen, hydrogen.
Anuja S. Patil., Shrinivas K. Mohite
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[1, 2, 4]-Oxadiazoles: Synthesis and Biological Applications

Mini-Reviews in Medicinal Chemistry, 2014
In the present article synthesis and medicinal applications of [1, 2, 4] oxadiazoles are reviewed. The oxadiazoles have a wide range of applications such as Antitussive, Anti-inflammatory, Anaesthetic, Vasodilator, anthelmintic, antiallergic, antiplatelet effects in vitro, antithrombotic properties in vivo, etc.
Rajesh O, Bora   +3 more
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2, 5-Dialkyl-1, 3, 4-oxadiazoles

Chemistry of Heterocyclic Compounds, 1970
A single stage method has been developed for the preparation of 2, 5-dialky-1, 3, 4-oxadiazoles from aliphatic carboxylic acids, by boiling with hydrazine hydrochloride in phosphoryl chloride. A mechanism for the synthesis is suggested. The oxadiazoles are characterized, and the group refractivity of the 1, 3, 4-oxadiazole ring has been determined.
M. S. Skorobogatova   +2 more
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Synthesis of 1, 3, 4-Oxadiazole

Asian Journal of Research in Chemistry, 2017
Synthesis of 1, 3, 4-oxadiazole by the reaction of 2-propyl Benzo imidiazol-2-yl carbohydrazide and 1, 3, dihydro iso indo-2-yl acetic acid (Phthalyl Amino Acids) in presence of HCl and phosphoryl chloride. All the newly synthesized compounds were screened antibacterial activity which shows moderate to mild activity, and yield of the synthesized ...
Maqdoom Farooqui, Syed Nazimuddin
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Synthesis and study of poly (1, 3, 4-oxadiazoles)

Chemistry of Heterocyclic Compounds, 1967
Various conditions for synthesizing poly (1,3,4-oxadiazoles) from carboxylic acids, their hydrazides, and polyhydrazides, are investigated. Methods of cyclodehydration of polyhydrazides using phosphorus oxychloride, sulfuric acid, and certain other reagents are not of general utility for synthesizing poly (1,3,4-oxadiazoles).
A. P. Grekov   +2 more
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Poly(1, 3, 4-Oxadiazole-Amide)s Containing Pendent Phenoxy Groups

High Performance Polymers, 1996
A series of new poly(1, 3, 4-oxadiazole-amide)s have been synthesized by solution polycondensation of aromatic diamines containing preformed 1, 3, 4-oxadiazole rings with phenoxyterephthalic diacid chloride or by the reaction of the same diacid chloride with p-aminobenzhydrazide resulting in a polyhydrazide-amide which was cyclodehydrated to the ...
Corneliu Hamciuc   +2 more
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SYNTHESIS AND ANTIMICROBIAL ACTIVITIES OF SOME NEW 1, 3, 4-OXADIAZOLES

INDIAN DRUGS, 2012
Various 5-β-[(N-Benzenesulphonyl/tosyl)-4-(un) substituted anilino] ethyl-2-H/CH3/C6H5/-CH2C6H5/p-NO2C6H4-1,3,4-oxadiazoles (5a-d), 5--β-[(N-Benzenesulphonyl/tosyl)-4-(un)-substituted anilino] ethyl-2-(N,N-diethylamino/anilino/morpholino)-1, 3, 4-oxadiazoles (6a-r), 3--β-[(N-Benzenesulphonyl/tosyl)-4-(un) substituted anilino] ethyl-4-amino-5-mercapto-4(
S Desai, U. Laddi
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Synthesis of Some New 1, 3, 4-Oxadiazole, Pyrazole, and Pyrimidine Bearing Thienopyrazole Moieties

Current Organic Synthesis, 2020
Aim and Objective: According to the literature survey, pyrazole is a unique template that is associated with several biological activities. This article highlighted the research work of many researchers reported in the literature for synthesis and different pharmacological activities of the pyrazole nucleus.
Mohamed Ahmed Elian Sophy   +1 more
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