Results 101 to 110 of about 9,299,574 (208)

Collective synthesis of 4-hydroxy-2-pyridone alkaloids and their antiproliferation activities

, 2014
A collective synthesis of 4-hydroxy-2-pyridone alkaloids—specifically, pretenellin B, prebassianin B, farinosone A, militarione D, pyridovericin, and torrubiellone C—has been achieved.
Ma, Jimei, Ding, Feiqing, Liao, Hongze, Leow, Min Li, William, Ronny, Liu, Xue-Wei   +5 more
core   +1 more source

Synthesis of azo pyridone dyes

, 2011
Over 50% of all colorants which are used nowdays are azo dyes and pigments, and among them arylazo pyridone dyes (and pigments) have became of interest in last several decades due to the high molar extinction coefficient, and the medium to high light ...
Ušćumlić, Gordana, Valentić, Nataša, Ušćumlić Gordana S., Valentić Nataša V., Marinković Aleksandar D., Dusan Mijin, Marinković, Aleksandar, Natasa Valentic, Aleksandar Marinkovic, Gordana Uscumlic, Mijin, Dušan, Mijin Dušan Ž.   +11 more
core   +1 more source

4-(4-Chlorophenyl)-6-phenyl-2-(prop-2-yn-1-yloxy)nicotinonitrile

Molbank
We report an efficient and transition-metal-free protocol for the propargylation of 4-(4-chlorophenyl)-2-oxo-6-phenyl-1,2-dihydropyridine-3-carbonitrile using propargyl bromide in the presence of cesium carbonate in dimethylsulfoxide under mild ...
Diana Becerra, Diana Hurtado-Rodríguez, Juan-Carlos Castillo   +2 more
doaj   +1 more source

SYNTHESIS OF ?-PYRONEIMINE N-OXIDE A NOVEL NITRONE WITH ELECTRON RELEASING SUBSTITUENT [PDF]

Journal of Sciences, Islamic Republic of Iran, 1997
N-Oxidation of 1,4-dihydro-2,6-dimethyl-1- phenyliminopyridine (7) with several peracids was attempted. The main compound obtained was l-phenyl- 2,6-dimethyl-4-pyridone (8), instead of the expected N-oxide (2).
doaj  

Pyridone Annulation by 4 + 2 Coupling of Dienolates with Nitriles and Nitrile Equivalents. A Solution to the Acetonitrile Problem

, 2016
Pyridone Annulation by 4 + 2 Coupling of Dienolates with Nitriles and Nitrile Equivalents.
Scott McN. Sieburth (1538176), Yanping Chen (141488), Tindy Li (2662483)   +2 more
core   +1 more source

Unraveling the stereochemically rich 2-pyridone [4+4] photodimer

ARKIVOC, 2010
Peiling Chen, Patrick J. Carroll, Scott McN. Sieburth   +2 more
doaj   +1 more source

Time-restricted feeding ameliorates non-alcoholic fatty liver disease through modulating hepatic nicotinamide metabolism via gut microbiota remodeling

Gut Microbes
Non-alcoholic fatty liver disease (NAFLD) has emerged as a global health concern, lacking specific therapeutic strategies. Time-restricted feeding (TRF) regimen demonstrated beneficial effects in NAFLD; however, the underlying mechanisms remain unclear ...
Ruijia Feng, Wenchao Yang, Weiqi Feng, Xiuyi Huang, Meifeng Cen, Guiyan Peng, Wenrui Wu, Zhecun Wang, Yexiang Jing, Ting Long, Yunchong Liu, Zilun Li, Guangqi Chang, Kan Huang   +13 more
doaj   +1 more source

Solid-Phase Synthesis of Diverse Macrocycles By Regiospecific 2-Pyridone Formation: Scope and Applications

This study introduces a novel solid-phase macrocyclization method generating 2-pyridone rings. This method relies on the intramolecular condensation between secondary and tertiary dimethoxy-propionic amide (DMPA) units.
Thomas, Kodadek, Skander, Abboud
core   +1 more source

Thermal-Induced Dimerization Cyclization of Ethyl N-(Styrylcarbamoyl)acetates: Formation of 4-Hydroxy-2(1H)-pyridone-3- carboxamide Derivatives

, 2014
Thermal-induced dimerization cyclization of ethyl N-(styrylcarbamoyl)acetate derivatives has been investigated, leading to 4-hydroxy-2(1H)-pyridone-3-carboxamide derivatives with good yields in diphenyl ether on 200–210 °C.
Yun-xia Deng (547266), Sheng-Yin Zhao (547263), Jing Huang (41604), Zhi-Yu Shao (547267), Shao-Hua Cheng (547265), Bao-Shuo Liu (547264)   +5 more
core   +1 more source

New thiazole, thiophene and 2-pyridone compounds incorporating dimethylaniline moiety: synthesis, cytotoxicity, ADME and molecular docking studies

BMC Chemistry
Various sets of thiazole, thiophene, and 2-pyridone ring structures containing a dimethylaniline component were synthesized. Substituted thiazoles 2–3 and thiophenes 5–7 were produced by reacting thiocarbamoyl compound 4 with α-halogenated reagents in ...
Heba M. Metwally, Norhan M. Younis, Ehab Abdel-Latif, Ali El-Rayyes   +3 more
doaj   +1 more source