Results 91 to 100 of about 12,753,193 (203)

An unusual nicotinamide derivative, 4-pyridone-3-carboxamide ribonucleoside (4PYR), is a novel endothelial toxin and oncometabolite. [PDF]

Exp Mol Med, 2021
Mierzejewska P, Kunc M, Zabielska-Kaczorowska MA, Kutryb-Zajac B, Pelikant-Malecka I, Braczko A, Jablonska P, Romaszko P, Koszalka P, Szade J, Smolenski RT, Slominska EM.   +11 more
europepmc   +1 more source

Biofilm-specific uptake of a 4-pyridone-based iron chelator by Pseudomonas aeruginosa. [PDF]

Biometals, 2021
Houshmandyar S, Eggleston IM, Bolhuis A.
europepmc   +1 more source

The S-1/S-2 exciton interaction in 2-pyridone center dot 6-methyl-2-pyridone: Davydov splitting, vibronic coupling, and vibronic quenching

, 2011
The excitonic splitting between the S-1 and S-2 electronic states of the doubly hydrogen-bonded dimer 2-pyridone center dot 6-methyl-2-pyridone (2PY center dot 6M2PY) is studied in a supersonic jet, applying two-color resonant two-photon ionization (2C ...
Ottiger, P., Leutwyler, S., Heid, C. G., Philipp Ottiger, Leist, R., Cornelia G. Heid, Roman Leist, Samuel Leutwyler   +7 more
core   +1 more source

Examining the safety of nicotinamide for skin cancer prevention: Review of adverse events, metabolism, and toxic dosages

JAAD Reviews
Nicotinamide (niacinamide) supplementation for non-melanoma skin cancer prevention has sparked controversy over the past decade due to its inconsistent evidence of chemoprevention and its recently challenged safety profile.
Katie R. Xu, BA, Micah Belzberg, MD, Allison T. Vidimos, MD, RPh   +2 more
doaj   +1 more source

Toxicity of six plant extracts and two pyridone alkaloids from Ricinus communis against the malaria vector Anopheles gambiae

Parasites & Vectors, 2014
Background The African malaria vector, Anopheles gambiae s.s., is known to feed selectively on certain plants for sugar sources. However, the adaptive significance of this behaviour especially on how the extracts of such plants impact on the fitness of ...
Sabina Wangui Wachira, Sabar Omar, Julia Wanjiru Jacob, Martin Wahome, Hans T Alborn, David R Spring, Daniel K Masiga, Baldwyn Torto   +7 more
doaj   +1 more source

catena-Poly[[[bis(2-pyridone-κO)sodium]-di-μ-2-pyridone-κ⁴O:O] tetrafluoroborate]

, 2007
In the title compound, [Na(C5H5NO)(4)] BF4, each Na+ ion, lying on an inversion centre, is octahedrally coordinated by four bridging and two terminal pyridone ligands, creating a cationic coordination polymer chain with tetrafluoroborate anions occupying
Owen, Gareth R., Haddow, Mairi F.
core   +1 more source

The photochemical[2 + 2]cycloaddition to N-methoxycarbonyl-5,6-dihydro-4-pyridone

, 1989
The N-methoxycarbonyl-5,6-dihydro-4-pyridone (1) undergoes photochemical [2 + 2] cycloaddition with a series of differently substituted alkenes in high yield and with extremely high ...
Guerry, Philippe, Neier, Reinhard
core   +1 more source

Pyridone-based nucleotide analogues accepted for DNA biosynthesis

, 2017
Novel pyridone-based nucleotides were investigated for maintenance of DNA synthesis, carried on by representatives of different classes of polymerases. Five different nucleoside triphosphates of similar structure were addressed, demonstrating involvement
Bazilė Ravoitytė, Algirdas Mikalkėnas, Daiva Tauraitė, Saulius Serva   +3 more
core   +1 more source

Synthesis and antitumour activity of 4-hydroxy-2-pyridone derivatives

, 2000
4-hydroxy-2-pyridone derivatives 2 were prepared by reaction of 3-amino-3-dialkylaminopropenoates with bis(2,4,6-trichlorophenyl)malonate. These compounds were further reacted with a set of aldehydes to give bis(pyridyl)methanes 3 and 4.
ONNIS, VALENTINA, CONGIU, CENZO, Cocco MT   +2 more
core   +1 more source

Studies on 4-Pyrones and 4-Pyridones. I. The Preparation of 1-Aryl-3-hydroxy-4-pyridones and Related Compounds

Croatica Chemica Acta, 1962
By condensation rnf meconic acid, comenic acid, or comenic acid methyl ether with primary aromatic amines, 1-aryl-5-hydroxy-4- -pyridone-2-carboxylic acids, or their methyl ethers, were obtained with satisfactory yields. Decarboxylation of the acids yielded 1-aryl-3-hydroxy-4-pyridones or the corresponding 1-aryl-3- -methoxy-4-pyridones.
Hahn, V., Kukolja, S.
openaire   +2 more sources