Results 81 to 90 of about 12,753,193 (203)
, 2016 Novel highly emissive 2-pyridone-based compounds 3a,b and 4a–d were synthesized by a convenient one-pot method from 4-(dialkylamino)acetophenones (1a,b) and cyanoketene dithioacetal (2a) or sulfonyl ketene dithioacetals (2b,c), and their fluorescence ...
Wang, Bo-cheng; Tai, Chen-kuen; Wang, San-lang; Shih, Tzenge-lien; Wu, Kuen-da; Huang, Zhi-shuan; Tseng, Shih-chuw; Lu, Jian-wei; Wei, Ho-hsiang
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Molecules, 2012 Pirfenidone (5-methyl-1-phenyl-2(1H)-pyridone, PFD) is a small-molecule compound acting on multiple targets involved in pathological fibrogenesis and is effective to increase the survival of patients with fibrosis, such as idiopathic pulmonary fibrosis ...
Jun Chen +5 more
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Iridium‐Catalyzed Ionic Hydrogenation of Multi‐Aza Heterocycles
Angewandte Chemie, Volume 138, Issue 35, 24 August 2026.Saturated nitrogen‐containing heterocycles are ubiquitous in bioactive molecules and are thus attractive synthetic targets. A readily accessible cyclometalated iridium(III) complex reduces 14 different aromatic aza heterocycles to (partially)saturated multi aza‐heterocycles enlarging accessible chemical space while displaying high tolerance toward ...
Arthur Despois, Nicolai Cramer
wiley +1 more source
6-Bromo-1-[2-(2-oxo-1,3-oxazolidin-3-yl)ethyl]-1H-imidazo[4,5-b]pyridin-2(3H)-one
Acta Crystallographica Section E, 2010 The title compound, C11H11BrN4O3, features an ethane fragment substituted with an almost planar (r.m.s. deviation = 0.019 Å) imidazo[4,5-b]pyridone ring system and an envelope-shaped oxazolidine unit on separate C atoms.
H. Bel-Ghacham +4 more
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Synthesis of 2-Pyridone Derivatives Bearing an Electron-withdrawing Group on Nitrogen [PDF]
, 2007 1-Protected 2(1H)-pyridones are highly useful dienophiles because Diels-Alder reaction of 1-sulfonyl-2(1H)-pyridones gave the synthetic intermediate such as quinoline and isoquinoline derivatives.
渡邉, 一弘 +8 more
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Major Constituents of the Predominant Endophytic Fungi from the Nigerian Plants and
Natural Product Communications, 2008 In a chemical screening of fungal strains endophytic to Nigerian plants, Diaporthe phaseolorum , the endophyte of Bryophyllum pinnatum , gave cytochalasin D and (3 R ,4 R )-3,4,5-trihydroxy-1-tetralone, Neurospora discreta from Morinda lucida yielded ...
Abimbola A. Sowemimo +5 more
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Toxins, 2011 We have identified a novel nucleotide, 4-pyridone 3/5-carboxamide ribonucleoside triphosphate (4PyTP), which accumulates in human erythrocytes during renal failure.
Elizabeth A. Carrey +5 more
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Pyridonderivate aus 3-Amino-2H-azirinen und Cyclopropenonen
CHIMIA, 1978 Reaction of the 3-dimethylamino-2H-azirines 1a and 1b with diphenylcyclopropenone (2a) in ether or acetonitrile leads to the 2-dimethylamino-5,6-diphenyl-4(3H)-pyridones 3a and 3b in 70 and 80% yield, respectively. The structure of these 1:1-adducts has
Stanislav Chaloupka, Heinz Heimgartner
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4-Pyridone-3-carboxamide-1-β-D-ribonucleoside (4PYR)-A Novel Oncometabolite Modulating Cancer-Endothelial Interactions in Breast Cancer Metastasis. [PDF]
Int J Mol Sci, 2022 Koszalka P +7 more
europepmc +1 more source
Synthesis of 5-(substituted phenylazo)-6-hydroxy-4-methyl-3-cyano-2-pyridones from ethyl 3-oxo-2-(substituted phenylazo)butanoates, Short communication [PDF]
Journal of the Serbian Chemical Society, 2011 A new procedure for the synthesis of known azo pyridone dyes is presented. A series of 5-(substituted arylazo)-6-hydroxy-4-methyl-3-cyano-2-pyridones were prepared from ethyl 3-oxo-2-(substituted phenylazo)butanoates and cyanoacetamide in acetone using ...
GORDANA UŠĆUMLIĆ +3 more
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