Results 61 to 70 of about 9,299,574 (208)

Biosynthesis of (–)-Sambutoxin, a Fusarium 2-Pyridone Alkaloid Mycotoxin [PDF]

open access: yes, 2021
This dissertation describes the discovery by genome mining and the characterization of thebiosynthetic pathway for sambutoxin, a 4-hydroxy-2-pyridone alkaloid Fusarium mycotoxin.
Go, Louise
core  

Dichlorido[1-(1,10-phenanthrolin-2-yl)-2-pyridone]cadmium(II)

open access: yesActa Crystallographica Section E, 2008
In the title mononuclear complex, [CdCl2(C17H11N3O)], the CdII ion assumes a distorted trigonal–bipyramidal coordination geometry. The pyridone plane is twisted out of the 1,10-phenanthroline mean plane by 43.8 (3)°.
Jin-Min Li
doaj   +1 more source

Binuclear Copper‐Dependent Oxidative Enzymes Involved in Fungal Natural Product Modifications

open access: yesJournal of the Chinese Chemical Society, EarlyView.
This article summarizes recent biochemical characterizations of a new enzyme family named by the authors as binuclear copper‐dependent oxidative enzymes (BiNCOs). Found in fungal natural product biosynthesis, BiNCOs catalyze diverse CH functionalization reactions, including C(sp3)H halogenation, C(sp3)H hydroxylation, C(sp3)O macrocyclization, and ...
Chen‐Yu Chiang, Masao Ohashi, Yi Tang
wiley   +1 more source

Two New Megastigmane Sulphonoglucosides from

open access: yesNatural Product Communications, 2009
Phytochemical study of the methanol extract of Mallotus anisopodus led to the isolation of two new megastigmane sulphonoglucosides, namely anisoposides A (1) and B (2), along with junipetrioloside A (3), bergenin (4), α-tocopherol, and N 1 -methyl-2 ...
Chau Van Minh   +8 more
doaj   +1 more source

Comparative evaluation of noncanonical amino acids as site‐specific NMR probes for the complex of E. coli SSB with single‐stranded DNA without isotope labelling

open access: yesThe FEBS Journal, Volume 293, Issue 12, Page 3601-3620, June 2026.
Genetic encoding of noncanonical amino acids (ncAA) enables their site‐specific installation in proteins. This work compares the nuclear magnetic resonance (NMR) performance of different ncAAs in a large protein−DNA complex (~ 100 kDa) without isotope labelling. The ncAAs deliver readily detectable NMR signals in the complex between E.
Sreelakshmi Mekkattu Tharayil   +7 more
wiley   +1 more source

Ultrafast Decay Dynamics of the 21ππ* Electronic State of N‑Methyl-2-pyridone

open access: yes
The ultrafast decay dynamics of N-methyl-2-pyridone upon excitation in the near-ultraviolet range of 261.5–227.9 nm is investigated using the femtosecond time-resolved photoelectron spectroscopy method.
Wenping Wu (121781)   +5 more
core   +1 more source

Synthesis and Evaluation of Antitumor and Anti-Angiogenesis Activity of Pyrone- or Pyridone-Embedded Analogs of Cortistatin A

open access: yesMarine Drugs
Simplified analogs of cortistatin A were synthesized and biologically evaluated to develop novel antitumor substances that target angiogenesis. To analyze the effect of substituents at positions corresponding to C-2 and/or C-4 of the A-ring, various ...
Yuri Fujimoto   +4 more
doaj   +1 more source

New syntheses of 5,6- and 7,8-diaminoquinolines

open access: yesBeilstein Journal of Organic Chemistry, 2013
The synthesis of 5,6- and 7,8-diaminoquinoline derivatives starting from angularly annelated selenadiazoloquinolones is presented. Simple chlorination of the pyridone ring followed by reductive deselenation of the 1,2,5-selenadiazole ring afforded novel ...
Maroš Bella, Viktor Milata
doaj   +1 more source

Recent Approaches for the Synthesis of Pyridine and Quinoline Cores Present in Natural Products

open access: yesAdvanced Synthesis &Catalysis, Volume 368, Issue 10, 19 May 2026.
An anthology of the most recent methods used to synthesize pyridines and quinolines found in natural products over the last decade. Pyridines, quinolines, and their derivatives represent a class of significant heterocyclic compounds that are prevalent in a multitude of natural products, including alkaloids found in plants, fungi, insects, marine ...
Carl Bowman   +2 more
wiley   +1 more source

Surface‐Bound Superoxide Radical‐Mediated Photo‐Fenton Mineralization of Ciprofloxacin on Fe‐Sillenite Nanosheets

open access: yesAdvanced Science, Volume 13, Issue 29, 22 May 2026.
This study systematically compares the degradation efficiency of CIP in a H2O2‐alone system and a novel Bi12FeO20‐H2O2 photo‐Fenton system. It reveals for the first time the presence of a quinone‐imine intermediate in the H2O2‐alone system, which exhibits toxicity comparable to CIP.
Wenting Qiu   +9 more
wiley   +1 more source

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