Enzymatic synthesis of vitamin B6 precursor [PDF]
3-Cyano-4-ethoxymethyl-6-methyl-2-pyridone is an important precursor in the synthesis of vitamin B6, obtained in the addition reaction between 2-cyanoacetamide and 1-ethoxy-2,4-pentanedione catalyzed by lipase from Candida rugosa ...
Prlainović Nevena Ž. +4 more
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Low and deficient niacin status and pellagra are endemic in postwar Angola [PDF]
BACKGROUND: Outbreaks of pellagra were documented during the civil war in Angola, but no contemporary data on the incidence of pellagra or the prevalence of niacin deficiency were available.
Cheung, E +6 more
core +2 more sources
Crystal Chemistry of Zinc Quinaldinate Complexes with Pyridine-Based Ligands
Substitution of methanol in [Zn(quin)2(CH3OH)2] (quin− denotes an anionic form of quinoline-2-carboxylic acid, also known as quinaldinic acid) with pyridine (Py) or its substituted derivatives, 3,5-lutidine (3,5-Lut), nicotinamide (Nia), 3 ...
Barbara Modec
doaj +1 more source
Scientific Opinion on the safety and efficacy of niacin (nicotinic acid and nicotinamide) as a feed additive for all animal species based on a dossier submitted by Lonza Benelux BV [PDF]
<p>The term ‘niacin’ is used as a generic description of nicotinic acid and nicotinamide with pyridine as the basic structure. Nicotinic acid and nicotinamide function mainly as precursors of the co-enzymes NAD and NADP.
AWT (Arbeitsgemeinschaft für Wirkstoffe in der Tierernährung e.V.) +45 more
core +2 more sources
rac-2-Methyl-3,4,5,6-tetrahydro-2H-2,6-methano-1,3-benzoxazocin-4-one
The title compound, C12H13NO2, represents a conformationally restricted 2-pyridone analogue of 1,4-dihydropyridine-type calcium antagonists and was selected for a crystal structure determination in order to explore some aspects of drug-receptor ...
Viktor Kettmann +2 more
doaj +1 more source
Characterization studies of 1-(4-cyano-2-oxo-1,2-dihydro-1-pyridyl)-3-(4-cyano-1,2-dihydro-1-pyridyl)propane formed from the reaction of hydroxide Ion with 1,3-Bis-(4-cyano pyridinium)propane [PDF]
The aqueous alkaline reaction of 1,3-bis(4-cyanopyridinium)propane dibromide, a reactant constituted of two pyridinium rings linked by a three-methylene bridge, generates a novel compound,1 -(4-cyano-2-oxo-1,2-dihydro-1-pyridyl)-3-(4-cyano-1,2-dihydro-1 ...
CATALANI, Luiz H +7 more
core +1 more source
Photochemical Cycloadditions to 5,6-Dihydro-4-pyridones [PDF]
5,6-Dihydro-4-pyridones (3a-3c) undergo photochemical [2 + 2]-cycloaddition with olefins activated by an electron withdrawing group. Alkyl substituted double bonds could only be brought to react in the intramolecular cases 3d and 3e.
Guerry, Philippe, Neier, Reinhard
openaire +2 more sources
Synthesis of highly functionalized 2,2'-bipyridines by cyclocondensation of β-ketoenamides – scope and limitations [PDF]
The scope of a flexible route to unsymmetrically functionalized bipyridines is described. Starting from 1,3-diketones 1a–e, the corresponding β-ketoenamines 2a–e were converted into different β-ketoenamides 3a–g by N-acylation with 2-pyridinecarboxylic ...
Hommes, Paul, Reissig, Hans-Ulrich
core +2 more sources
Newborn Urinary Metabolic Signatures of Prematurity and Other Disorders: A Case Control Study [PDF]
This work assesses the urinary metabolite signature of prematurity in newborns by nuclear magnetic resonance (NMR) spectroscopy, while establishing the role of possible confounders and signature specificity, through comparison to other disorders.
Sílvia O. Diaz +13 more
core +3 more sources
Two new 4-hydroxy-2-pyridone alkaloids furanpydone A and B (1 and 2), along with two known compounds N-hydroxyapiosporamide (3) and apiosporamide (4) were isolated from the endophytic fungus Arthrinium sp.
Ying Yin +7 more
doaj +1 more source

