Results 31 to 40 of about 34,010 (190)
Supra and subgingival application of antiseptics or antibiotics during periodontal therapy
Periodontology 2000, EarlyView., 2023 Abstract Periodontal diseases (gingivitis and periodontitis) are characterized by inflammatory processes which arise as a result of disruption of the balance in the oral ecosystem. According to the current S3 level clinical practice guidelines, therapy of patients with periodontitis involves a stepwise approach that includes the control of the patient ...
Elena Figuero +5 more
wiley +1 more source
Communications Chemistry, 2023 The human pathogen Pseudomonas aeruginosa produces various 4(1H)-quinolones with diverse functions. Among these, 2-nonyl-4(1H)-quinolone (NQ) and its N-oxide (NQNO) belong to the main metabolites.
Viktoriia Savchenko +4 more
doaj +1 more source
Beilstein Journal of Organic Chemistry, 2019 Selectively methylated analogues of naturally occurring 2-heptyl-4(1H)-quinolones, which are alkaloids common within the Rutaceae family and moreover are associated with quorum sensing and virulence of the human pathogen Pseudomonas aeruginosa, have been
Sven Thierbach +3 more
doaj +1 more source
Quorum Sensing: suatu Sistem Komunikasi Bakteri Fitopatogen, Peranannya pada Proses Infeksi, dan Peluangnya sebagai Basis Pengembangan Strategi Baru dalam Pengendalian Penyakit Tumbuhan [PDF]
, 2009 Previously, it is thought that bacterium is an autonomous unicellular organism with no capacity for collective behavior. Now the paradigm has changed since there are communication between intercell bacteria.
Hadiwiyono, H. (Hadiwiyono)
core +2 more sources
Nonclassical Biological Activities of Quinolone Derivatives
Journal of Pharmacy & Pharmaceutical Sciences, 2011 Quinolones are considered as a big family of multi-faceted drugs; their chemical synthesis is flexible and can be easily adapted to prepare new congeners with rationally devised structures.
Mohsen Daneshtalab, Abeer Ahmed
doaj +1 more source
Communications Chemistry, 2022 Quinolones can possess desirable antibacterial, antiviral and anticancer properties, rending them important synthetic targets for drug discovery purposes.
Feng-Wei Guo +7 more
doaj +1 more source
Docking studies on novel analogs of quinolones against DNA gyrase of Escherichia coli [PDF]
Journal of Pharmacy & Pharmacognosy Research, 2018 Context: Bacterial resistance to antibiotics is the inevitable consequence of the use of antimicrobial agents. Thus, quinolones are an important class of antibacterials; these agents generally consist of a 1-subtituted-1,4-dihydro-4-oxopyridine-3 ...
Cristian Davila +3 more
doaj
Microwave assisted synthesis of 4-quinolones and N,N′-diarylureas
Green Processing and Synthesis, 2013 4-Quinolinones are an important class of alkaloids, widely used as conventional drugs to treat various infectious diseases. In this study, we report the synthesis of 4-quinolones in one step, under microwave irradiation and with diphenyl ether as a ...
Duarte Patricia D. +2 more
doaj +1 more source
Rapid assessment of the effect of ciprofloxacin on chromosomal DNA from using an in situ DNA fragmentation assay [PDF]
, 2009 Background Fluoroquinolones are extensively used antibiotics that induce DNA double-strand breaks (DSBs) by trapping DNA gyrase and topoisomerase IV on DNA.
Gosalvez Jaime +4 more
core +1 more source
1,2-Substituted 4-(1H)-Quinolones: Synthesis, Antimalarial and Antitrypanosomal Activities in Vitro
Molecules, 2014 A diverse array of 4-(1H)-quinolone derivatives bearing substituents at positions 1 and 2 were synthesized and evaluated for antiprotozoal activities against Plasmodium falciparum and Trypanosoma brucei rhodesiense, and cytotoxicity against L-6 cells in ...
Abraham Wube +6 more
doaj +1 more source