Results 41 to 50 of about 34,010 (190)

In-vitro activity of newer quinolones against aerobic bacteria [PDF]

open access: yes, 2017
Nalidixic and five newer 4-quinolones, ciprofloxacin, enoxacin, norfloxacin, ofloxacin and pefloxacin were tested against 576 recent clinical aerobic bacterial isolates.
Auckenthaler, R.   +2 more
core  

Quinolone-resistant Escherichia coli [PDF]

open access: yes, 2008
Quinolones (nalidixic acid - NAL, norfloxacin - NOR, ciprofloxacin - CIP and gatifloxacin - GAT) were tested against Escherichia coli isolated from urine (385 patient samples) by disk diffusion (DD) and agar dilution (AD) methods. Fifty-three samples (13.
Dalla Costa, Libera Maria   +4 more
core   +2 more sources

Surface‐Bound Superoxide Radical‐Mediated Photo‐Fenton Mineralization of Ciprofloxacin on Fe‐Sillenite Nanosheets

open access: yesAdvanced Science, EarlyView.
This study systematically compares the degradation efficiency of CIP in a H2O2‐alone system and a novel Bi12FeO20‐H2O2 photo‐Fenton system. It reveals for the first time the presence of a quinone‐imine intermediate in the H2O2‐alone system, which exhibits toxicity comparable to CIP.
Wenting Qiu   +9 more
wiley   +1 more source

SYNTHESIS OF VARIOUS BIOPRECURSORS OF QUINOLONE DERIVATIVES AS ANTI-INFECTIVE AGENTS

open access: yesZagazig Journal of Pharmaceutical Sciences, 2005
A series of 1-ethyl-7-methyl, 4-dihydro-4-oxo-N-substituted-1,8-naphthyndine-3-carboxamido derivatives (1-8) as prodrugs and 6-substituted quinolones were prepared. Rapresentatives of the new compounds were subjected to microbiological screening.
Mansour Hasanein   +3 more
doaj   +1 more source

Mining Public Mass Spectrometry Data to Characterize the Diversity and Ubiquity of P. aeruginosa Specialized Metabolites

open access: yesMetabolites, 2020
Pseudomonas aeruginosa is a ubiquitous environmental bacterium that causes chronic infections of burn wounds and in the lungs of cystic fibrosis (CF) patients.
Andrew C. Lybbert   +4 more
doaj   +1 more source

Occurrence of multi-antibiotics in chicken and egg samples in Hubei

open access: yesZhongguo shipin weisheng zazhi, 2022
ObjectiveTo investigate the residues of quinolones,tetracyclines and metronidazole in chicken and egg samples in Hubei from 2016 to 2019.MethodsA total of 373 chicken and 365 egg samples collected from 15 cities in Hubei Province were detected by ultra ...
XIAO Yonghua   +4 more
doaj   +1 more source

Mechanisms of Mitochondrial Toxicity and Cytotoxicity Caused by Pseudomonas aeruginosa Pyocyanin in Human Nasal Epithelial Cells

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Pseudomonas aeruginosa is an opportunistic pathogen in cystic fibrosis‐related chronic rhinosinusitis (CF‐CRS) that produces phenazine metabolites pyocyanin and 1‐hydroxyphenazine (1‐HP), which may have detrimental effects on mitochondria, reactive oxygen species (ROS), Ca2+ signaling, and apoptosis.
Joel C. Thompson   +8 more
wiley   +1 more source

Integrating One Health to Mitigate the Emergence and Spread of Antimicrobial Resistance in Livestock and Aquaculture

open access: yesAnimal Research and One Health, EarlyView.
Antimicrobial resistance (AMR) is an escalating global threat driven by antimicrobial use in aquaculture and livestock. Resistant pathogens and genes can spread across humans, animals, and the environment through interconnected ecosystems. Using a One Health approach, this review emphasizes antimicrobial stewardship, regulatory strengthening, enhanced ...
Mir Mohammad Ali   +10 more
wiley   +1 more source

Identification of Anziaic Acid, a Lichen Depside from Hypotrachyna sp., as a New Topoisomerase Poison Inhibitor [PDF]

open access: yes, 2013
Topoisomerase inhibitors are effective for antibacterial and anticancer therapy because they can lead to the accumulation of the intermediate DNA cleavage complex formed by the topoisomerase enzymes, which trigger cell death.
Annamalai, Thirunavukkarasu   +6 more
core   +8 more sources

Previous use of quinolones: A surrogate marker for first line anti-tuberculosis drugs resistance in HIV-infected patients?

open access: yesBrazilian Journal of Infectious Diseases, 2012
Objectives: Drug resistant Mycobacterium tuberculosis causes much higher rates of treatment toxicity, failure or relapse, and mortality. We determined the drug resistant profile of Mycobacterium tuberculosis strains isolated from a population of HIV ...
Caroline Deutschendorf   +2 more
doaj   +1 more source

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