Results 1 to 10 of about 11,648,543 (253)
Synthesis and Evaluation of Antimicrobial Activity of 1, 3, 4-Thiadiazole Analogues for Potential Scaffold. [PDF]
J Pharmacopuncture, 2021 Pathogenic microbes are causal agents for various types of severe and even lethal infectious diseases. Despite of development in medication, bacterial and fungal infections still persist to be a vital problem in health care. Bacteria and several fungal species have shown resistance to antibiotics used in treatment to current medications.
Sahu S, Sahu T, Kalyani G, Gidwani B.
europepmc +6 more sources
Journal of Chemistry, 2022 A series of novel thiochroman-4-one derivatives incorporating carboxamide and 1, 3, 4-thiadiazole thioether moieties were synthesized. Bioassay results indicated that the EC50 values of compound 6-chloro-N-(5-(methylthio)-1, 3, 4-thiadiazol-2-yl)-4 ...
Lu Yu +5 more
doaj +2 more sources
Synthesis and cytotoxic activity evaluation of some new 1, 3, 4-oxadiazole, 1, 3, 4-thiadiazole and 1, 2, 4- triazole derivatives attached to phthalimide. [PDF]
Res Pharm Sci, 2021 Background and purpose: In the last few decades, nitrogen-rich heterocyclic compounds such as 1, 3, 4-thiadiazoles, 1, 2, 4-triazoles and 1, 3, 4-oxadiazoles have received considerable attention because of their notable biological properties, especially ...
Hassanzadeh F +3 more
europepmc +2 more sources
Synthesized azodyes of 2-amino-1, 3, 4- thiadiazole - 5 - thiol
مجلة بغداد للعلوم, 2011 Several azo dyes were synthesized through coupling reaetion of some substituted phenols and B.naphthol with diazonium salt of 2- amino-1,3-4- thiadiazol -5- thiol. All the synthesized compounds during this work were characterized using some speetral data
Baghdad Science Journal
doaj +4 more sources
A COMPUTATIONAL STUDY OF SUBSTITUENT EFFECT 1, 3, 4-THIADIAZOLE ON CORROSION INHIBITION
Azerbaijan Chemical Journal, 2023 A theoretical study of 1, 3, 4-thiadiazole with nine various derivatives in gaseous and aqueous phases was investigated by employing the density functional theory (DFT) at 6-311++(d, p) basis set and Becke’s three parameters hybrid exchange-correlation functional (B3LYP).
Mohammad Qadr Hiwa, Mustafa Mamand Dyari
openaire +2 more sources
Antimicrobial activity of 1, 3, 4-thiadiazole derivatives: a recent review [PDF]
Journal of Applied Pharmaceutical Research, 2018 A few five members’ aromatic systems having three hetero-atoms at symmetrical positions, for example, thiadiazoles have been considered broadly attributable to their intriguing pharmacological properties. These thiadiazole derivatives are the heterocyclic compound which contains the five member ring along with nitrogen and sulfur atoms.
Alam, Faruk
openaire +6 more sources
Synthesis, Characterization and Biological Activates Studies of some New Derivatives From 2-aminoo-5-mercapto-1, 3, 4-thiadiazole [PDF]
مجلة بغداد للعلوم, 2018 In this work, thiadiazole derivatives were prepared by taking advantage of active sites in (2-amino-5-mercapto-1, 3, 4-thiadiazole) as a starting material base.
Baghdad Science Journal
doaj +3 more sources
Theoretical Study of Interaction Between Thiadiazole Derivatives on Fe(110) Surface [PDF]
Journal of Chemistry Letters, 2023 The theoretical performance of 4-methoxyphenyl-1,3,4-thiadiazole (AMPT), 2-Amino-5-(4-chlorophenyl)-1,3,4-thiadiazole (ACPT) and 2-amino-5-phenyl-1,3,4-thiadiazole (APT) as inhibitors of iron corrosion was assessed with a view of determining the ...
Thomas Nyijime +3 more
doaj +1 more source
International Journal of Pharmaceutical Quality Assurance, 2023 The development of novel antitumor agents is paramount in the fight against drug resistance and its associated cardiotoxicity. The present study carried out a thorough anticancer evaluation of N- (4-oxo-2-(4-((5-aryl-1,3,4 thiadiazole-2yl) amino) phenyl ...
Amit Chawla +4 more
semanticscholar +1 more source
Molecules, 2022 Pyridine, 1,3,4-thiadiazole, and 1,3-thiazole derivatives have various biological activities, such as antimicrobial, analgesic, anticonvulsant, and antitubercular, as well as other anticipated biological properties, including anticancer activity.
A. Abouzied +7 more
semanticscholar +1 more source