Results 91 to 100 of about 12,853,486 (222)

Phototherapy Strategies for Cancer Treatment: Mechanisms and Emerging Nanomaterials

Aggregate, Volume 7, Issue 10, October 2026.
Phototherapy offers spatiotemporally controlled cancer treatment by converting light into heat, reactive oxygen species, immune activation, and therapeutic gas release. This review summarizes the mechanisms and emerging nanomaterials for photothermal therapy, photodynamic therapy, photoimmunotherapy, and photo‐gas therapy, emphasizing structure ...
Fan Liu, Jun Huang
wiley   +1 more source

Antifungal Activity of Novel Indole Derivatives Containing 1,3,4-Thiadiazole

In this study, 24 indole derivatives containing 1,3,4-thiadiazole were discovered and synthesized. The target compounds’ antifungal efficacy against 14 plant pathogenic fungal pathogens was then determined in vitro.
Bangcan He (18452570), Yishan Qing (18452573), Kaini Meng (18320251), Wei Xue (219900), Zhenchao Wang (162315), Zhiling Sun (4454473), Yuzhi Hu (3274479), Wei Zeng (126658), Li Xing (35790)   +8 more
core   +1 more source

Diethyl {(4-methoxyphenyl)[5-(4-nitrophenyl)-1,3,4-thiadiazol-2-ylamino]methyl}phosphonate

Acta Crystallographica Section E, 2008
The title compound, C20H23N4O6PS, was synthesized by the reaction of N-(4-methoxybenzylidene)-5-(4-nitrophenyl)-1,3,4-thiadiazol-2-amine and diethyl phosphite. The thiadiazole and nitro-substituted phenyl rings in the molecule are approximately coplanar,
Li-He Yin, Rong Wan, Feng Han, Bin Wang, Jin-Tang Wang   +4 more
doaj   +1 more source

Synthesis and cytotoxic activity evaluation of some new 1, 3, 4-oxadiazole, 1, 3, 4-thiadiazole and 1, 2, 4- triazole derivatives attached to phthalimide. [PDF]

Res Pharm Sci, 2021
Hassanzadeh F, Jafari E, Shojaei F, Sadeghi-Aliabadi H.   +3 more
europepmc   +1 more source

Development of Benzothiophene–Bearing Bis–oxadiazole Derivatives for Potential Anticancer Targets: Evaluation of DFT, ADME–Tox, and In Silico Docking

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Innovative synthesis of a novel benzothiophene–based bis–oxadiazole derivatives. The structural characterization was performed using experimental and theoretical methods. Significant anticancer activity against selected cancer cell lines. Three derivatives showed good activity 7b, 7g and 7i with IC50 values 7.5 ± 1.04 and 9.5 ± 1.01 µg/mL.
Nagaraju Madala, Vishal Sharma, Srilalitha Vinnakota   +2 more
wiley   +1 more source

Synthesis of Related Compounds of Thiosemi-carbazide. IV. 1-(1, 3, 4-Thiadiazol-2-yl)-2-pyrazolin-5-one and Tetrazolo [4, 5-a]-1, 3, 4-thiadiazole Derivatives.

Chemical and Pharmaceutical Bulletin, 1958
1) 1-(5-R-1, 3, 4-Thiadiazol-2-yl)-3-methyl-4-R'-2-pyrazolin-5-one (R'=H, iso-C3H7) (III) were synthesized starting with 2-hydrazino-5-R-1, 3, 4-thiadiazole (I : R=CH3, C2H5, n-C3H7, iso-C4H9, C6H5), and reacting them with ethyl acetoacetate or ethyl 3-acetyliso-valerate to form 5-R-1, 3, 4-thiadiazolylhydrazone (II).
openaire   +3 more sources

PolarEyes with enhanced digital imaging, a high‐throughput solution for locating and grading crystals

Journal of Applied Crystallography, Volume 59, Issue 5, Page 1557-1569, October 2026.
An open‐source program for the calculation and visualization of polarization‐derived properties of crystalline material is described, alongside the integration of a polarizing image sensor into a home‐built high‐throughput imaging setup.The long‐range internal order of crystals enables them to exhibit a well known and long‐exploited phenomenon ...
Thomas D. Smith, Alexandra Longcake, Michael J. Hall, Michael R. Probert   +3 more
wiley   +1 more source

N-[4-Acetyl-5-(2-methylprop-1-enyl)-5-(2-p-tolylpropyl)-4,5-dihydro-1,3,4-thiadiazol-2-yl]acetamide

Acta Crystallographica Section E, 2009
The title heterocyclic compound, C20H27N3O2S, was synthesized from 2-(4-methylcyclohex-3-enyl)-6-methylhepta-2,5-dien-4-one, which was isolated from the essential oil Cedrus atlantica.
Noureddine Mazoir, Lahcen El Ammari, Nouzha Bouhmaida, Slimane Dahaoui, Ahmed Benharref, Moha Berraho   +5 more
doaj   +1 more source

Complex multitrophic species interactions and fitness costs: Intricate consequences of jasmonate and salicylate induced plant defences

Journal of Animal Ecology, Volume 95, Issue 10, Page 1859-1875, October 2026.
This study reveals how long‐term activation of jasmonic and salicylic acid signalling reshapes arthropod communities and plant fitness across seasons. By showing that induced defences generate contrasting outcomes and cascading trade‐offs across trophic levels, it challenges the assumption that induced resistance is uniformly beneficial in natural ...
Mônica F. Kersch‐Becker, Guilherme P. Pinheiro, Thaís S. Schweller, Martin Pareja, Victoria M. Pocius, José R. Trigo, Gustavo Q. Romero   +6 more
wiley   +1 more source

Synthesis of 5-Methyl-4-phthalimido-1,2,3-thiadiazole and 4-Phthalimidomethyl-1,2,3-thiadiazole

, 2014
Biologically, 1,2,3-thiadizoles have inhibitory effects on necroptosis, a mechanism that regulates cell death. The mechanism is involved in illnesses including stroke, myocardial infarction, and trauma. Molecules that can inhibit necroptosis could reveal
Barton, James, Benham, Vanessa
core   +1 more source