Solvent Induced Disulfide Bond Formation in 2,5-dimercapto-1,3,4-thiadiazole [PDF]
Disulfide bond formation is the decisive event in the protein folding to determine the conformation and stability of protein. To achieve this disulfide bond formation in vitro, we took 2,5-dimercapto-1,3,4-thiadiazole (DMcT) as a model compound. We found
Palraj Kalimuthu +2 more
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5-(2-Fluoro-4-nitrophenyl)-1,3,4-thiadiazole-2-amine [PDF]
The title compound, C8H5FN4O2S, was synthesized by the reaction of 2-fluoro-4-nitrobenzoic acid and thiosemicarbazide. The dihedral angle between the thiadiazole and benzene rings is 27.1 (2)°.
Peng Wang, Yao Wang, Feng Han, Rong Wan
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Synthesis of 5-Methyl-4-phthalimido-1,2,3-thiadiazole and 4-Phthalimidomethyl-1,2,3-thiadiazole [PDF]
Biologically, 1,2,3-thiadizoles have inhibitory effects on necroptosis, a mechanism that regulates cell death. The mechanism is involved in illnesses including stroke, myocardial infarction, and trauma. Molecules that can inhibit necroptosis could reveal
Barton, James, Benham, Vanessa
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MOESM1 of The effect of carbamic acid, (1,2,3-thiadiazole-4-ylcarbonyl)-hexyl ester on Peronophythora litchii infection, quality and physiology of postharvest litchi fruits [PDF]
Additional file 1: Figure S1. Identification of 4 phenolic compounds in HPLC chromatogram, a=procyanidin B1; b=catechin; c=(−)- epicatechin and d=(−)- epicatechin −3-gallate, there retention time were 16.3, 18.4, 20.9 and 22.3 min, respectively.
Fuying Luo (3766519) +4 more
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THE SYNTHESIS OF NEW 1,2,3-THIADIAZOLE DERIVATIVES [PDF]
The reactions of 1,2,3-thiadiazole-4-carbonyl chloride with the appropriate amines led to formation of the following amides in good yield: N-ethyl-1,2,3-thiadia- zole-4-carboxamide; N-methyl-1,2,3-thiadiazole-4-carbox- amide; N-cyclohexyl-1,2,3 ...
PATTERSON, RONALD BRINTON
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International audienceAbstract An original and efficient palladium‐catalyzed amination of imidazo[2,1‐ b ][1,3,4]thiadiazole is reported. The S N Ar and Buchwald–Hartwig cross‐coupling reactions were investigated to access C‐2 aminated imidazo[1,2‐ b ][1,
Buron, Frédéric +11 more
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Synthesis, characterization and biological activities of substituted oxadiazole, triazole, thiadiazole and 4-thiazolidinone derivatives [PDF]
2189-2194The synthesis and biological activities (anti-inflammatory and antibacterial) of a number of 2,5-substituted 1,2,4-triazole, 1,3 ,4-thiadiazole/oxadiazole and 2,3-substituted-4-thiazolidinone derivatives are described.
Amir, Mohd +5 more
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Coordination polymers formed by diorganotin dichlorides with 2,5-bis(4-pyridyl)-1,3,4-thiadiazole [PDF]
Dichlorodimethyltin and dichlorodiphenyltin form 1:1 adducts with 2,5-bis(4-pyridyl)-1,3,4-thiadiazole (L1). MOssbauer spectra of the compounds SnCl2(CH3)(2) . L1 (1) and SnCl2(C6H5)(2) . L1 .
MARTON, DANIELE +3 more
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Síntese de novos mesógenos derivados do heterocíclo imidazo[2,1-b][1,3,4]tiadiazol [PDF]
TCC (graduação) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas, Curso de Química.A síntese de seis novas moléculas derivadas do heterociclo imidazo[2,1-b][1,3,4]tiadiazol foram realizadas a partir da construções de ...
Ferraz Neto, José
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2-Amino-1,3,4-thiadiazole as a potential scaffold for promising antimicrobial agents [PDF]
Georgeta Serban,1,* Oana Stanasel,2,* Eugenia Serban,3 Sanda Bota2,* 1Pharmaceutical Chemistry Department, Faculty of Medicine and Pharmacy, University of Oradea, Oradea, Romania; 2Chemistry Department, Faculty of Sciences, University of Oradea, Oradea,
Serban G, Serban E, Stanasel O, Bota S
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