Synthesis and Docking Study on Thiadiazolo[3,2-a][1,3]diazepin-8(5H)-one Derivatives as Selective GABAA agonists [PDF]
HIE-124 is the new member of ultra-short acting hypnotics drug family. In this research, thiadiazole can act as the bio-isosteric replacement of thiazole in synthesized compounds as HIE-124 derivatives.
M. J. Taghizadeh, A. Javidan, A. Salmani
doaj
2-amino-5-mercapto-1,3,4-thiadiazole [I] were prepared by the cyclization of thiosemecarbazide with carbon disulphide and anhydrous sodium carbonate in ethanol as a solvent.
Ali H. Samir +2 more
doaj
Tuning the conjugated bridges between the electron-donor and electron-acceptor moieties plays a crucial role in enhancing the memristive properties of organic materials, yet it is rarely reported.
Xianglin Wang +7 more
doaj +1 more source
Synthesis, Corrosion Inhibition and Theoretical Studies of (E)-2-((2,5-Dichlorophenyl)diazenyl)naphthalen-1-ol as Corrosion Inhibitor of Mild Steel in 0.5 M Hydrochloric Acid [PDF]
The inhibitory capacity of (E)-2-((2,5-dichlorophenyl)diazenyl)naphthalen-1-ol (DPD) against mild steel corrosion in 0.5 M HCl has been studied at different temperature (25 – 65 ºC) by gravimetric and electrochemical methods. Quantum chemical study using
Aboluwoye, Christopher +4 more
core +1 more source
Advanced spectroscopic and theoretical study and assessment of antimycotic potential in a synergistic composition of a 1,3,4-thiadiazole derivative and amphotericin B [PDF]
The paper presents the results of an in-depth spectroscopic, theoretical (quantum chemical), and microbiological study conducted on a promising, synergistic composition of a newly considered 1,3,4-thiadiazole derivative, 1,3,4-thiadiazole: 2,4-dihydroxy ...
Gagoś, Mariusz +7 more
core +2 more sources
1, 3, 4-Thiadiazoles: An Overview [PDF]
openaire +1 more source
Synthesis and Invitro Anti-Cancer Evaluation of Disubstituied 1,2,4 Thiadmzole Derivatives [PDF]
INTRODUCTION: Chemistry is a very broad subject, and can justly claim to encompass many aspects of the study of biological molecules. To most researchers in the cancer fields, the term ‘chemistry’ is often used in a much narrower way and is synonymous ...
Shalini, S
core
Studies on 1, 3, 4-Thiadiazole Derivatives. X
Masaki Ohta, Hiroshi Kimoto
openaire +2 more sources
Characterization & Invitro Antioxidant Activity of 1, 3, 4 Thiadiazole Derivatives of Thiazolidinone
In view of the considerable importance of thiadiazoles and thiazolidinones, which are the core structures in a variety of pharmaceuticals with a broad spectrum of biological activity. Synthesis of series of potential biological active 1, 3, 4 thiadiazole linked 4 thiazolidinone derivatives were obtained via a multistep synthesis sequence with a simple ...
Vandana K +4 more
openaire +1 more source
Studies on 1, 3, 4-Thiadiazole Derivatives. VIII
Masaki Ohta, Hiroshi Oya, Akira Mifune
openaire +2 more sources

