Results 181 to 190 of about 12,853,486 (222)

Amplified aggregation-induced emission via donor-acceptor-donor molecular architecture: a high-sensitivity lateral flow immunoassay platform. [PDF]

J Nanobiotechnology
Bai X, Zhang H, Zhang R, Liu Z, Pang W, Mao Z, Liu Z, Zhou H, Gao Z.   +8 more
europepmc   +1 more source

Structure-Guided Optimization and Biological Validation of 1,3,4-Thiadiazole-Based SIRT2 Inhibitors Reinforcing Channel Entrance Interactions. [PDF]

Drug Dev Res
Aksel AB, Ozgencil F, Bakar-Ates F, Gunindi HB, Massarotti A, Ozkan E, Kaya SG, Gozelle M, Ozkan Y, Eren G.   +9 more
europepmc   +1 more source

Diverse Biological Activities of 1,3,4-Thiadiazole Scaffold

Chemistry, 2022
The chemistry of 1,3,4-thiadiazole is one of the most interesting scaffolds for synthesizing new drug molecules due to their numerous pharmacological activities.
Sumitra Nain, Sarvesh Paliwal
exaly   +2 more sources

Synthesis and antifungal activity of thiadiazole-functionalized chitosan derivatives

Carbohydrate Research, 2013
A groups of novel water soluble chitosan derivatives containing 1,3,4-thiadiazole group were synthesized including 1,3,4-thiadiazole (TPCTS), 2-methyl-1,3,4-thiadiazole (MTPCTS), and 2-phenyl-1,3,4-thiadiazole (PTPCTS).
Qing Li, Zhanyong Guo, Guodong Gu
exaly   +2 more sources

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4-Thiadiazole: The Biological Activities

Systematic Reviews in Pharmacy, 2018
4-Thiadiazole (1,3,4-thiadiazole) nucleus displayed noteworthy industrial efficiencies and has shown various biological activities, especially as a cancer chemo preventive agent. 4-Thiadiazole has been categorized as a member of family of azole that consist of thiadiazole ring.
Hiba Ibraheem, Yasmeen Al-Majedy, Ahmed Al-Amiery   +2 more
openaire   +1 more source

Antimicrobial Activity of 1, 3, 4-Thiadiazole & Its Derivative

2022
For a long time, researchers have been fascinated by the chemistry of heterocyclic compounds. The 1,3,4-thiadiazole heterocyclic nucleus is a crucial family of compounds for the development of new medications. The synthesis of novel thiadiazole derivatives, as well as the investigation of their chemical and biological activity, has grown increasingly ...
Lade, Pranali P., A.Thorat, Akshay, Jadhav, Sayali S., Devkar, Aniket T., Mohite, Shrinivas K.   +4 more
openaire   +1 more source

SYNTHESIS AND METHYLATION OF SOME 1,2,4-THIADIAZOLE-5-THIONES

Phosphorus, Sulfur and Silicon and the Related Elements, 1992
3,4-Disubstituted-1,2,4-thiadiazole-5(4H)-thiones (4) have been prepared by the treatment of 3,4-di-substituted-1,2,4-thiadiazole-5(4H)-ones (3) with P4S10.
Yaşar Dürüst, Hikmet Agirbas
exaly   +2 more sources

Some biochemical effects of 2-ethylamino-1, 3, 4-thiadiazole

Biochemical Pharmacology, 1959
Abstract It has previously been demonstrated (Kaplan et a 4 ), that the injection of large doses of nicotinamide results in a ten-fold increase in the diphosphopyridine nucleotide (DPN) content of the liver of mice. The current report shows that the nicotinamide antagonist 2-ethylamino-1,3,4-thiadiazole (EAT) does not behave as a competitive ...
Louis Shuster, Abraham Goldin
openaire   +1 more source

Microwave Assisted Synthesis and Antibacterial Evaluation of 1, 3, 4-Thiadiazole Derivatives

Research Journal of Pharmacy and Technology, 2021
1,3,4-Thiadiazole is an important heterocyclic moiety, forms an integral core structural component of different categories of drugs such as antimicrobial, antitubercular, anti-inflammatory, antiepileptic, antiviral, antineoplastics, and analgesic agents. It is a key moiety in current discovery and designing of new drugs.
Jayalakshmi P M, Sheeba Jasmin TS, Manu Jose   +2 more
openaire   +1 more source