Results 191 to 200 of about 12,853,486 (222)
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A None-Spot Synthesis of 1, 3, 4-Thiadiazole Derivative by Conventional and Modern Technique
2021An efficient and one-pot synthesis is described for the 1, 3,4-thiadiazole derivatives by a conventional and modern technologies such as microwave irradiation. The reaction of chloro and fluoro substituted aromatic carboxylic acid with thiosemicarbazide carried in the presence of phosphorus oxychloride heating at 110 0C and .
Dhotre, Bharat +4 more
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[Synthesis and antimycotic activity of derivatives of 1, 3, 4-thiadiazole (3,2a) pyrimidone].
Il Farmaco; edizione scientifica, 1981As a continuation of previous research designed to obtain derivatives of 1,3,4-thiadiazole of pharmacological interest, some derivatives of 1,3,4-thiadiazole[3,2-alpha]pyrimidin-5-one and isomeric 7-one were prepared. The fungistatic activity of the products was tested in vitro against the following: Candida albicans, Candida parapsilosis, Candida ...
Russo F +3 more
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Research Journal of Pharmacy and Technology, 2018
In this work, thiadiazole derivatives were prepared by taking advantage of active sites in (2-amino-5-mercapto-1,3,4-thiadiazole) as base. The main hetrocyclic compounds (1,3,4-thiadiazole, oxazole) etc. 2-amino-5-mercapto-1,3,4-thiadiazole compound [1] was prepared by cyclic closure of thiosemicarbazide compound with anhydrous sodium carbonate and ...
Shetha. F. Al-Zubiady +2 more
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In this work, thiadiazole derivatives were prepared by taking advantage of active sites in (2-amino-5-mercapto-1,3,4-thiadiazole) as base. The main hetrocyclic compounds (1,3,4-thiadiazole, oxazole) etc. 2-amino-5-mercapto-1,3,4-thiadiazole compound [1] was prepared by cyclic closure of thiosemicarbazide compound with anhydrous sodium carbonate and ...
Shetha. F. Al-Zubiady +2 more
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Synthesis and biological evaluation of 5-fatty-acylamido-1, 3, 4-thiadiazole-2-thioglycosides
Bioorganic & Medicinal Chemistry Letters, 2017In the present study, the synthesis of 1, 3, 4-thiadiazole-based thioglycosides were accomplished in good yields with employing a convergent synthetic route. The starting material 5-amino-1, 3, 4-thiadiazole-2-thiol and followed by a series of 5-fatty-acylamido-1, 3, 4-thiadiazole-2-thiols (4a-4j) were synthesized with different fatty acid chlorides ...
Srikanth, Vudhgiri +5 more
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3D QSAR Studies on 1, 3, 4-Thiadiazole Derivatives: An Approach to Design Novel Anticonvulsants
Medicinal Chemistry, 2010A three-dimensional quantitative structure-activity relationship (3D-QSAR) study was performed on a series of 1, 3, 4-thiadiazole derivatives reported as anticonvulsant employing self-organizing molecular field analysis (SOMFA) techniques to investigate the structural requirements for the design of novel anticonvulsant.
Suresh, Thareja +4 more
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Synthesis, characterization and biological activity of some 1, 3, 4-thiadiazol derivatives.
Pakistan journal of pharmaceutical sciences, 2012Thiadiazoles are their derivatives exhibit a wide variety of pharmacological activities such as Antibacterial and anti-inflammatory. In the present study we have synthesized derivatives some 2,5 substituted 1,3,4- thiadiazoles. The structures of these synthesized compounds were confirmed by IR, NMR, and MASS spectra data. These compounds were evaluated
Arvind Kumar, Singh +2 more
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Australian Journal of Chemistry, 1985
A series of mono- and bis -(5'-substituted 1',3',4'-thiadiazol-2'- yl )pyridines with strongly basic side chains, e.g., 3,5-bis[5'(2'-N,N- dimethylaminoethylthio )-1',3',4'-thiadiazol-2'-yl]pyridine (1), and (5?-substituted 1',3',4'-thiadiazol-2'-ylmethyl)pyridines have been prepared for evaluation as amplifiers of phleomycin.
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A series of mono- and bis -(5'-substituted 1',3',4'-thiadiazol-2'- yl )pyridines with strongly basic side chains, e.g., 3,5-bis[5'(2'-N,N- dimethylaminoethylthio )-1',3',4'-thiadiazol-2'-yl]pyridine (1), and (5?-substituted 1',3',4'-thiadiazol-2'-ylmethyl)pyridines have been prepared for evaluation as amplifiers of phleomycin.
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302. Preparation and hydrolysis of some derivatives of 1 : 3 : 4-thiadiazole
Journal of the Chemical Society (Resumed), 1958V. Petrow +3 more
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A Review on Antidiabetic Activity of Substituted 1, 3, 4-Thiadiazole Derivatives.
Research Journal of Pharmacy and Technology, 2017Yogesh Vaishnav +4 more
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