Results 11 to 20 of about 5,910 (205)
Structure-Guided Optimization and Biological Validation of 1,3,4-Thiadiazole-Based SIRT2 Inhibitors Reinforcing Channel Entrance Interactions. [PDF]
Drug Dev ResABSTRACT SIRT2, the cytoplasmic member of the sirtuin family, is generally acknowledged to promote cancer and contribute to the progression of various pathologies, including neurodegeneration, inflammation, obesity, and bacterial infection through the deacetylation of target substrates.
Aksel AB +9 more
europepmc +2 more sources
Synthesis and Characterization of Five, Sevene Heterocyclic Membered Rings
مجلة بغداد للعلوم, 2013 New compounds containing heterocyclic units have been synthesized. These compounds include 2-amino 5- phenyl-1,3,4-thiadiazole (1) as starting material to prepare the Schiff bases 2N[3-nitrobenzylidene -2 hydroxy benzylidene and 4-N,N-dimethyl ...
Baghdad Science Journal
doaj +1 more source
مجلة بغداد للعلوم, 2015 2- amino -5- thiol-1,3,4- thiadiazole (S1) was prepared by cyclic locking of thiosemicarbazide in the presence of anhydrous sodium carbonate and CS2. diazotization of (S1) compound gave diazonium salt (S2) that reacts with different activated aromatic ...
Baghdad Science Journal
doaj +1 more source
Molecules, 2011 A new series of thiadiazole-enaminones 4 were synthesized via reactions of 5-acetyl-1,3,4-thiadiazoles 3 with dimethylformamide-dimethylacetal (DMF-DMA).
Thoraya A. Farghaly +2 more
doaj +1 more source
Acta Crystallographica Section E: Crystallographic Communications, 2020 Three title compounds, namely, 2-(4-chlorobenzyl)-5-[(1H-indol-3-yl)methyl]-6-phenylimidazo[2,1-b][1,3,4]thiadiazole, C26H19ClN4S, (I), 2-(4-chlorobenzyl)-6-(4-fluorophenyl)-5-[(1H-indol-3-yl)methyl]imidazo[2,1-b][1,3,4]thiadiazole, C26H18ClFN4S, (II ...
Sadashivamurthy Shamanth +5 more
doaj +1 more source
Inhibition effect of 2-amino-5-ethyl-1, 3, 4-thiadiazole on corrosion behaviour of austenitic stainless steel type 304 in dilute HCl solution [PDF]
, 2016 The corrosion inhibition of type 304 austenitic stainless steel by 2-amino-5-ethyl-1, 3, 4-thiadiazole (TTD) compound and the electrochemical behaviour in dilute HCl solution were investigated through potentiodynamic polarization test, mass loss ...
Fedotova, T. +3 more
core +1 more source
Molecules, 2023 In light of the variety of industrial uses and economic relevance of mild steel, corrosion resistance is a serious topic. Utilization of inhibitors serves as one of the most essential methods for corrosion control.
Ibrahim O. Althobaiti +4 more
doaj +1 more source
Antimicrobial activity, minimum inhibitory concentration and cytotoxicity of thiadiazol compound [PDF]
Romanian Journal of Infectious DiseasesBackground. The azole chemicals category include thiadiazoles which are heterocyclic compounds having sulfur and two nitrogen atoms that have five members. Aim.
Ban M. Saeed +3 more
doaj +1 more source
Benzo[1,2-d:4,5-d′]bis([1,2,3]thiadiazole)-4-carbonitrile
Molbank, 2023 Electron-withdrawing heterocyclic units are found in most organic optoelectronic materials. Benzo[1,2-d:4,5-d′]bis([1,2,3]thiadiazole) is an interesting new heterocyclic system, the chemical properties of which are much less studied than other fused ...
Timofey N. Chmovzh +3 more
doaj +1 more source
A Study of the Corrosion Inhibition of Mild Steel in 0.5M Tetraoxosulphate (VI) acid by Alstonia boonei Leaves Extract as an Inhibitor at Different Temperatures [PDF]
, 2017 A comparative study of the corrosion inhibition performance of Alstonia boonei leaves extract in 0.5M tetraoxosulphate (VI) acid at different temperatures (30ᵒC, 50ᵒC and 70ᵒC) was undertaken.
Elachi, E. E. (Elachi) +3 more
core +1 more source