Results 11 to 20 of about 11,648,543 (253)

PHARMACOLOGICAL ACTIVITY OF 5‐PHENYL‐1: 3: 4‐THIADIAZOLE (L 1538), 2‐AMINO‐5‐PHENYL‐1: 3: 4‐THIADIAZOLE (L 1460) AND 2‐AMINO‐5‐(2‐THIENYL)‐1: 3: 4‐THIADIAZOLE (L 1458) [PDF]

open access: yesBritish Journal of Pharmacology and Chemotherapy, 1958
The pharmacological actions of 5‐phenyl‐1: 3: 4‐thiadiazole (L 1538), 2‐amino‐5‐phenyl‐1: 3: 4‐thiadiazole (L 1460) and 2‐amino‐5‐(2′‐thienyl)‐1: 3: 4‐thiadiazole (L 1458) have been studied and compared with those of other muscular relaxant drugs. The three compounds have paralysing effects in mice, rats, cats, and dogs.
G, MAFFII, E, SONCIN
openaire   +2 more sources

Synthesis and biological evaluation of new 1,3,4-thiadiazole derivatives as potent antimicrobial agents

open access: yesChemical Monthly, 2022
A series of 1,3,4-thiadiazole derivatives were designed and synthesized using N-(4-nitrophenyl)acetohydrazonoyl bromide and 1-[3,5-dimethyl-1-(4-nitrophenyl)-1H-pyrazol-4-yl]ethan-1-one as starting materials.
Monica G. Kamel   +6 more
semanticscholar   +1 more source

Effect of Antibiotic Amphotericin B Combinations with Selected 1,3,4-Thiadiazole Derivatives on RPTECs in an In Vitro Model

open access: yesInternational Journal of Molecular Sciences, 2022
4-(5-methyl-1,3,4-thiadiazole-2-yl) benzene-1,3-diol (C1) and 4-[5-(naphthalen-1-ylmethyl)-1,3,4-thiadiazol-2-yl] benzene1,3-diol (NTBD) are representative derivatives of the thiadiazole group, with a high antimycotic potential and minimal toxicity ...
Agnieszka Dróżdż   +11 more
semanticscholar   +1 more source

Synthesis of some Schiff's bases derivatives from aminoazo compounds

open access: yesمجلة بغداد للعلوم, 2007
Reaction of,2- [( 4- amio phenyl ) diazenyl] 1,3,4- thiadiazole -5- thiol (S1) with p- chlorobenzeldehyde,3,4 – dimethoxy benzaldehyde and pyrrol-2- carbonxaldehyde gave -5- [{4-(4-chlorobenzylidene amino) phenyl} diezenyl]-1,3,4- thiadiazole-2- thiol ...
Baghdad Science Journal
doaj   +1 more source

Pitting Corrosion Inhibition of Type 304 Austenitic Stainless steel by 2�Amino�5�ethyl�1,3,4�thiadiazole in Dilute Sulphuric Acid [PDF]

open access: yes, 2015
The electrochemical behaviour and inhibitor protection of 2 amino 5 ethyl 1,3,4 thiadiazole (TTD) on the pitting corrosion of austenitic stainless steel (type 304) in dilute sulphuric acid solution con taminated with recrystallised sodium chloride was
Loto, C. A., Loto, R. T.
core   +1 more source

Quantum chemical study of heterocyclic organic compounds on the corrosion inhibition [PDF]

open access: yes, 2022
Corrosion damages all materials, necessitating replacement and inspection related expenses. Thus, the demand has increased for new corrosion inhibitor materials.
Mamand, Dyari Mustafa   +3 more
core   +3 more sources

Synthesis and Characterization of Five, Sevene Heterocyclic Membered Rings

open access: yesمجلة بغداد للعلوم, 2013
New compounds containing heterocyclic units have been synthesized. These compounds include 2-amino 5- phenyl-1,3,4-thiadiazole (1) as starting material to prepare the Schiff bases 2N[3-nitrobenzylidene -2 hydroxy benzylidene and 4-N,N-dimethyl ...
Baghdad Science Journal
doaj   +1 more source

Synthesis and structure–activity relationship of L‐methionine‐coupled 1,3,4‐thiadiazole derivatives with activity against influenza virus

open access: yesChemical Biology and Drug Design, 2021
In previous investigations, we identified a class of 1,3,4‐thiadiazole derivatives with antiviral activity. N‐{3‐(Methylsulfanyl)‐1‐[5‐(phenylamino)‐1,3,4‐thiadiazole‐2‐yl]propyl}benzamide emerged as a relevant lead compound for designing novel influenza
Esra Tatar   +5 more
semanticscholar   +1 more source

Preparation of some azo compounds by diazotization and coupling of 2- amino -5 – thiol -1,3,4- thiadizaole

open access: yesمجلة بغداد للعلوم, 2015
2- amino -5- thiol-1,3,4- thiadiazole (S1) was prepared by cyclic locking of thiosemicarbazide in the presence of anhydrous sodium carbonate and CS2. diazotization of (S1) compound gave diazonium salt (S2) that reacts with different activated aromatic ...
Baghdad Science Journal
doaj   +1 more source

Synthesis and Evaluation of the Anti-Microbial Activity of New Heterocycles Containing the 1,3,4-Thiadiazole Moiety

open access: yesMolecules, 2011
A new series of thiadiazole-enaminones 4 were synthesized via reactions of 5-acetyl-1,3,4-thiadiazoles 3 with dimethylformamide-dimethylacetal (DMF-DMA).
Thoraya A. Farghaly   +2 more
doaj   +1 more source

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