4-triazole - Open Access .click

Results 91 to 100 of about 12,908,442 (282)

Self‐Assembled Pt(II) Complexes Boost Up Stem Cell Proliferation and Accelerate Metamorphosis in Living Organisms

Angewandte Chemie, EarlyView.
Pt1, an organometallic platinum‐based complex, act as a modulator of redox homeostasis in cnidarians, regulating cellular functions and life‐cycle dynamics. In Nematostella vectensis, it mitigates oxidative stress, strengthens detox systems and accelerates development.
Giuseppina Tommasini +13 more
wiley +2 more sources

Features of the vegetative state and arterial pressure level in children with chronic gastroduodenal pathology

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2018
Introduction. Heterocyclic compounds are the foundation on which the creation of medicines is successfully carried out. One such system is 1,2,4-triazole and 3-methylxanthine.
A. S. Hotsulia
doaj +1 more source

Structural study and thermal behavior of novel interaction product of 4-amino-5-(furan-2-yl)-4H-1,2,4-triazole-3-thione with molecular iodine

, 2019
As a part of investigation of thyreostatic activity of mercapto-substituted triazoles, the structure, spectroscopic properties of 4-amino-5-(furan-2-yl)-4H-1,2,4-triazole-3-thione were obtained.
Nikolay V. Luanguzov (8102078) +5 more
core +1 more source

Aktivierung von Metallkomplexen durch Ultraschallwellen für eine gezielte Krebstherapie

Angewandte Chemie, EarlyView.
Ultrasound enables non‐invasive activation of metal‐based therapeutics deep within tumors. Acoustic cavitation can drive sonodynamic reactive oxygen species generation or mechanochemical metal–ligand bond dissociation, enabling controlled release of bioactive payloads.
Félix Grosjean +3 more
wiley +1 more source

Metal Free Domino β‑Azidation/[3 + 2] Cycloaddition Reaction for the Synthesis of 1,2,3-Triazole-Fused Dihydrobenzoxazinones

, 2019
A metal free DBU catalyzed synthesis of 1,2,3-triazole-fused dihydrobenzoxazinone derivatives by tandem β-azidation/[3 + 2] cycloaddition reaction has been developed under mild conditions.
Kiranmai Nayani (7148414) +3 more
core +2 more sources

Synthesis of Large‐ and Medium‐Sized Heterobiaryl Atropisomeric Rings and Atropopeptides by Catalytic Intramolecular SNAr

Angewandte Chemie, EarlyView.
Catalytic, intramolecular N‐heterocycle arylation by nucleophilic aromatic substitution (SNAr) is now available for synthesis of highly strained macrocycles and medium‐sized heterobiaryl atropisomeric rings, including atropopeptides. Key to the approach is the ability to generate a strong base catalytically, taking advantage of base‐embedding ...
Alireza Abbasi Kejani +7 more
wiley +2 more sources

Synthesis and structure of some new Schiff bases, derivatives of 2-((4-((R-benzylidene)amino)-5-(2-fluorophenyl)-4H-1,2,4-triazole-3-yl)thio)acetohydrazides

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2018
Triazole derivatives are among wide range of pharmacological agents, such as antimicrobial, analgesic, anti-inflammatory, anticonvulsant, antitumor, antimalarial, antiviral, antiproliferative, anti-cancer drugs etc. The importance of triazole derivatives
Ye. S. Pruglo
doaj +1 more source

Physical-chemical properties of 5-(3-fluorophenyl)-4-amino-1,2,4-triazole-3-thiol s-derivatives

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2017
Introduction. Currently an attempt to combine 1,2,4-triazole heterocycle with various pharmacologically active fragments of other organic molecules is popular among the scientists.
O. A. Bihdan, V. V. Parchenko
doaj +1 more source

Anion-induced structural varieties of Cu^II coordination complexes with 3-phenyl-4-(3-pyridyl)-5-(4-pyridyl)-1,2,4-triazole

, 2019
Two CuII coordination complexes {[Cu(L430)(H2O)2](NO3)2}n (I) and {[Cu(L430)2(H2O)2](ClO4)2(H2O)0.3}n (II) have been synthesized based on 3-phenyl-4-(3-pyridyl)-5-(4-pyridyl)-1,2,4-triazole (L430) in the presence of different anions (CIF file CCDC nos ...
Si Wang (519067), Na Wu (240778), Jing Chen (4762) +2 more
core +1 more source

Design and Synthesis of Novel 3‑Nitro‑1H‑1,2,4-triazole-1,2,3-triazole-1,4-disubstituted Analogs as Promising Antitrypanosomatid Agents: Evaluation of In Vitro Activity against Chagas Disease and Leishmaniasis

A series of 28 compounds, 3-nitro-1H-1,2,4-triazole, were synthesized by click-chemistry with diverse substitution patterns using medicinal chemistry approaches, such as bioisosterism, Craig-plot, and the Topliss set with excellent yields.
Carla C. P. Arruda (15367833) +20 more
core +2 more sources

3. good health
1 2 4-triazole
chemistry

synthesis
triazoles
physical-chemical properties

a1
1,2,3-triazole
b2