Results 81 to 90 of about 9,352,447 (290)

Precision Switching and Coupled Motion in a [3]Rotaxane Molecular Machine

open access: yesAngewandte Chemie, EarlyView.
A [3]rotaxane, composed by two crown ether macrocycles and an axle presenting three recognition sites, is operated through both chemical and electrochemical stimuli. The position of the macrocycles is precisely controlled by sequential stimulation and the processes are fully reversible. The characterization of the system revealed the macrocycles affect
Leonardo Andreoni   +3 more
wiley   +2 more sources

Synthesis of ylidene derivatives of 4-amino-5-(4-tert-butylphenyl)-4H-1,2,4-triazole-3-thiol

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2015
Aim. Modern medicine widely applies drugs from the group of 1,2,4-triazole (fluconazole, triazolam, alprazolam, letrozole and others) in the practice.
I. I. Aksionova   +2 more
doaj   +1 more source

Estudo computacional de complexos mononucleares de cobre (II) e zinco (II) com ligantes triazólicos [PDF]

open access: yes, 2013
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas, Programa de Pós-Graduação em Química, Florianópolis, 2013.Neste trabalho foram estudados complexos mononucleares de cobre(II) ou zinco(II ...
Fonseca, David Edson Pedrosa
core  

Auf dem Weg zu chromoselektiven Transformationen in biologischen Systemen: Perspektiven und Herausforderungen

open access: yesAngewandte Chemie, EarlyView.
Die Kontrolle biologischer Systeme mit organischen Chromophoren hat sich zu einer vielversprechenden Strategie entwickelt und findet Anwendung von der chemischen Biologie bis hin zur Medizin. Die Komplexität von In‐vivo‐Systemen lässt sich jedoch nicht mit nur einer einzigen Lichtwellenlänge adäquat abbilden.
Nadja A. Simeth
wiley   +1 more source

Phosphoryl Radicals from Trivalent Iminyl Phosphines: A Photocatalytic Approach to N‐Phosphoryl Azetidines

open access: yesAngewandte Chemie, EarlyView.
Photochemically generated phosphoryl radicals from iminyl phosphines enable strain‐release addition to azabicyclobutanes, providing access to elusive N‐phosphoryl azetidines. Combined experimental, computational, and EPR studies reveal an unconventional water‐assisted photoredox pathway.
Chandu G. Krishnan   +4 more
wiley   +2 more sources

2H‑1,2,3-Triazole-Based Dipeptidyl Nitriles: Potent, Selective, and Trypanocidal Rhodesain Inhibitors by Structure-Based Design [PDF]

open access: yes, 2018
Macrocyclic inhibitors of rhodesain (RD), a parasitic cysteine protease and drug target for the treatment of human African trypanosomiasis, have shown low metabolic stability at the macrocyclic ether bridge.
Saint-Auret, Sarah   +32 more
core   +1 more source

Synthesis and antimicrobial evaluation of spiro compound containing 1,2,4-triazole and isatin

open access: yesOrbital: The Electronic Journal of Chemistry, 2011
The synthesis of 6'-Phenyl-4'-thioxo-3'-(4H-1,2,4-triazole-4-yl)-3',4'-dihydrospiro [Indoline-3,2'-[1,3,5]oxadiazine]-2-one (5a-h) is carried out by two a step reaction, beginning with acid catalyzed condensation of 4H-1,2,4-triazole-4-amine (1)
Visha P. Modi   +2 more
doaj   +1 more source

4-(4-Methoxyphenethyl)-3,5-diphenyl-4H-1,2,4-triazole

open access: yesActa Crystallographica Section E, 2012
In the title compound, C23H21N3O, the dihedral angles formed by the mean plane of the triazole ring [maximum deviation = 0.007 (1) Å] and the three phenyl rings are 51.13 (8), 52.84 (8) and 47.04 
G. Anuradha   +3 more
doaj   +1 more source

Cu(OTf)2-Catalyzed 1,2,3-triazole-ring-controlled selective phenolic O–H bond methylthiomethylation [PDF]

open access: yes, 2019
Copper-catalyzed selective methylthiomethylation of 1,4-disubstituted 1,2,3-triazole phenols using DMSO as a methylthiomethylation reagent was achieved.
Weigen Du (6918761)   +4 more
core   +1 more source

Funktionalisierung von Peptiden auf der festen Phase im späten Synthesestadium

open access: yesAngewandte Chemie, EarlyView.
Peptidmodifikationen sind für die Kontrolle der Eigenschaften von Peptidwirkstoffen von entscheidender Bedeutung. Daher sind Strategien, die einen effizienten und schnellen Einbau nicht‐kanonischer Modifikationen in Peptide in Parallelformaten ermöglichen, sehr gefragt.
Marius Werner   +2 more
wiley   +1 more source

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