Results 81 to 90 of about 9,352,447 (290)
Precision Switching and Coupled Motion in a [3]Rotaxane Molecular Machine
A [3]rotaxane, composed by two crown ether macrocycles and an axle presenting three recognition sites, is operated through both chemical and electrochemical stimuli. The position of the macrocycles is precisely controlled by sequential stimulation and the processes are fully reversible. The characterization of the system revealed the macrocycles affect
Leonardo Andreoni +3 more
wiley +2 more sources
Synthesis of ylidene derivatives of 4-amino-5-(4-tert-butylphenyl)-4H-1,2,4-triazole-3-thiol
Aim. Modern medicine widely applies drugs from the group of 1,2,4-triazole (fluconazole, triazolam, alprazolam, letrozole and others) in the practice.
I. I. Aksionova +2 more
doaj +1 more source
Estudo computacional de complexos mononucleares de cobre (II) e zinco (II) com ligantes triazólicos [PDF]
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas, Programa de Pós-Graduação em Química, Florianópolis, 2013.Neste trabalho foram estudados complexos mononucleares de cobre(II) ou zinco(II ...
Fonseca, David Edson Pedrosa
core
Die Kontrolle biologischer Systeme mit organischen Chromophoren hat sich zu einer vielversprechenden Strategie entwickelt und findet Anwendung von der chemischen Biologie bis hin zur Medizin. Die Komplexität von In‐vivo‐Systemen lässt sich jedoch nicht mit nur einer einzigen Lichtwellenlänge adäquat abbilden.
Nadja A. Simeth
wiley +1 more source
Photochemically generated phosphoryl radicals from iminyl phosphines enable strain‐release addition to azabicyclobutanes, providing access to elusive N‐phosphoryl azetidines. Combined experimental, computational, and EPR studies reveal an unconventional water‐assisted photoredox pathway.
Chandu G. Krishnan +4 more
wiley +2 more sources
2H‑1,2,3-Triazole-Based Dipeptidyl Nitriles: Potent, Selective, and Trypanocidal Rhodesain Inhibitors by Structure-Based Design [PDF]
Macrocyclic inhibitors of rhodesain (RD), a parasitic cysteine protease and drug target for the treatment of human African trypanosomiasis, have shown low metabolic stability at the macrocyclic ether bridge.
Saint-Auret, Sarah +32 more
core +1 more source
Synthesis and antimicrobial evaluation of spiro compound containing 1,2,4-triazole and isatin
The synthesis of 6'-Phenyl-4'-thioxo-3'-(4H-1,2,4-triazole-4-yl)-3',4'-dihydrospiro [Indoline-3,2'-[1,3,5]oxadiazine]-2-one (5a-h) is carried out by two a step reaction, beginning with acid catalyzed condensation of 4H-1,2,4-triazole-4-amine (1)
Visha P. Modi +2 more
doaj +1 more source
4-(4-Methoxyphenethyl)-3,5-diphenyl-4H-1,2,4-triazole
In the title compound, C23H21N3O, the dihedral angles formed by the mean plane of the triazole ring [maximum deviation = 0.007 (1) Å] and the three phenyl rings are 51.13 (8), 52.84 (8) and 47.04 
G. Anuradha +3 more
doaj +1 more source
Cu(OTf)2-Catalyzed 1,2,3-triazole-ring-controlled selective phenolic O–H bond methylthiomethylation [PDF]
Copper-catalyzed selective methylthiomethylation of 1,4-disubstituted 1,2,3-triazole phenols using DMSO as a methylthiomethylation reagent was achieved.
Weigen Du (6918761) +4 more
core +1 more source
Funktionalisierung von Peptiden auf der festen Phase im späten Synthesestadium
Peptidmodifikationen sind für die Kontrolle der Eigenschaften von Peptidwirkstoffen von entscheidender Bedeutung. Daher sind Strategien, die einen effizienten und schnellen Einbau nicht‐kanonischer Modifikationen in Peptide in Parallelformaten ermöglichen, sehr gefragt.
Marius Werner +2 more
wiley +1 more source

