Results 121 to 130 of about 12,908,442 (282)

Aza‐Büchner–Curtius–Schlotterbeck Reaction Enables Selective Construction of Quaternary Carbon Centers

Angewandte Chemie International Edition, EarlyView.
We introduce the Aza‐Büchner–Curtius–Schlotterbeck (ABCS) reaction: A mild, catalyst‐free method for homologating aryl imines. Diverging from the traditional BCS mechanism, the diazo intermediate undergoes selective C─C insertion to form an all‐carbon quaternary center.
Simon O. Angerer, Vincent George, Aryaman Pattanik, Gaia Carpentiero, Tereza Morcinková, Julia Rehbein, Burkhard König   +6 more
wiley   +1 more source

Activation of Metal Complexes With Ultrasound Waves for Targeted Anticancer Therapy

Angewandte Chemie International Edition, EarlyView.
Ultrasound enables non‐invasive activation of metal‐based therapeutics deep within tumors. Acoustic cavitation can drive sonodynamic reactive oxygen species generation or mechanochemical metal–ligand bond dissociation, enabling controlled release of bioactive payloads.
Félix Grosjean, Nicolás Montesdeoca, Gilles Berger, Johannes Karges   +3 more
wiley   +1 more source

Corrosion inhibition of brass 60Cu-40Zn in 3% NaCl solution by 3-amino-1, 2, 4-triazole-5-thiol. [PDF]

Heliyon, 2020
Damej M, Chebabe D, Abbout S, Erramli H, Oubair A, Hajjaji N.   +5 more
europepmc   +1 more source

Synthesis and biological evaluation of selective phosphonate-bearing 1,2,3-triazole-linked sialyltransferase inhibitors

, 2021
The critical role of sialyltransferase (ST) enzymes in tumour cell growth and metastasis, as well as links to multi-drug and radiation resistance, has seen STs emerge as a target for potential antimetastatic cancer treatments.
Andrew P Montgomery (20254962), Haibo Yu (273911), Danielle Skropeta (2662507), Christopher Dobie (17754743), Rémi Szabo (20165334)   +4 more
core  

A Ruthenium(CAAC‐5) Olefin Metathesis Catalyst for Bioconjugation

Angewandte Chemie International Edition, EarlyView.
The aqueous instability of ruthenium catalysts restricts olefin metathesis in biological media. A Ru(CAAC‐5) complex bearing an aniline handle is reported that remains active under biologically relevant conditions and enables bioconjugation to proteins, peptides, and an artificial metalloenzyme, providing a robust platform for olefin metathesis in ...
Damian Alexander Graf, Mikhail Boym, María Álvarez, Tsvetan Kardashliev, Thomas R. Ward   +4 more
wiley   +1 more source

1,2,4-Triazole-3,5-diylidene:  A Building Block for Organometallic Polymer Synthesis

, 2016
1,2,4-Triazole-3,5-diylidene:  A Building Block for Organometallic Polymer ...
Olivier Guerret (2728345), Stéphane Solé (2990865), Georges Trinquier (1886878), Heinz Gornitzka (1385718), Markus Teichert (2975172), Guy Bertrand (1453126)   +5 more
core   +1 more source

Structure-activity relationships for NAMI-A-type complexes (HL)[trans-RuCl4L(S-dmso)ruthenate(III)] (L = imidazole, indazole, 1,2,4-triazole, 4-amino-1,2,4-triazole, and 1-methyl-1,2,4-triazole): Aquation, redox properties, protein binding, and antiproliferative activity

, 2007
Imidazolium [trans-tetrachloro(1H-imidazole)(S-dimethylsulfoxide) ruthenate(III)] (NAMI-A) and indazolium [trans-tetrachlorobis(1H-indazole) ruthenate(III)] (KP1019) are the most promising ruthenium complexes for anticancer chemotherapy.
Timerbaev, Andrei R., Jakupec, Michael A., Arion, Vladimir B., Reisner, Erwin, Eichinger, Rene, Semenova, Olga, Grössl, Michael, Groessl, Michael, Keppler, Bernhard K., Hartinger, Christian G.   +9 more
core   +1 more source

The synthesis of [1,2,3]-triazole-based bent core liquid crystals via microwave-mediated ‘Click Reaction’ and their mesomorphic behaviour

, 2019
A series of [1,2,3]-triazole-based liquid crystal compounds were synthesised via a fast and efficient microwave-mediated ‘Click Reaction’ and their phase behaviour is presented.
Samuel Sprunt (2529220), Kunlun Wang (2794564), Robert J. Twieg (567348)   +2 more
core   +1 more source

1-(4-chlorophenyl)triazole

, 2014
This dataset contains experimental data from a sample (1-(4-chlorophenyl)triazole, InChI=1S/C8H6ClN3/c9-7-1-3-8(4-2-7)12-6-5-10-11-12/h1-6H). The datasets from the following experiments are available: thin-layer chromatography ...
Hafner, Andreas
core   +1 more source

A Portal‐Preorganized Cucurbit[7]uril‐Ruthenium Conjugate Enables Motif‐Selective Protein Sensing

Angewandte Chemie International Edition, EarlyView.
Reprogramming cucurbit[7]uril (CB7) recognition through portal engineering transforms an optically silent host into a motif‐selective photoluminescent receptor. The portal‐preorganized CB7‐Rubpy conjugate directly reports changes in aromatic motif accessibility, enabling optical sensing of protein misfolding and refolding.
Patrick Gruhs, Albert Kraft, Vahideh Mahram, Marco Neumaier, Papri Chakraborty, Emily Janz, Maria Vittoria Balli, Pierre Picchetti, Luca Prodi, Manfred Kappes, Frank Biedermann   +10 more
wiley   +1 more source