Results 131 to 140 of about 12,908,442 (282)

STUDY OF THE PROTONATION OF 1, 2, 4-TRIAZOLE. DFT CALCULATIONS

Vìsnik Dnìpropetrovsʹkogo unìversitetu. Serìâ Hìmìâ
У цій роботі досліджена реакція між 1,2,4-тріазолом і хлоридною кислотою (HCl) з метою синтезу протонованого 1,2,4-тріазолу (TAH+). Ми використовували розрахунки теорії функціоналу густини (DFT), щоб отримати уявлення про структурний аналіз молекули. Кілька дескрипторів реакційної здатності, включаючи спорідненість до електрона, різниця енергій HOMO ...
El Addali, Abdelahad, El-Kiri, Zakaryae, El Boukili, Abdellah, Saufi, Hamid, Boudad, Lahcen   +4 more
openaire   +2 more sources

A study of the inhibition of catalase by 3-amino-1:2:4-triazole [PDF]

Biochemical Journal, 1958
E, MARGOLIASH, A, NOVOGRODSKY
openaire   +2 more sources

Synthesis, Crystal Structure, EXAFS, and Magnetic Properties of catena-Poly[μ-tris(4-(2-hydroxyethyl)-1,2,4-triazole-N¹,N²)copper(II)] Diperchlorate Trihydrate:  Relevance with the Structure of the Iron(II) 1,2,4-Triazole Spin Transition Molecular Materials

, 2016
[Cu(hyetrz)3](ClO4)2·3H2O (hyetrz = 4-(2-hydroxyethyl)-1,2,4-triazole) represents the first structurally characterized metal(II) chain compound containing triple N1,N2-1,2,4-triazole bridges. The structure has been solved at 298 K by single-crystal X-ray
Yann Garcia (1727962), Philippe Guionneau (1904971), Jacques Moscovici (2975865), Georges Bravic (2658685), Katia Lambert (2975859), Petra J. van Koningsbruggen (1997050), Alain Michalowicz (2658709), Olivier Kahn (2961741), Daniel Chasseau (2658682), Giovanni Luca Cascarano (2975862)   +9 more
core   +1 more source

Click‐to‐Release Reactivity of Quaternary Anilinium Tetrazines Enables Cascade Assembly of Multifunctional Biomolecular Scaffolds

Angewandte Chemie International Edition, EarlyView.
Click chemistry has evolved from making covalent connections to also breaking bonds. Here, a cascade assembly is reported that combines these maneuvers to build multifunctional biomolecular scaffolds in a modular one‐pot reaction. The unifying azide release‐tetrazine hub clicks with a trans‐cyclooctene tag, rapidly liberates N,N‐dimethylaniline to ...
Markus Staudt, Christian B. M. Poulie, Andreas Löffler, Peter R. Meinig, Riley J. Deutsch‐Williams, Barbara Herrmann, Ralph Weissleder, Hannes Mikula, Jonathan C. T. Carlson, Matthias M. Herth   +9 more
wiley   +1 more source

Use of Clotrimazole in Finfish Aquaculture: Mechanistic Insights, Limitations, and Future Directions for Antifungal Therapy

Animal Research and One Health, EarlyView.
This review critically evaluates clotrimazole as a potential antifungal for finfish aquaculture, highlighting strong mechanistic and in vitro efficacy against aquatic mycoses alongside major gaps in in vivo evidence, toxicokinetics, residue safety, and environmental risk, outlining priorities for responsible therapeutic development and regulatory ...
Arya Sen, Debashri Mondal, Thangapalam Jawahar Abraham   +2 more
wiley   +1 more source

Mild C─F Activation of Azido(per)Fluoroalkanes

Chemistry – A European Journal, EarlyView.
Mild and selective activation of C(sp3)–F bonds in azido(per)fluoroalkanes using thiolates was developed, leading to novel functionalized azides. The reaction is initiated by nucleophilic attack of the sulfur atom to the terminal nitrogen of the azido group, followed by fluoride ion elimination.
Olena Shaitanova, María Martínez Mallo, Sergii Suikov, Blanka Klepetářová, Josef Filgas, Petr Slavíček, Lucie Bednárová, Petr Beier   +7 more
wiley   +1 more source

Hybrid Macrocyclic Peptides — Synthetic Strategies to Diversify and Cyclize Peptide Libraries in Phage Display Selections

Chemistry – A European Journal, EarlyView.
Hybrid macrocyclic peptides unite genetically encoded peptide libraries with the structural complexity of synthetic small molecules. This Review critically analyzes phage‐compatible cyclization and diversification chemistries, highlights emerging opportunities beyond traditional cysteine‐based approaches, and outlines how future advances may enable the
Titia Rixt Oppewal, Clemens Mayer
wiley   +1 more source

Chiral Pyrazolinylidene Complexes for Asymmetric Catalysis

Chemistry – A European Journal, EarlyView.
The synthesis and application of pyrazolin‐5‐ylidene NHC chiral‐at‐ruthenium catalysts is reported. The strong donating pyrazolin‐5‐ylidene ligands led to highly electron rich ruthenium complexes, which showed excellent catalytic activity and enantioselectivity in the intramolecular aziridination of an alkene.
Felix Möller, Nemrud Demirel, Thomas Krüger, Linus Plohnke, Jennifer Schröder, Sergei I. Ivlev, Eric Meggers   +6 more
wiley   +1 more source

Design, Synthesis and Biophysical Characterisation of CPP-PNA Conjugates for Targeting Oncogenic microRNA-221. [PDF]

J Pept Sci
Cell‐penetrating peptide‐peptide nucleic acid (CPP‐PNA) conjugates that target the oncogenic microRNA‐221‐5p were synthesised using Cu(I)‐catalysed azide‐alkyne cycloaddition (CuAAC) and disulfide‐mediated conjugation strategies. These constructs form highly stable, sequence‐selective PNA/RNA heteroduplexes and demonstrate preliminary antiproliferative
Rotondo M, Illien F, Burlina F, Biondi B.   +3 more
europepmc   +2 more sources

Anion‐Selective Channels Formed by Synthetic 13‐Mer Chimeric α ‐Peptide‐Oligourea Foldamers

Chemistry – A European Journal, EarlyView.
Synthetic 13‐mer α‐peptide‐oligourea chimeric foldamers self‐assemble into supramolecular ion channels, demonstrating high ion transport activity with distinct anion selectivity in lipid membranes. This study supports the design of bioinspired functional foldamer‐based channels for synthetic ion transport applications.
Chiranjit Dutta, Dandan Su, Pannaga Krishnamurthy, Zhaoxing Li, Jianwei Li, Morgane Pasco, Min Luo, Mihail Barboiu, Gilles Guichard, R. Manjunatha Kini, Prakash Kumar   +10 more
wiley   +1 more source