Results 21 to 30 of about 12,456,978 (213)

Contemporary notions on the role of 5'-nucleotidase in pregnancy

open access: yesRussian Open Medical Journal, 2022
The review aimed at pooling together available information on 5'-nucleotidase – an enzyme hydrolyzing ribo- and deoxyribonucleoside-5'-monophosphates. The most important product of 5'-nucleotidase activity is adenosine.
Inna V. Dovzhikova   +1 more
doaj   +1 more source

Comparative Study of 5’- Nucleotidase Test in Various Liver Diseases [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2016
Introduction: The liver regulates many important metabolic functions. The 5’-nucleotidase activity is increased in obstructive jaundice, parenchymal liver disease, and hepatic metastases. Aim: This study was conducted to assess the serum levels of 5’-
Mohd Azam Hyder   +2 more
doaj   +1 more source

Serum 5-Nucleotidase [PDF]

open access: yesNature, 1952
REIS1–4 has demonstrated the presence of a phosphatase in various tissues specifically hydrolysing 5-nucleotides, for example, adenosine-5-phosphate. One of us has previously reported5 that normal blood serum has a low 5-nucleotidase activity corresponding to about 1/10 of its non-specific alkaline phosphatase activity towards glycerophosphate. In bone
T F, DIXON, M, PURDON
openaire   +3 more sources

Evaluation of the level of 5'-nucleotidase and some biochemical parameters in the sera of beta-thalassemia patients

open access: yesTikrit Journal of Pure Science, 2023
One of the hydrolytic enzymes that catalyzes the hydrolysis of 5' -nucleotides into ribonucleosides and phosphate is the 5'nucleotidase, which is found in several organs.
Sameer M. Al-Gorany   +1 more
doaj   +1 more source

Effects of physical exercise on the functionality of human nucleotidases: A systematic review

open access: yesPhysiological Reports, 2022
Nucleotidases contribute to the regulation of inflammation, coagulation, and cardiovascular activity. Exercise promotes biological adaptations, but its effects on nucleotidase activities and expression are unclear.
Cesar Eduardo Jacintho Moritz   +5 more
doaj   +1 more source

AIF1+CSF1R+ MSCs, induced by TNF‐α, act to generate an inflammatory microenvironment and promote hepatocarcinogenesis

open access: yesHepatology, EarlyView., 2022
Mesenchymal stem cells subset, educated by TNF‐α, are involved to generate inflammatory microenvironment and promote hepatocarcinogenesis Abstract Background and Aims Increasing evidence suggests that mesenchymal stem cells (MSCs) home to injured local tissues and the tumor microenvironment in the liver.
Chen Zong   +9 more
wiley   +1 more source

Extracellular Vesicles from Bothrops jararaca Venom Are Diverse in Structure and Protein Composition and Interact with Mammalian Cells

open access: yesToxins, 2022
Snake venoms are complex cocktails of non-toxic and toxic molecules that work synergistically for the envenoming outcome. Alongside the immediate consequences, chronic manifestations and long-term sequelae can occur. Recently, extracellular vesicles (EVs)
Larissa Gonçalves-Machado   +7 more
doaj   +1 more source

Estradiol regulation of nucleotidases in female reproductive tract epithelial cells and fibroblasts. [PDF]

open access: yesPLoS ONE, 2013
The use of topical and oral adenosine derivatives in HIV prevention that need to be maintained in tissues and cells at effective levels to prevent transmission prompted us to ask whether estradiol could influence the regulation of catabolic nucleotidase ...
Zheng Shen   +7 more
doaj   +1 more source

Ecto-5′-nucleotidase (CD73) attenuates inflammation after spinal cord injury by promoting macrophages/microglia M2 polarization in mice

open access: yesJournal of Neuroinflammation, 2018
Immune activation, specifically activation of macrophages and resident microglia, leading to inflammation is a key component in the progression of spinal cord injury (SCI).
Shun Xu   +11 more
semanticscholar   +1 more source

Expression of major ectonucleotidases after cortical stab brain injury in rats: A real-time PCR study [PDF]

open access: yesArchives of Biological Sciences, 2014
Ectonucleotidases are cell surface-located enzymes responsible for the extracellular degradation of nucleotides. They are comprised of several protein families: ectonucleoside triphosphate diphosphohydrolases (E-NTPDase), ectonucleotide ...
Parabucki Ana   +6 more
doaj   +1 more source

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