Results 101 to 110 of about 5,174,697 (237)

Structural analysis of the NifL‐NifA complex reveals the molecular basis of anti‐activation of nitrogen fixation gene expression in Azotobacter vinelandii

The FEBS Journal, EarlyView.
Using cryo‐EM combined with biochemical and genetic approaches, we mapped the interaction surface between NifL and NifA to gain insights into the regulation of nitrogen fixation genes in A. vinelandii. Our findings suggest that NifL, a homolog of histidine kinases lacking phosphorylation activity, evolved to act as a steric block of NifA activity ...
Marcelo Bueno Batista, Jake Richardson, Michael W. Webster, Dmitry Ghilarov, John W. Peters, David M. Lawson, Ray Dixon   +6 more
wiley   +1 more source

Effects of 5-Aminolevulinic Acid as a Supplement on Animal Performance, Iron Status, and Immune Response in Farm Animals: A Review

Animals, 2020
Simple Summary 5-aminolevulinic acid is an amino acid that promotes the formation of heme—an essential constituent of hemoglobin. It has been recently used as a novel feed supplement to enhance the productivity of farm animals, but the current ...
A. O. Hendawy, M. Khattab, S. Sugimura, Kan Sato   +3 more
semanticscholar   +1 more source

Topical photodynamic therapy using different porphyrin precursors leads to differences in vascular photosensitization and vascular damage in normal mouse skin [PDF]

, 2014
Different distributions of hexyl aminolevulinate (HAL), aminolevulinic acid (ALA) and methyl aminolevulinate (MAL) in the superficial vasculature are not well studied but they are hypothesized to play an important role in topical photodynamic therapy ...
Bruijn, H.S. (Riette) de, Haas, E.R.M. (Ellen) de, Middelburg, T.A. (Tom), Neumann, H.A.M. (Martino), Ploeg-van den Heuvel, A. (Angélique) van der, Robinson, D.J. (Dominic), Vijlder, H.C. (Hanke) de   +6 more
core   +1 more source

Plastid Engineering for Photosynthesis‐Driven Synthesis of Hyaluronic Acid in Tobacco

Plant Biotechnology Journal, EarlyView.
ABSTRACT Hyaluronic acid (HA) is a glycosaminoglycan composed of alternating units of N‐acetylglucosamine and glucuronic acid. High moisture retention, viscoelasticity and biocompatibility are unique features that make HA polymers attractive compounds for medical applications and aesthetic purposes.
Amanda Lopes, Omar Sandoval‐Ibáñez, Stéphanie Arrivault, David Rolo, F. Vanessa Loiacono, Alexander Erban, Daniel Karcher, Stephan Obst, Stephanie Ruf, Joachim Kopka, Ralph Bock   +10 more
wiley   +1 more source

MR-guided Focused Ultrasound Facilitates Sonodynamic Therapy with 5-Aminolevulinic Acid in a Rat Glioma Model

Scientific Reports, 2019
Glioblastoma multiforme (GBM) continues to have a dismal prognosis and significant efforts are being made to develop more effective treatment methods. Sonodynamic therapy (SDT) is an emerging modality for cancer treatment which combines ultrasound with ...
Sheng‐Kai Wu, Marc A. Santos, S. Marcus, K. Hynynen   +3 more
semanticscholar   +1 more source

Acute Intermittent Porphyria: Pathophysiology and Treatment [PDF]

, 1984
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90337/1/j.1875-9114.1984.tb03340.x ...
Anderson, Badawy, Battersby, Berman, Bickers, Bonkowsky, Bonkowsky, Bonkowsky, Bonkowsky, Bonkowsky, Bottomley, Cavanagh, Cowger, Dhar, Dhar, Disler, Doss, Douer, Eales, Eales, Elsman, Eyck, Felsher, Giger, Granick, Granick, Hanstein, Hellman, Heubel, Kappas, Kappas, Lamon, Lamon, Liem, Ludwig, Magnussen, Magnussen, Massey, Matteis, Mauzerall, McColl, McColl, Menawat, Moore, Moore, Morris, Muller-Eberhard, Muller-Eberhard, Muller-Eberhard, Mustajoki, Nielsen, Nyman, Ohnhaus, Parikh, Pass, Perlroth, Peterson, Reynolds, Ridley, Rifkind, Rizk, Rose, Snyder, Stein, Strand, Sweeny, Tait, Treece, Tschudy, Tschudy, Tschudy, Verneuil, Watson, Watson, Watson, Welland, Wetterberg   +76 more
core   +1 more source

Immunomodulatory effects of photodynamic therapy for skin cancer: Potential strategies to improve treatment efficacy and tolerability

Photochemistry and Photobiology, EarlyView.
Photodynamic therapy (PDT) is a nonscarring treatment modality that is widely used for skin cancers and early squamous precursor lesions. PDT was previously thought to work primarily by killing cancer cells directly (via apoptosis or necrosis). However, more recent work indicates that a significant mechanism for PDT is the stimulation of anti‐cancer ...
Mark P. Ortenzio, Sanjay Anand, Jeffrey B. Travers, Edward V. Maytin, Craig A. Rohan   +4 more
wiley   +1 more source

5-Aminolevulinic Acid (ALA) Alleviated Salinity Stress in Cucumber Seedlings by Enhancing Chlorophyll Synthesis Pathway

Frontiers in Plant Science, 2018
5-Aminolevulinic acid (ALA) is a common precursor of tetrapyrroles as well as a crucial growth regulator in higher plants. ALA has been proven to be effective in improving photosynthesis and alleviating the adverse effects of various abiotic stresses in ...
Yue-xuan Wu, Xin Jin, W. Liao, L. Hu, M. M. Dawuda, Xingjie Zhao, Zhongqi Tang, Tingyu Gong, Jihua Yu   +8 more
semanticscholar   +1 more source

Photodynamische Therapie (PDT) und wassergefiltertes Infrarot A (wIRA) bei Patienten mit therapierefraktären vulgären Hand- und Fußwarzen [PDF]

, 2005
Background: Common warts (verrucae vulgares) are human papilloma virus (HPV) infections with a high incidence and prevalence, most often affecting hands and feet, being able to impair quality of life.
Bankova, Lora, Elsner, Peter, Fluhr, Joachim Wilhelm, Fuchs, Silke M., Hoffmann, Gerd, Tittelbach, Jörg   +5 more
core  

Photodynamic priming (PDP) targets platinum resistance from chronic perfluoroalkyl substances (PFAS) exposure in ovarian cancer cells

Photochemistry and Photobiology, EarlyView.
PFAS are environmental contaminants that induce chemoresistance in ovarian cancer cells. This study evaluated BPD‐PDP or ALA‐PpIX‐PDP in combination with carboplatin or doxorubicin to overcome PFAS‐induced chemoresistance in two cell cohorts: (i) PFAS chronically‐exposed and (ii) PFAS outgrown cells (which underwent a “recovery period” after chronic ...
Brittany P. Rickard, Meghan M. Dillon, Lauren A. Sapienza‐Lundie, Suzanne E. Fenton, Imran Rizvi   +4 more
wiley   +1 more source