Results 81 to 90 of about 13,836,694 (159)

Synthesis of 5-aminolevulinic acid derivatives for photodynamic therapy

, 2012
The aim of the thesis was to synthesize a new derivative of 5-aminolevulinic acid, a prodrug used in current photodynamic therapy of cancer. To improve the bioavailability of 5-aminolevulinic acid the new derivative is conceived as an ester instead of an
Miceli, Claudia
core  

Influence of 5-Aminolevulinic Acid and Red Light on Collagen Metabolism of Human Dermal Fibroblasts

, 2003
Patients with localized scleroderma receiving topical photodynamic therapy with 5-aminolevulinic acid show a reduction in skin tightness, suggesting that this therapy reduces skin sclerosis.
Landthaler, Michael, Karrer, Sigrid, Weiderer, Petra, Szeimies, Rolf-Markus, Bosserhoff, Anja Kathrin   +4 more
core   +1 more source

Biallelic pathogenic hydroxymethylbilane synthase gene variants of a neurodegenerative disorder with progressive cystic leukoencephalopathy: a case report

Journal of Medical Case Reports
Background Heterozygous mutations of the hydroxymethylbilane synthase gene can lead to acute intermittent porphyria, with episodic abdominal pain and neuropsychiatric symptoms.
Gabriel Schacht, Miriam Elbracht, Anna-Elisabeth Minder, Thomas Stauch, Arzu Stoppe, Eva Lausberg, Martin Häusler   +6 more
doaj   +1 more source

Protoporphyrin IX-Dependent Antiviral Effects of 5-Aminolevulinic Acid against Feline Coronavirus Type II

Viruses
5-Aminolevulinic acid (5-ALA), a non-proteinogenic amino acid, is an intermediate in the biosynthesis of heme and exerts antiviral effects against feline coronavirus (FCoV); however, the underlying mechanisms remain unclear.
Tomoyoshi Doki, Junna Shimada, Misa Tokunaga, Kaito To, Koichi Orino, Tomomi Takano   +5 more
doaj   +1 more source

Some reactions of 5-aminolevulinic acid with cyclic beta-diketones

, 1998
5-Aminolevulinic acid reacts, under acidic conditions, with cyclohexane-1,3-diones to give 3-(2'-carboxyethyl)tetrahydroindol-4-ones which were characterised, in part, by 2D NMR spectroscopy.
Brown, E H, Butler, A R
core   +2 more sources

aminolevulinic acid marked glioblastoma detection

, 2014
Photobleaching behavior of protoporphyrin IX during 5-aminolevulinic acid marked glioblastoma ...
Neda Haj-hosseini, Johan Richtera, Karin Wårdell, Stefan Andersson-engels   +3 more
core  

ALA Promotes Sucrose Accumulation in Early Peach Fruit by Regulating SPS Activity

Current Issues in Molecular Biology
5-Aminolevulinic acid (ALA), as a novel plant growth regulator, is a critical precursor for the biosynthesis of porphyrin compounds in all organisms. Many studies have reported that exogenous ALA treatment could improve fruit sweetness.
Zheng Chen, Xin Guo, Jinhua Du, Mingliang Yu   +3 more
doaj   +1 more source

The assessment of 5-aminolevulinic acid photodynamic therapy in glioblastomas

Oncologie
Photodynamic therapy (PDT) using 5-aminolevulinic acid (5-ALA) has emerged as a promising strategy in the treatment of various cancers, particularly gliomas.
Aebisher David, Mytych Wiktoria, Łoś Aleksandra, Dynarowicz Klaudia, Myśliwiec Angelika, Bartusik-Aebisher Dorota   +5 more
doaj   +1 more source

5-Aminolevulinic acid-mediated protoporphyrin IX accumulation in the tumor microenvironment of glioma and its implications for 5-aminolevulinic acid-based local tumor therapies: A review of the literature. [PDF]

Neuro Oncol
Özdemir Z, Gallus M, Müther M, Stummer W.   +3 more
europepmc   +1 more source

Radiodynamic Therapy Using Local Administration of 5-Aminolevulinic Acid for <i>In Vivo</i> Osteosarcoma Xenograft Model. [PDF]

In Vivo
Tanemura Y, Nakamura T, Matsuyama Y, Hagi T, Date H, Iino T, Hasegawa M.   +6 more
europepmc   +1 more source