Results 41 to 50 of about 5,174,697 (237)

Photodynamic inactivation of Klebsiella pneumoniae biofilms and planktonic cells by 5-aminolevulinic acid and 5-aminolevulinic acid methyl ester [PDF]

, 2016
The treatment of Klebsiella pneumoniae, particularly extended-spectrum β-lactamase (ESBL)-producing K. pneumoniae, is currently a great challenge. Photodynamic antimicrobial chemotherapy is a promising approach for killing antibiotic-resistant bacteria ...
Han, L, Ishaq, HM, Lei, J, Liu, C, Nair, SP, Wang, L, Xu, J, Zhou, Y   +7 more
core   +1 more source

5-Aminolevulinic acid-guided resection improves the overall survival of patients with glioblastoma—a comparative cohort study of 343 patients

Neuro-Oncology Advances, 2021
Background 5-Aminolevulic acid-guided surgery (5-ALA-GS) improves the extent of resection (EoR) and progression-free survival in patients with glioblastoma multiforme (GBM).
Asfand Baig Mirza, Ioannis Christodoulides, J. Lavrador, A. Giamouriadis, A. Vastani, T. Boardman, R. Ahmed, I. Norman, Christopher Murphy, Sharmila Devi, F. Vergani, R. Gullan, R. Bhangoo, K. Ashkan   +13 more
semanticscholar   +1 more source

Kinetics of 5-aminolevulinic acid-induced fluorescence in organ cultures of bronchial epithelium and tumor [PDF]

, 2002
Background: 5-Aminolevulinic acid (5-ALA)-induced protoporphyrin IX (PPIX) fluorescence improves the differentiation of tumor and normal tissue in the bladder, skin and brain. Objective: The kinetics of 5-ALA-induced protoporphyrin IX (PPIX) fluorescence
Al-Batran, Salah, Baumgartner, Reinhold, Bergner, Albrecht, Castro, Mirna, Gamarra, Fernando, Hautmann, Hubert, Huber, Rudolf M., Maier, Irmgard, Wagner, Simon   +8 more
core   +1 more source

Neuroprotective effects of 5-aminolevulinic acid against neurodegeneration in rat models of Parkinson's disease and stroke

Journal of Pharmacological Sciences, 2020
Oxidative stress is associated with the progression of the neurodegenerative diseases Parkinson's disease (PD) and cerebral ischemia. Recently, 5-aminolevulinic acid (5-ALA), an intermediate in the porphyrin synthesis pathway, was reported to exert ...
Masanori Hijioka, Kanori Kitamura, Daijiro Yanagisawa, Kaneyasu Nishimura, Kazuyuki Takata, Masatoshi Inden, Yoshihisa Kitamura   +6 more
doaj   +1 more source

Novel pathway for corrinoid compounds production in lactobacillus [PDF]

, 2018
Vitamin B12 or cobalamin is an essential metabolite for humans, which makes it an interesting compound for many research groups that focus in different producer-strains synthesis pathways.
Font, Graciela Maria, Saavedra, Maria Lucila, Taranto, Maria Pia, Torres, Andrea Carolina, Vannini, María Verónica   +4 more
core   +2 more sources

Bioquímica e ação citotóxica de alfa-aminocetonas endógenas Biochemistry and cytotoxicity of alpha-aminoketones

Química Nova, 2005
alpha-Aminoketones are expected to undergo enolization and subsequent aerobic oxidation yielding oxyradicals and highly toxic a-oxoaldehydes. Our interest has been focused on two endogenous a-aminoketones: 5-aminolevulinic acid (ALA) and aminoacetone (AA)
Fernando Dutra, Etelvino J. H. Bechara
doaj   +1 more source

5-Aminolevulinic acid: A matter of life and caveats

Journal of Photochemistry and Photobiology, 2021
Our mini-review concerns the potential adverse pro-oxidant role of 5-aminolevulinic (ALA), the first protoporphyrin IX (PP-IX)/heme precursor widely used in commercial formulations for endogenous photodynamic therapy (PDT).
Etelvino J.H. Bechara, Luiz D. Ramos, Cassius V. Stevani   +2 more
doaj   +1 more source

Efficient bioproduction of 5-aminolevulinic acid, a promising biostimulant and nutrient, from renewable bioresources by engineered Corynebacterium glutamicum

Biotechnology for Biofuels, 2020
5-Aminolevulinic acid (5-ALA) is a promising biostimulant, feed nutrient, and photodynamic drug with wide applications in modern agriculture and therapy.
Jiuzhou Chen, Yu Wang, Xuan Guo, D. Rao, Wenjuan Zhou, Ping Zheng, Jibin Sun, Yanhe Ma   +7 more
semanticscholar   +1 more source

Photodynamic Therapy of Necrobiosis Lipoidica - A Multicenter Study of 18 Patients [PDF]

, 2008
Background: Necrobiosis lipoidica (NL) is a granulomatous skin disease of unknown origin, and no reliably effective treatment option exists to handle this often disfiguring disease.
Arenberger, P., Berking, C., Hegyi, J., Jemec, G. B. E., Ruzicka, Thomas   +4 more
core   +1 more source

Fluorescence-Guided High-Grade Glioma Surgery More Than Four Hours After 5-Aminolevulinic Acid Administration

Frontiers in Neurology, 2021
Background: Fluorescence-guided surgery (FGS) using 5-aminolevulic acid (5-ALA) is a widely used strategy for delineating tumor tissue from surrounding brain intraoperatively during high-grade glioma (HGG) resection. 5-ALA reaches peak plasma levels ~4 h
G. Maragkos, Alexander J. Schüpper, N. Lakomkin, Panagiotis A. Sideras, Gabrielle A. Price, Rebecca B. Baron, T. Hamilton, Sameah Haider, I. Lee, C. Hadjipanayis, A. Robin   +10 more
semanticscholar   +1 more source