Results 31 to 40 of about 13,836,694 (159)

Evolutionary Trend Analysis of Research on 5-ALA Delivery and Theranostic Applications Based on a Scientometrics Study

Pharmaceutics, 2022
5-aminolevulinic acid (5-ALA) has been extensively studied for its sustainability and broad-spectrum applications in medical research and theranostics, as well as other areas.
You Zhou, Mulan Mo, Dexu Luo, Yi Yang, Jialin Hu, Chenqing Ye, Longxiang Lin, Chuanshan Xu, Wenjie Chen   +8 more
doaj   +1 more source

Severe hypotension and postoperative cardiac arrest caused by 5-aminolevulinic acid: a case report

Journal of Medical Case Reports
Background Although 5-aminolevulinic acid is useful for the photodynamic diagnosis of bladder tumors, it often causes severe intraoperative hypotension.
Taishi Miyazaki, Shinya Taguchi, Norihiko Obata, Satoshi Mizobuchi   +3 more
doaj   +1 more source

5-Aminolevulinic acid fermentation using engineered Saccharomyces cerevisiae

Microbial Cell Factories, 2019
Background 5′-Aminolevulinic acid (ALA) is widely used in the pharmaceutical industry, healthcare, and food production, and is a substrate for the biosynthesis of heme, which is required for respiration and photosynthesis. Enhancement of ALA biosynthesis
Kiyotaka Y. Hara, Masaru Saito, Hiroko Kato, Kana Morikawa, Hiroshi Kikukawa, Hironari Nomura, Takanori Fujimoto, Yoko Hirono-Hara, Shigeyuki Watanabe, Kengo Kanamaru, Akihiko Kondo   +10 more
doaj   +1 more source

Identification of risk factors associated with oral 5-aminolevulinic acid induced adverse events in photodynamic diagnosis−transurethral resection of bladder tumor

Photodiagnosis and Photodynamic Therapy
Background: Oral 5-aminolevulinic acid for transurethral resection of bladder tumor reduces bladder cancer recurrence compared with standard white-light transurethral resection of bladder tumor.
Yu Okabe, Yuichiro Fukuhara, Wataru Matsuoka, Nobuyuki Nakamura, Hiroshi Matsuzaki, Takeshi Miyazaki, Naotaka Gunge, Kosuke Tominaga, Kazuna Tsubouchi, Masahiro Tachibana, Chizuru Nakagawa, Fumihiro Yamazaki, Nobuhiro Haga   +12 more
doaj   +1 more source

Detection of Canine Urothelial Carcinoma Cells in Urine Using 5-Aminolevulinic Acid

Animals, 2022
This study aimed to establish a method to detect canine urothelial carcinoma cells in urine using 5-aminolevulinic acid (5-ALA) and to evaluate its diagnostic accuracy.
Kenjiro Kaji, Tomohiro Yonezawa, Yasuyuki Momoi, Shingo Maeda   +3 more
doaj   +1 more source

Selective photosensitizer localization in the human endometrium after intrauterine application of 5-aminolevulinic acid [PDF]

, 1996
OBJECTIVE:Our purpose was twofold: to determine the distribution of the endogenous photosensitizer protoporphyrin IX in the uterus and to ascertain the time interval leading to maximal endometrial fluorescence after intrauterine instillation of 5 ...
Tadir, Yona, Wyss, Pius, Krasieva, Tatiana, Lin, Fritz, DiSaia, Philip J, Fehr, Mathias K, Tromberg, Bruce J   +6 more
core   +1 more source

A case in which bladder cancer invaded the ureteral orifice and was resected via photodynamic diagnosis‐assisted transurethral resection involving orally administered 5‐aminolevulinic acid

IJU Case Reports, 2019
Introduction Transurethral resection of bladder tumor is widely used in combination with photodynamic diagnosis to treat non‐muscle invasive bladder cancer.
Keitaro Watanabe, Suguru Shirotake, Yuta Umezawa, Takayuki Takahashi, Takeshi Yamanaka, Noriaki LSanto, Takashi Okabe, Gou Kaneko, Katsuhiro Sano, Masanori Yasuda, Kent Kanao, Masafumi Oyama, Koshiro Nishimoto   +12 more
doaj   +1 more source

Comparative experimental study of 5-ALA and 5-ALA hexyl ester specific activity

Biomedical Photonics, 2018
A comparative experimental study of the specific activity of drugs based on 5-aminolevulinic acid (5-ALA) and its hexyl ester (5-ALA HE) was carried out. Their ability to induce the synthesis of photoactive protoporphyrin IX in the healthy tissues of the
R. I. Yakubovskaya, A. A. Pankratov, E. V. Filonenko, E. A. Lukyanets, V. I. Ivanova-Radkevich, A. A. Trushin, A. D. Kaprin   +6 more
doaj   +1 more source

Glioblastoma‐derived extracellular vesicle subpopulations following 5‐aminolevulinic acid treatment bear diagnostic implications

Journal of Extracellular Vesicles, 2022
Liquid biopsy is a minimally invasive alternative to surgical biopsy, encompassing different analytes including extracellular vesicles (EVs), circulating tumour cells (CTCs), circulating tumour DNA (ctDNA), proteins, and metabolites.
Tiffaney Hsia, Anudeep Yekula, S. Maheen Batool, Yulia B. Rosenfeld, Dong Gil You, Ralph Weissleder, Hakho Lee, Bob S. Carter, Leonora Balaj   +8 more
doaj   +1 more source

Pretreatment with 5-aminolevulinic acid mitigates heat stress of cucumber leaves

, 2012
Cucumber seedlings were pretreated with 3 μM 5-aminolevulinic acid (ALA) followed by cultivation at normal (25/18 °C) or high (42/38 °C) day/night temperature to investigate the protective effects of ALA on heat stress in plants.
D. -M. Li, J. Zhang, J. -G. Bai, B. Yu, C. -X. Xia, Y. Gao   +5 more
core   +1 more source