Active and Higher Intracellular Uptake of 5-Aminolevulinic Acid in Tumors may be Inhibited by Glycine [PDF]
Topical 5-aminolevulinic acid is used for the fluorescence-based diagnosis and photodynamic treatment of superficial precancerous and cancerous lesions of the skin.
Abels, Christoph +6 more
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Photodynamic therapy of Bowen’s disease
Bowen’s disease is a form of non-invasive (in situ) squamous cell skin cancer localized in the non-genital area. Russian and European clinical guidelines include photodynamic therapy (PDT) in the standard of care for patients with Bowen’s disease. In the
E. V. Filonenko, V. I. Ivanova-Radkevich
doaj +1 more source
Background/Purpose: Topical 5-aminolevulinic acid-mediated photodynamic therapy (ALA-PDT) is effective for treatment of oral precancerous and cancerous lesions. This in vitro study tried to examine whether the SCC4 cell killing by ALA-PDT was enhanced by
Yang, Deng-Fu; Lee, Jeng-Woei; Chen, Hsin-Ming; Huang, Zheng; Hsu, Yih-Chih
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Enhanced Delivery of 5‐Aminolevulinic Acid by Lecithin Invasomes in 3D Melanoma Cancer Model [PDF]
Photodynamic therapy (PDT) is a noninvasive therapeutic approach for the treatment of skin cancer and diseases. 5-Aminolevulinic acid is a prodrug clinically approved for PDT.
Alfredo Zito +12 more
core +1 more source
5-Aminolevulinic acid-mediated photodynamic therapy for oral cancers and precancers
Previous studies have used both systemic and topical 5-aminolevulinic acid (ALA)-mediated photodynamic therapy (PDT) to treat.oral precancers including oral leukoplakia (DL), oral erythroleukoplakia (DEL), and oral verrucous hyperplasia (OVH) as well as ...
Chen, Hsin-Ming;Yu, Chuan-Hang;Lin, Hung-Pin;Cheng, Shih-Jung;Chiang, Chun-Pin +1 more
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Photodynamic therapy in the treatment of onychomycosis – a review
Toenail onychomycosis is a common infection, affecting up to 14% of the population. Moreover, poor penetration of topical drugs into the nail bed leads to frequent recurrences of the disease. The cure rate of toenail onychomycosis is estimated at 63–76%.
Katarzyna Kalinowska +1 more
doaj +1 more source
Background/Purpose: Topical 5-aminolevulinic acid-mediated photodynamic therapy (ALA-PDT) is effective for treatment of human oral precancerous lesions.
Yang, Deng-Fu; Lee, Jeng-Woei; Chen, Hsin-Ming; Hsu, Yih-Chih
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Awake magic: glioblastoma resection under 5-aminolevulinic acid guidance during awake craniotomy. A case report with video demonstration [PDF]
An awake craniotomy's primary goal is to remove the tumor or damaged cells as much as possible without affecting the patient's capacity for clear thought or other crucial functions.
Aidos Moldabekov +4 more
doaj +1 more source
Photodynamic therapy in the treatment of patients with mycosis fungoides
The review highlights the current understanding of the epidemiology, etiology, pathogenesis, existing classifications of mycosis fungoides. Methods for diagnosis and treatment of the pathology are described, among which photodynamic therapy (PDT) plays ...
E. V. Filonenko, V. I. Ivanova-Radkevich
doaj +1 more source
Improvement Effect of 5-Aminolevulinic Acid on Hyperlipidemia in Miniature Schnauzer Dogs: An Open Study in 5 Cases of One Pedigree [PDF]
This is the first study to examine the long-term effect of 5-aminolevulinic acid mainly on serum lipoproteins in dogs with hyperlipidemia. We studied 5 Miniature Schnauzer cases whose fasting serum total triglyceride and very-low-density lipoprotein of ...
Sakai, Aki +7 more
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