Results 91 to 100 of about 363 (105)

Synthesis and characterization of oligonucleotides containing 5',8-cyclopurine 2'-deoxyribonucleosides: (5'R)-5',8-cyclo-2'-deoxyadenosine, (5'S)-5',8-cyclo-2'-deoxyguanosine, and (5'R)-5',8-cyclo-2'-deoxyguanosine.

Chemical Research in Toxicology, 1999
Radiation-induced degradation of purine and pyrimidine nucleosides gave rise to carbon-bridged cyclocompounds. Such cyclonucleosides represent a class of tandem lesions in which modification of both the base and 2-deoxyribose has occurred.
Anthony Romieu, D. Gasparutto, Jean Cadet   +2 more
semanticscholar   +1 more source

Effect of (5'S)-5',8-cyclo-2'-deoxyadenosine on the conformation of di and trinucleotides. A NMR and DFT study.

Organic and biomolecular chemistry, 2008
5',8-Purine cyclonucleosides constitute an important class of oxidatively generated tandem lesions whose formation involves initial hydroxyl radical-mediated hydrogen atom abstraction from the 5-hydroxymethyl group of 2-deoxyribose followed by ...
B. Karwowski, J. Gaillard, A. Grand, J. Cadet   +3 more
semanticscholar   +1 more source

Formation of 5',8-cyclo-2'-deoxyadenosine in single strand DNA. Theoretical quantum mechanics study.

Organic and biomolecular chemistry, 2010
Reactions of reactive oxygen species, and more specifically, of hydroxyl radicals, with nucleotides, may lead to the generation of radicals in the base and the 2-deoxyribose moieties of DNA.
B. Karwowski
semanticscholar   +1 more source

Solar one-way photoisomerisation of 5',8-cyclo-2'-deoxyadenosine.

Organic and biomolecular chemistry, 2008
Under sunlight irradiation (5'S)-5',8-cyclo-2'-deoxyadenosine 2 photoisomerises to the (5'R) isomer 1, which is the more easily repaired damage when these cyclopurine lesions are formed in DNA.
Liliana B. Jimenez, Susana Encinas, C. Chatgilialoglu, M. Miranda   +3 more
semanticscholar   +1 more source

(5′R)-and (5′S)-purine 5′,8-cyclo-2′-deoxyribonucleosides: reality or artifactual measurements? A reply to Chatgilialoglu’s comments (this issue)

Free radical research, 2019
This rebuttal letter is aimed at refuting the poor and false arguments elaborated by Chatgilialoglu (preceding article) in his response to the position article (Cadet et al. Free Radic Res 2019;53:574–577) that focussed on the putative reliability of the
J. Cadet, P. Di Mascio, J. Wagner
semanticscholar   +1 more source

DNA damage products (5'R)- and (5'S)-8,5'-cyclo-2'-deoxyadenosines as potential biomarkers in human urine for atherosclerosis.

Biochemistry, 2012
We hypothesized that DNA damage products (5'R)-8,5'-cyclo-2'-deoxyadenosine (R-cdA) and (5'S)-8,5'-cyclo-2'-deoxyadenosine (S-cdA) may be well-suited biomarkers of risk and diagnosis for atherosclerosis.
P. Jaruga, R. Różalski, A. Jawień, A. Migdalski, R. Oliński, M. Dizdaroglu   +5 more
semanticscholar   +1 more source

Purine 5′,8-cyclo-2′-deoxynucleoside lesions: formation by radical stress and repair in human breast epithelial cancer cells

Free radical research, 2017
M. Krokidis, Michael A. Terzidis, E. Efthimiadou, Sevasti-Kiriaki Zervou, G. Kordas, K. Papadopoulos, A. Hiskia, D. Kletsas, C. Chatgilialoglu   +8 more
semanticscholar   +1 more source

Site-Specific Introduction of (5‘S)-5‘,8-Cyclo-2‘-deoxyadenosine into Oligodeoxyribonucleotides

, 1998
A. Romieu, D. Gasparutto, D. Molko, J. Cadet   +3 more
semanticscholar   +1 more source

The role of (5′R) and (5′S) 5′,8-cyclo-2′-deoxyadenosine in ds-DNA structure: A comparative QM/MM theoretical study

, 2013
B. Karwowski
semanticscholar   +1 more source

(5′R)-5′,8-Cyclo-2′-deoxyadenosine: NMR and DFT study of its influence on TPOcdA structure

, 2008
B. Karwowski
semanticscholar   +1 more source