Results 21 to 30 of about 128,410,485 (63)

UEG Week 2014 Poster Presentations

, 2014
United European Gastroenterology Journal, Volume 2, Issue S1, Page A132-A605, October 2014.
wiley   +1 more source

Kinetic and Structural Mechanisms of (5′S)‑8,5′-Cyclo-2′-deoxyguanosine-Induced DNA Replication Stalling

, 2016
The (5′S)-8,5′-cyclo-2′-deoxyguanosine (S-cdG) lesion is produced from reactions of DNA with hydroxyl radicals generated from ionizing radiation or endogenous oxidative metabolisms.
Wenyan Xu (1453525), Adam M. Ouellette (1682827), Storm J. Shriver (1682833), Spencer M. Anderson (1682830), Zdzislaw Wawrzak (1330530), Linlin Zhao (555492)   +5 more
core   +1 more source

Oligonucleotide Incorporation and Base Pair Stability of 9-Deaza-2′-deoxyguanosine, an Analogue of 8-Oxo-2′-deoxyguanosine

, 2016
9-Deaza-2′-deoxyguanosine (CdG) is a C-nucleoside and an analogue of the abundant promutagen 8-oxo-2′-deoxyguanosine (OdG). Like 2′-deoxyguanosine (dG), CdG should form a stable base pair with dC, but similar to OdG, CdG contains an N7-hydrogen that ...
Carol A. Parish (669279), Michelle L. Hamm (2022451), Jennifer L. Carman (2274328), Anna J. Parker (2101213), Tyler W. E. Steele (2274331)   +4 more
core   +1 more source

Mutagenicity of secondary oxidation products of 8-oxo-7,8-dihydro-2'-deoxyguanosine 5'-triphosphate (8-hydroxy-2'-deoxyguanosine 5'-triphosphate) [PDF]

, 2011
8-Oxo-7,8-dihydroguanine (8-hydroxyguanine) is oxidized more easily than normal nucleobases, which can produce spiroiminodihydantoin (Sp) and guanidinohydantoin (Gh).
Hori, Mika, Suzuki, Tetsuya, Hideyoshi Harashima, Akira Matsuda, Minakawa, Noriaki, Harashima, Hideyoshi, Noriaki Minakawa, Mika Hori, Hiroyuki Kamiya, Matsuda, Akira, Kamiya, Hiroyuki, Tetsuya Suzuki   +11 more
core   +1 more source

(5′S)-8,5′-Cyclo-2′-deoxyguanosine Is a Strong Block to Replication, a Potent pol V-Dependent Mutagenic Lesion, and Is Inefficiently Repaired in Escherichia coli

, 2015
8,5′-Cyclopurines, making up an important class of ionizing radiation-induced tandem DNA damage, are repaired only by nucleotide excision repair (NER).
Ashis K. Basu (630373), Yue Zou (15851), Rajat S. Das (1277673), Benjamin A. Hilton (1277670), Savithri Weerasooriya (630371), Vijay P. Jasti (630372)   +5 more
core   +1 more source

(5′S)-8,5′-Cyclo-2′-deoxyguanosine Is a Strong Block to Replication, a Potent pol V-Dependent Mutagenic Lesion, and Is Inefficiently Repaired in Escherichia coli

, 2011
8,5′-Cyclopurines, making up an important class of ionizing radiation-induced tandem DNA damage, are repaired only by nucleotide excision repair (NER).
Vijay P. Jasti, Zou, Yue, Das, Rajat S., Hilton, Benjamin A., Savithri Weerasooriya, Yue Zou, Basu, Ashis K., Benjamin A. Hilton, Jasti, Vijay P., Rajat S. Das, Ashis K. Basu, Weerasooriya, Savithri   +11 more
core   +1 more source

Conversion of adenine and guanine bases to cyclo dA and cyclo dG bases.

, 2014
A, Formation of 2′-deoxyadenosine to (5′S) 8,5′-cyclo-2′-dA and (5′R) 8,5′-cyclo-2′-dA. B, Formation of 2′-deoxyguanosine to (5′S) 8,5′-cyclo-2′-dG and (5′R) 8,5′-cyclo-2′-dG.
Avvaru N. Suhasini (663612), Jochen Kuper (50292), Taraswi Banerjee (663613), Daniel L. Kaplan (663614), Caroline Kisker (50296), Irfan Khan (640146), Joshua A. Sommers (12889), Robert M. Brosh Jr (408931)   +7 more
core   +1 more source

Site-Specific Introduction of (5‘S)-5‘,8-Cyclo-2‘-deoxyadenosine into Oligodeoxyribonucleotides

, 2016
Site-Specific Introduction of (5‘S)-5‘,8-Cyclo-2‘-deoxyadenosine into ...
Anthony Romieu (27583), Didier Molko (3043434), Jean Cadet (14780), Didier Gasparutto (6669)   +3 more
core   +1 more source

One-Electron Oxidation of the Guanine Moiety of 2‘-Deoxyguanosine:  Influence of 8-Oxo-7,8-dihydro-2‘-deoxyguanosine

, 2016
The influence of 8-oxo-7,8-dihydro-2‘-deoxyguanosine (8-oxodGuo) on riboflavin and UVA-mediated one-electron oxidation of an aqueous aerated solution of 2‘-deoxyguanosine (dGuo) has been studied.
Christine Saint-Pierre (64135), Jean Cadet (14780), Jean-Luc Ravanat (542307)   +2 more
core   +2 more sources

An Adduct between Peroxynitrite and 2‘-Deoxyguanosine:  4,5-Dihydro-5-hydroxy-4-(nitrosooxy)-2‘-deoxyguanosine

, 2016
The reactivity of peroxynitrite (OONO-) with DNA is of interest because it is released during chronic inflammation, a major contributor to cancer. Peroxynitrite was found to undergo homolytic addition to the C4−C5 double bond of 2‘-deoxyguanosine with ...
Thierry Douki (298019), Jean Cadet (14780), Bruce N. Ames (523848)   +2 more
core   +1 more source