Results 31 to 40 of about 35,251,522 (102)

(5′S)-8,5′-Cyclo-2′-deoxyguanosine Is a Strong Block to Replication, a Potent pol V-Dependent Mutagenic Lesion, and Is Inefficiently Repaired in Escherichia coli

, 2015
8,5′-Cyclopurines, making up an important class of ionizing radiation-induced tandem DNA damage, are repaired only by nucleotide excision repair (NER).
Ashis K. Basu (630373), Yue Zou (15851), Rajat S. Das (1277673), Benjamin A. Hilton (1277670), Savithri Weerasooriya (630371), Vijay P. Jasti (630372)   +5 more
core   +1 more source

Urinary 8-Hydroxy-2'-Deoxyguanosine: A Biomarker for Radiation-Induced Oxidative DNA Damage in Pediatric Cardiac Catheterization. [PDF]

, 2017
関西医科大学博士（医学）平成29年度To determine the utility of urinary 8-hydroxy-2'-deoxyguanosine (8-OHdG) as a sensitive biomarker for radiation-induced cellular DNA damage in children undergoing cardiac catheterization.We enrolled pediatric patients with congenital ...
Kato, Shogo, Kimata, Takahisa, Uchiyama, Takamichi, カトウ, ショウゴ, Mine, Kenji, 加藤, 正吾, Kaneko, Kazunari, Yoshimura, Ken   +7 more
core  

(5′S)-8,5′-Cyclo-2′-deoxyguanosine Is a Strong Block to Replication, a Potent pol V-Dependent Mutagenic Lesion, and Is Inefficiently Repaired in Escherichia coli

, 2011
8,5′-Cyclopurines, making up an important class of ionizing radiation-induced tandem DNA damage, are repaired only by nucleotide excision repair (NER).
Vijay P. Jasti, Zou, Yue, Das, Rajat S., Hilton, Benjamin A., Savithri Weerasooriya, Yue Zou, Basu, Ashis K., Benjamin A. Hilton, Jasti, Vijay P., Rajat S. Das, Ashis K. Basu, Weerasooriya, Savithri   +11 more
core   +1 more source

Solar one-way photoisomerisation of 5',8-cyclo-2'-deoxyadenosine

, 2008
Under sunlight irradiation (5'S)-5',8-cyclo-2'-deoxyadenosine 2 photoisomerises to the (5'R) isomer 1, which is the more easily repaired damage when these cyclopurine lesions are formed in ...
Miranda Miguel A, Jimenez Liliana B, Encinas Susana, Chatgilialoglu Chryssostomos   +3 more
core   +1 more source

Conversion of adenine and guanine bases to cyclo dA and cyclo dG bases.

, 2014
A, Formation of 2′-deoxyadenosine to (5′S) 8,5′-cyclo-2′-dA and (5′R) 8,5′-cyclo-2′-dA. B, Formation of 2′-deoxyguanosine to (5′S) 8,5′-cyclo-2′-dG and (5′R) 8,5′-cyclo-2′-dG.
Avvaru N. Suhasini (663612), Jochen Kuper (50292), Taraswi Banerjee (663613), Daniel L. Kaplan (663614), Caroline Kisker (50296), Irfan Khan (640146), Joshua A. Sommers (12889), Robert M. Brosh Jr (408931)   +7 more
core   +1 more source

Advances in Nucleic Acid Research: Exploring the Potential of Oligonucleotides for Therapeutic Applications and Biological Studies. [PDF]

Int J Mol Sci, 2023
Moccia M, Pascucci B, Saviano M, Cerasa MT, Terzidis MA, Chatgilialoglu C, Masi A.   +6 more
europepmc   +1 more source

Chemical structures of 8-hydroxy-2′-deoxyguanosine (8-oxodG), 5-hydroxymethyluracil (5-HMUra) and cimetidine (used as internal standard - IS).

, 2013
Chemical structures of 8-hydroxy-2′-deoxyguanosine (8-oxodG), 5-hydroxymethyluracil (5-HMUra) and cimetidine (used as internal standard - IS).
Pedro Silva (219069), Fernando Aveiro (385795), José S. Câmara (385797), Jorge Pereira (385796), Berta Mendes (385794)   +4 more
core   +1 more source

Competitive Multiple-Mechanism-Driven Electrochemiluminescent Detection of 8‑Hydroxy-2′-deoxyguanosine

, 2018
Natural selection over billions of years has developed highly effective in vivo signal transduction that is often governed by a series of competitive multiple mechanisms.
Shiyu Chen (1545418), Songqin Liu (1455040), Yuanjian Zhang (1437160), Qing Zhou (52712), Yanfei Shen (1455043), Yanqin Lv (2803120), Jingjing Ji (1597363)   +6 more
core   +1 more source

Fluorine-containing nucleosides for 19F NMR-based structural studies of nucleic acids: synthesis and characterization of 8-CF3-2’-deoxyguanosine

, 2012
Aiming at the preparation of 19F-labelled monomers, allowing to exploit 19F nuclei as probes for NMR studies on nucleic acids, and particularly G-quadruples structures, we focused our attention on the unprecedented 8-CF3 analog of 2’-deoxyguanosine.
MUSUMECI, DOMENICA, MONTESARCHIO, DANIELA   +1 more
core  

Assessing the Formation of Purine Lesions in Mitochondrial DNA of Cockayne Syndrome Cells. [PDF]

Biomolecules, 2022
Chatgilialoglu C, Krokidis MG, Masi A, Barata-Vallejo S, Ferreri C, Pascucci B, D'Errico M.   +6 more
europepmc   +1 more source