Results 31 to 39 of about 54 (39)
, 2011 8,5’-Cyclopurine-2’-deoxynucleosides are unique tandem DNA lesions formed by oxidation or ionizing radiation, which are repaired only by nucleotide excision repair. They have been suspected to be responsible for neurodegeneration and other diseases.
Ashis K. Basu +3 more
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Exposure of aqueous solutions of DNA to X- or γ-rays, which induces the hydroxyl radical as one of the major reactive oxygen species (ROS), can result in the generation of a battery of single-nucleobase and bulky DNA lesions. These include the (5′R) and (
Candace R. Guerrero (1331547) +2 more
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Stability of N‑Glycosidic Bond of (5′S)‑8,5′-Cyclo-2′-deoxyguanosine
8,5′-Cyclopurine deoxynucleosides are unique tandem lesions containing an additional covalent bond between the base and the sugar. These mutagenic and genotoxic lesions are repaired only by nucleotide excision repair. The N-glycosidic (or C1′-N9) bond of
Ashis K. Basu (630373) +4 more
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Misguided Panic and Missed Opportunity for Pharmaceutical Inventions: How Unexpected Results Eclipsed Reasonable Expectation of Success in BMS v. Teva [PDF]
, 2019 Pride, Christelle K.
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, 2016 Οι πλούσιες σε γουανίνη (G) αλληλουχίες του DNA και RNA μπορούν αυθόρμητα να αυτοργανωθούν σε υπερμοριακές ελικοειδείς δομές τετραμερών δομών της γουανίνης με ιόντα μετάλλων (G-quadruplexes), οι οποίες αντιπροσωπεύουν ελκυστικούς στόχους για το ...
Γαγλία Λαμπρινή
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Synthese carbocyclischer Analoga oxidativ erzeugter DNA-Schäden [PDF]
, 2008 Mueller, Heiko Carl
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Untersuchungen zum Replikationsverhalten carbozyklischer Analoga der Formamidopyrimidine des 2´-Desoxyadenosin und 2´-Desoxyguanosin [PDF]
, 2012 Gehrke, Tim
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