Results 11 to 20 of about 35,251,522 (102)
Induction of 8,5′-Cyclo-2′-deoxyadenosine and 8,5′-Cyclo-2′-deoxyguanosine in Isolated DNA by Fenton-Type Reagents [PDF]
Chemical Research in Toxicology, 2013 Yinsheng Wang, Jin Wang
exaly +2 more sources
Oxidative stress and 8-oxoguanine repair are enhanced in colon adenoma and carcinoma patients. [PDF]
, 2010 Oxidative stress is involved in the pathogenesis of colon cancer. We wanted to elucidate at which stage of the disease this phenomenon occurs. In the examined groups of patients with colorectal cancer (CRC, n = 89), benign adenoma (AD, n = 77) and ...
R. Rozalski +31 more
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Synthesis of [1,3, NH2‐15N3] (5′S)‐8,5′‐cyclo‐2′‐deoxyguanosine [PDF]
Journal of Labelled Compounds and Radiopharmaceuticals, 2013 Ashis Basu, Rajat Das
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Chemistry and Biology of 8,5\u27-Cyclo-2\u27-deoxyguanosine and Other DNA Lesions
, 2013 8,5’-Cyclopurine deoxynucleosides are unique tandem lesions containing an additional covalent bond between the base and the sugar. These mutagenic and genotoxic lesions are repaired only by nucleotide excision repair (NER). It was shown that the R-cdA is
Das, Rajat S
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Stability of N‑Glycosidic Bond of (5′S)‑8,5′-Cyclo-2′-deoxyguanosine
, 2016 8,5′-Cyclopurine deoxynucleosides are unique tandem lesions containing an additional covalent bond between the base and the sugar. These mutagenic and genotoxic lesions are repaired only by nucleotide excision repair. The N-glycosidic (or C1′-N9) bond of
Ashis K. Basu (630373) +4 more
core +1 more source
, 2016 Exposure of aqueous solutions of DNA to X- or γ-rays, which induces the hydroxyl radical as one of the major reactive oxygen species (ROS), can result in the generation of a battery of single-nucleobase and bulky DNA lesions. These include the (5′R) and (
Candace R. Guerrero (1331547) +2 more
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8-Fluoro-N-2-isobutyryl-2′-deoxyguanosine: Synthesis and Reactivity
, 2020 3′,5′-O-Bis(tert-butyldimethylsilyl)-8-fluoro-N-2-isobutyryl-2′-deoxyguanosine was synthesized from 3′,5′-O-bis(tert-butyldimethylsilyl)-N-2-isobutyryl-2′-deoxyguanosine by the treatment with N-fluorobenzenesulfonimide.
Andrei Solodinin +3 more
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Imidazopurinones are markers of physiological genomic damage linked to DNA instability and glyoxalase 1-associated tumour multidrug resistance [PDF]
, 2010 Glyoxal and methylglyoxal are reactive dicarbonyl metabolites formed and metabolized in physiological systems. Increased exposure to these dicarbonyls is linked to mutagenesis and cytotoxicity and enhanced dicarbonyl metabolism by overexpression of ...
Rabbani, Naila +7 more
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, 2016 The influence of 8-oxo-7,8-dihydro-2‘-deoxyguanosine (8-oxodGuo) on riboflavin and UVA-mediated one-electron oxidation of an aqueous aerated solution of 2‘-deoxyguanosine (dGuo) has been studied.
Christine Saint-Pierre (64135) +2 more
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Structures of (5′S)-8,5′-Cyclo-2′-deoxyguanosine Mismatched with dA or dT
, 2015 Diastereomeric 8,5′-cyclopurine 2′-deoxynucleosides, containing a covalent bond between the deoxyribose and the purine base, are induced in DNA by ionizing radiation.
Ashis K. Basu (630373) +3 more
core +1 more source