Results 251 to 260 of about 12,326,283 (294)
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5-ALA based photodynamic management of glioblastoma
SPIE Proceedings, 2014Objective: Improvement of the clinical outcome of glioblastoma (GBM) patients by employment of fluorescence and photosensitization on the basis of 5-aminolevulinic acid (5-ALA) induced protoporphyrin IX (PpIX). Methods: In this report the focus is laid on the use of tumor selective PpIX fluorescence for stereotactic biopsy sampling and intra ...
Adrian Rühm +8 more
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Does 5-ALA have a radiosensitizing effect?
2014Objective: Emitting red light and the generation of reactive oxygen species are two physical reactions of protoporphyrin IX (PPIX) upon irradiation with different wavelength of light. These two mechanisms are widely used either as an intraoperative tumor marker or to directly “attack” [for full text, please go to the a.m. URL]
Nemes, A +4 more
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The immunogenic effect of 5-ALA-Photodynamic Therapy
2010Objective: 5-Aminolevulinic acid-mediated photodynamic therapy (ALA/PDT) can improve clinical outcome in patients suffering from glioblastoma multiforme (GBM). Due to the limited penetration of the laser light into brain tissue, however, additional mechanisms besides direct phototoxicity have to[for full text, please go to the a.m. URL]
Etminan, N +4 more
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2012
Objective: 5-aminolaevulinic acid (5-ALA) has improved surgical therapy of malignant gliomas. However, there is a lack of knowledge concerning 5-ALA uptake and fluorescence kinetic in different histologies. Aim of this study was to detect differences in malignant gliomas concerning uptake kinetic and[for full text, please go to the a.m. URL]
Schroeteler, J +5 more
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Objective: 5-aminolaevulinic acid (5-ALA) has improved surgical therapy of malignant gliomas. However, there is a lack of knowledge concerning 5-ALA uptake and fluorescence kinetic in different histologies. Aim of this study was to detect differences in malignant gliomas concerning uptake kinetic and[for full text, please go to the a.m. URL]
Schroeteler, J +5 more
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5-ALA-induced fluorescence in cerebral metastases
201667. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), 1. Joint Meeting mit der Koreanischen Gesellschaft für Neurochirurgie (KNS)
Kamp, MA, Rapp, M, Steiger, HJ, Sabel, M
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5-ALA-PDT induces RIP3-dependent necrosis in glioblastoma
Photochemical & Photobiological Sciences, 2011Glioblastoma constitute the most frequent and deadliest brain tumors of astrocytic origin. They are resistant to all current therapies and are associated with a high rate of recurrence. Glioblastoma were previously shown to respond to treatments by 5-aminolevulinic acid (5-ALA)-based photodynamic therapy (PDT) mainly by activating a necrotic type of ...
Coupienne, Isabelle +4 more
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Intraoperative 5-ALA induzierte Fluoreszenzoptische Nebenschilddrüsendetektion
2002Zielsetzung: 5-Aminolavulinsaure (5-ALA) kann in verschiedenen Geweben eine intrazellulare ProtoporphyrinIX (PpIX) Akkumulation induzieren. PpIX ist mit Licht einer bestimmten Wellenlange (blau) zur Fluoreszenz (rot) anregbar. Experimentell reichert die Nebenschilddruse (NSD) PpIX nach systemischer 5-ALA Applikation an.
J. Gahlen +3 more
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European journal of clinical pharmacology, 2000
In an open study, the local and systemic side effects and pharmacokinetics of 5-aminolevulinic acid (5-ALA) and the fluorescent metabolite protoporphyrin IX (PPIX) were investigated after intravesical administration for the fluorescent photodetection of superficial bladder carcinoma.In 20 patients with confirmed bladder carcinoma, 5-ALA was introduced ...
G, Popken +4 more
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In an open study, the local and systemic side effects and pharmacokinetics of 5-aminolevulinic acid (5-ALA) and the fluorescent metabolite protoporphyrin IX (PPIX) were investigated after intravesical administration for the fluorescent photodetection of superficial bladder carcinoma.In 20 patients with confirmed bladder carcinoma, 5-ALA was introduced ...
G, Popken +4 more
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5-ALA derivative-mediated photoinactivation of Propionibacterium acnes
Journal of Dermatological Science, 2009Nicolas, Fotinos +6 more
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Neuronavigatie en 5-ALA-fluorescentie
Tijdschrift voor Geneeskunde, 2014HALLAERT G, CAEMAERT J
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