Absence of Interaction Between 5α-Reductase Inhibitors and Glucocorticoids on Incidence of Myocardial Infarction in People With Type 2 Diabetes. [PDF]
Tu H +7 more
europepmc +1 more source
Curcumin versus placebo in benign prostatic hyperplasia: a systematic review and meta-analysis. [PDF]
Santana DS +9 more
europepmc +1 more source
Ammonia fumigation combined with nitrogen inhibitor reduces root-knot nematode populations and N<sub>2</sub>O emission but not bacterial alpha diversity. [PDF]
Shi F, Fu J, Li P, Li X, Liu J, Zhu Y.
europepmc +1 more source
Targeting Aromatase and 5-α-Reductase to Limit Dysfunctional Adipogenesis in Multiple Symmetric Lipomatosis. [PDF]
Milan G +15 more
europepmc +1 more source
Androgen-Modulating Drugs and Severe Complications After ST-Elevation Myocardial Infarction.
Colldén H +5 more
europepmc +1 more source
5-Alpha-Reductase Inhibitors and Combination Therapy
By inhibiting the conversion from testosterone to dihydrotestosterone 5-Alpha reductase inhibitors (5ARIs) are able to hinder prostatic growth, shrink prostate volumes, and improve BPH-related LUTS. 5ARIs are particularly beneficial for patients with larger prostates (>30-40ml).
Marc Philipp Schneider +1 more
exaly +5 more sources
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The risk of dementia with the use of 5 alpha reductase inhibitors
Journal of the Neurological Sciences, 2017There has been considerable interest in the interplay between testosterone and cognition. Dihydrotestosterone (DHT), which has been correlated with cognitive function, is significantly reduced with the use of 5 alpha reductase inhibitors (5ARI) for prostatic enlargement.
Blayne Welk +2 more
exaly +3 more sources
Discovery of Natural Steroid 5 Alpha-Reductase Inhibitors
Assay and Drug Development Technologies, 2019Human steroid 5 alpha-reductases (S5αRs) and NADPH irreversibly reduce testosterone to the more potent dihydrotestosterone (DHT). S5αR inhibitors are useful treatments for DHT-dependent diseases, including benign prostatic hyperplasia, androgenic alopecia and hair growth, and acne.
C Norman Scholfield +2 more
exaly +3 more sources
5 Alpha-reductase inhibitors: whatʼs new?
Current Opinion in Urology, 2003Medical therapy is now the first-line treatment for most men with symptomatic benign prostatic hyperplasia. This review aims to highlight the recent contributions to our understanding of 5 alpha-reductase inhibitor usage.For the last decade, finasteride has been the only available 5 alpha-reductase inhibitor, acting upon the type 2 isoenzyme of 5-alpha
Charlotte L, Foley, Roger S, Kirby
openaire +2 more sources

