5-alpha reductase inhibitors - Open Access .click

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Influence of 5-Alpha Reductase Inhibitors on Prostate Cancer Detection with Magnetic Resonance Imaging: A Matched Cohort Study

Journal of Urology, 2021
Andrei S Purysko
exaly

Pharmacodynamic modeling of finasteride, a 5 alpha-reductase inhibitor.

Pharmacotherapy, 1995
Finasteride is a 4-azasteroid inhibitor of one isoenzyme of 5 alpha-reductases that converts testosterone to dihydrotestosterone (DHT). We characterized the time course of DHT concentrations. The following model was used to assess DHT pharmacodynamics: [formula: see text] where joint fitting of three dose levels yielded kin0 = 28% change/hour, kout = 0.
H C, Ko, W J, Jusko
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Treatment of hirsutism with 5 alpha-reductase inhibitors.

Clinics in endocrinology and metabolism, 1986
Much os the evidence gathered from studies of 5 alpha-reductase activity levels and androgen metabolism in the skin of hirsute women and the excretion of androgen metabolites by hirsute women indicates that 5 alpha-reduced androgens are probably of primary importance in hirsutism.
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5 Alpha-Reductase Inhibitor

2020
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5‐Alpha reductase inhibitors in androgenetic alopecia: Shifting paradigms, current concepts, comparative efficacy, and safety

Dermatologic Therapy, 2020
Aseem Sharma +2 more
exaly

5 alpha-Reductase inhibitors.

Advances in protein chemistry, 2001
J D, McConnell, E, Stoner
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5-alpha reductase inhibitors and PSA screening for prostate cancer