Results 181 to 190 of about 30,571 (234)

Emodin combined with 5-aminolevulinic acid photodynamic therapy inhibits condyloma acuminate angiogenesis by targeting SerRS. [PDF]

J Cell Mol Med
Lu H, Peng Z, Luo Y, Zheng Z, Li C, Wang Q, Han C, Wang Y, Liang L, Zeng K, Chen Y.   +10 more
europepmc   +1 more source

5-Aminolevulinic acid dehydratase from propionic acid bacteria.

Acta biochimica Polonica, 1998
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5-Aminolevulinic Acid Imaging of Malignant Glioma

Surgical Oncology Clinics of North America, 2022
High-grade glioma is the most common malignant primary brain tumor in adults. Glioma infiltration renders it difficult to treat and likely to recur. Increasing the extent of resection has been associated with improving progression-free survival and overall survival by several months. The introduction of 5-aminolevulinic acid (5-ALA) fluorescence-guided
Guan, Li, Adrian, Rodrigues, Lily, Kim, Cesar, Garcia, Shruti, Jain, Michael, Zhang, Melanie, Hayden-Gephart   +6 more
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Hemodynamic effects of 5-aminolevulinic acid in humans

Journal of Photochemistry and Photobiology B: Biology, 1998
Endogenous protoporphyrin IX (PpIX), which results from the oral administration of 5-aminolevulinic acid (ALA), is being investigated for its efficacy as a photosensitizing agent for photodynamic therapy (PDT). Clinical use of ALA has been associated with only mild gastrointestinal side effects.
M A, Herman, J, Webber, D, Fromm, D, Kessel   +3 more
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Oxidative damage to ferritin by 5-aminolevulinic acid

Archives of Biochemistry and Biophysics, 2003
5-Aminolevulinic acid (ALA), a heme precursor overproduced in various porphyric disorders, has been implicated in iron-mediated oxidative damage to biomolecules and cell structures. From previous observations of ferritin iron release by ALA, we investigated the ability of ALA to cause oxidative damage to ferritin apoprotein.
Maria E.M Rocha, Fernando Dutra, Brian Bandy, Regina L Baldini, Suely L Gomes, Adelaide Faljoni-Alário, Cleber W Liria, M Terêsa, M Miranda, Etelvino J.H Bechara   +9 more
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Fluorometric measurement of 5-aminolevulinic acid in serum

Clinica Chimica Acta, 2004
Measurement of 5-aminolevulinic acid (ALA) in serum is potentially useful in acute porphyrias, lead poisoning and hereditary tyrosinemia. Because levels of ALA in serum are about 100 times less than in urine, a highly sensitive method is required. We describe a simple and sensitive fluorometric method that does not require HPLC.ALA is separated from ...
Chul, Lee, Xian, Qiao, Douglas E, Goeger, Karl E, Anderson   +3 more
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Biosynthesis of 5-Aminolevulinic Acid

2009
5-Aminolevulinic acid (ALA) is the general precursor of all known tetrapyrroles. Currently, two different biosynthetic routes for ALA formation are known. Humans, animals, fungi and the α-group of the proteobacteria employ the one-step-condensation of succinyl-coenzyme A and glycine catalyzed by pyridoxal 5′-phosphate-dependent ALA synthase. In plants,
Dieter Jahn, Dirk W. Heinz
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5-Aminolevulinic acid synthase: mechanism, mutations and medicine

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2003
5-Aminolevulinic acid synthase (ALAS), the first enzyme of the heme biosynthesis pathway, catalyses the pyridoxal 5'-phosphate-dependent condensation between glycine and succinyl-CoA to yield 5-aminolevulinic acid (5-amino-4-oxopentanoate). A three-dimensional structural model of Rhodobacter spheroides ALAS has been constructed and used to identify ...
Shoolingin-Jordan, P.M., Al-Daihan, S., Alexeev, D., Baxter, R.L., Bottomley, S.S., Kahari, I.D., Roy, I., Sarwar, M., Sawyer, L., Wang, S.F.   +9 more
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Microbial production and applications of 5-aminolevulinic acid

Applied Microbiology and Biotechnology, 2014
5-Aminolevulinic acid (ALA), an important intermediate in tetrapyrrole biosynthesis in organisms, has been widely applied in many fields, such as medicine, agriculture, and the food industry, due to its biochemical characteristics. Research efforts supporting the microbial production of ALA have received increasing interest due to its dominant ...
Shuli, Liu, Guangming, Zhang, Xiangkun, Li, Jie, Zhang   +3 more
openaire   +2 more sources