5-Aminolevulinic acid activates the MdWRKY71-MdMADS1 module to enhance anthocyanin biosynthesis in apple. [PDF]
Zhang L, Tao H, Zhang J, An Y, Wang L.
europepmc +1 more source
Comparing Utility of Intraoperative Magnetic Resonance Imaging and 5-Aminolevulinic Acid in High-Grade Glioma Resection Surgery: A Systematic Review and Meta-Analysis. [PDF]
de Los Reyes-Nabhan NK +2 more
europepmc +1 more source
Paradoxical fluorescence after administration of 5-aminolevulinic acid for resection of a cerebral melanoma metastasis [PDF]
Beck, Jürgen +3 more
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Analysis of the Transcriptome Provides Insights into the Photosynthate of Maize Response to Salt Stress by 5-Aminolevulinic Acid. [PDF]
Jiang Y +9 more
europepmc +1 more source
Fluorescence-Guided Surgery Using 5-Aminolevulinic Acid/Protoporphyrin IX in Brain Metastases. [PDF]
Price A +9 more
europepmc +1 more source
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5-Aminolevulinic acid synthase: mechanism, mutations and medicine
Biochimica Et Biophysica Acta - Proteins and Proteomics, 20035-Aminolevulinic acid synthase (ALAS), the first enzyme of the heme biosynthesis pathway, catalyses the pyridoxal 5'-phosphate-dependent condensation between glycine and succinyl-CoA to yield 5-aminolevulinic acid (5-amino-4-oxopentanoate). A three-dimensional structural model of Rhodobacter spheroides ALAS has been constructed and used to identify ...
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5-Aminolevulinic Acid Imaging of Malignant Glioma
Surgical Oncology Clinics of North America, 2022High-grade glioma is the most common malignant primary brain tumor in adults. Glioma infiltration renders it difficult to treat and likely to recur. Increasing the extent of resection has been associated with improving progression-free survival and overall survival by several months. The introduction of 5-aminolevulinic acid (5-ALA) fluorescence-guided
Guan, Li +6 more
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The stability of 5-aminolevulinic acid in solution
Journal of Photochemistry and Photobiology B: Biology, 20025-Aminolevulinic acid (ALA) is being assessed for photodynamic therapy of cancer and other diseases worldwide. However, its stability properties in solution are not well understood yet. The breakdown of ALA in pH-buffered solutions was examined in this work.
Øystein Bech, Gadmar +4 more
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5-aminolevulinic acid (5-ALA) and its ester derivatives are used in photodynamic therapy as precursors for the formation of photosensitizers. This study relates to the mechanisms by which 5-ALA is transported into cells. The transport of 5-ALA has been studied in a human adenocarcinoma cell line (WiDr) by means of [14C]-labeled 5-ALA.
E, Rud, O, Gederaas, A, Høgset, K, Berg
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