Results 111 to 120 of about 14,205,288 (205)

Novel Bioconjugates of Aminolevulinic Acid with Nucleosides

open access: yes, 2008
Esters and amino acid derivatives of 5-aminolevulinic acid (ALA) are efficient prodrugs for the production of protoporphyrin IX (PpIX), which has been used in photodynamic cancer therapy (PDT).
Schmitt, F.   +11 more
core   +1 more source

5-Aminolevulinic Acid Drives Coordinated Astaxanthin and Lipid Accumulation in Green Alga Chromochloris zofingiensis

open access: yesFoods
Chromochloris zofingiensis, a photosynthetic microalga, has attracted considerable attention due to its ability to simultaneously accumulate lipids and astaxanthin.
Jinrui Gao   +4 more
doaj   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio
Although 5‐aminolevulinic acid (5‐ALA) has shown potential for hair growth in previous studies, the molecular mechanisms remain unclear. In this study, we investigated the combined effect of 5‐ALA with ferric ammonium citrate (FAC) in human hair follicle
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
doaj   +1 more source

5‐ALA/SFC enhances HO‐1 expression through the MAPK/Nrf2 antioxidant pathway and attenuates murine tubular epithelial cell apoptosis

open access: yesFEBS Open Bio, 2019
Cyclosporin A (CsA) is a common immunosuppressant, but its use is limited as it can cause chronic kidney injury. Oxidative stress and apoptosis play a key role in CsA‐induced nephrotoxicity.
Chi Liu   +9 more
doaj   +1 more source

Sensitivity of osteoblasts, fibroblasts, bone marrow cells, and dendritic cells to 5-aminolevulinic acid based photodynamic therapy

open access: yes, 2007
INTRODUCTION: Photodynamic therapy with 5-aminolevulinic acid (5-ALA-PDT) exerts cell type specific effects on target cells. Since chondrocytes were found to be more resistant than osteoblasts to 5-ALA-PDT, the pre-treatment of osteochondral grafts with ...
Schober, Martin   +11 more
core   +1 more source

Synergistic effects of 5-aminolevulinic acid based photodynamic therapy and celecoxib via oxidative stress in human cholangiocarcinoma cells

open access: yes, 2013
Cy Hyun Kim,1,2,* Chung-Wook Chung,1,* Hye Myeong Lee,1 Do Hyung Kim,1,2 Tae Won Kwak,1 Young-IL Jeong,1 Dae Hwan Kang1,21National Research and Development Center for Hepatobiliary Cancer, Research Institute for Convergence of Biomedical Science and ...
Chung CW   +6 more
core  

5-ALA/SFC Mitigates Tau Toxicity via Lowering Oxidative Stress in a Drosophila Model of Tau Toxicity

open access: yesLife
Mitochondrial dysfunctions contribute to the pathogenesis of tauopathies, a group of neurodegenerative diseases with abnormal accumulation of microtubule-associated protein tau. The combination of 5-aminolevulinic acid (5-ALA) and sodium ferrous citrate (
Arisa Tamura   +4 more
doaj   +1 more source

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