5-Aminolevulinic acid-mediated sonosensitization of rat RG2 glioma cells in vitro
Sonodynamic therapy (SDT) is a promising technique based on the ability of certain substances, called sonosensitizers, to sensitize cancer cells to non-thermal effects of low-energy ultrasound waves, allowing their destruction.
Krzysztof Bilmin +4 more
core +1 more source
The effects of the heme precursor 5-aminolevulinic acid (ALA) on REV-ERBα activation [PDF]
The nuclear receptor, REV-ERBα, has a key role in circadian rhythms and requires heme as its ligand. The present study determined whether the heme precursor, 5-aminolevulinic acid (ALA), affects REV-ERBα and its target genes.
Kohei Yamashita +11 more
core +1 more source
Cost-effectiveness of 5-aminolevulinic acid-induced fluorescence in malignant glioma surgery
Objective: This study evaluates the cost-effectiveness of 5-aminolevulinic acid (5-ALA, Gliolan®) in patients undergoing surgery for malignant glioma, in standard clinical practice conditions in Spain. Material and methods: Cost-effectiveness ratios were
J. Slof, R. Díez Valle, J. Galván
doaj +1 more source
Molecular Mechanisms and Regulation of Anthocyanin Biosynthesis in Rosaceae Fruits: A Review
Five‐tiered regulatory network governing anthocyanin biosynthesis in Rosaceae fruits, integrating environmental signals, epigenetic/transcriptional control, flavonoid metabolism, pigment trafficking and breeding translation. This review elaborates layered regulatory networks underlying anthocyanin production in core Rosaceae crops (Malus, Pyrus ...
Menghua Luo +3 more
wiley +1 more source
Improvement Effect of 5-Aminolevulinic Acid on Hyperlipidemia in Miniature Schnauzer Dogs: An Open Study in 5 Cases of One Pedigree [PDF]
This is the first study to examine the long-term effect of 5-aminolevulinic acid mainly on serum lipoproteins in dogs with hyperlipidemia. We studied 5 Miniature Schnauzer cases whose fasting serum total triglyceride and very-low-density lipoprotein of ...
Sakai, Aki +7 more
core +1 more source
Table1_Natural 5-Aminolevulinic Acid: Sources, Biosynthesis, Detection and Applications.docx
5-Aminolevulinic acid (5-ALA) is the key precursor for the biosynthesis of tetrapyrrole compounds, with wide applications in medicine, agriculture and other burgeoning fields. Because of its potential applications and disadvantages of chemical synthesis,
Yufeng Mao (3457196) +5 more
core +1 more source
Resumen: Objetivo: Evaluar el coste-efectividad del ácido 5-aminolevulínico (5-ALA, Gliolan®) en pacientes intervenidos quirúrgicamente de glioma maligno, en condiciones de práctica médica habitual en España.
J. Slof, R. Díez Valle, J. Galván
doaj +1 more source
Stabilization of 5-aminolevulinic acid by the zinc(II) ion in an aqueous solution [PDF]
It is known that 5-aminolevulinic acid (5-ALA) is not stable in an aqueous solution because of the auto-condensation reaction between two 5-ALA molecules; however, in this study, 5-ALA was stabilized by the zinc(II) ion in an aqueous solution of neutral ...
Tachiya, Naohisa +11 more
core +1 more source
5-Aminolevulinic acid (5-ALA) is a valuable precursor for pharmaceuticals and agriculture, but its microbial production is limited by tight coupling to essential heme biosynthesis.
Hongyan Zhang +6 more
doaj +1 more source
Effects of 5-aminolevulinic acid-mediated sonodynamic therapy on macrophages
Jiali Cheng,1,* Xin Sun,1,2,* Shuyuan Guo,1,* Wei Cao,1 Haibo Chen,1 Yinghua Jin,1 Bo Li,1 Qiannan Li,1 Huan Wang,1 Zhu Wang,3 Qi Zhou,3 Peng Wang,3 Zhiguo Zhang,3 Wenwu Cao,3,4 Ye Tian1,21Division of Cardiology, the First Affiliated Hospital ...
Zhou Q +13 more
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