Results 71 to 80 of about 14,205,288 (205)

Alleviation of Lead Stress on Sage Plant by 5-Aminolevulinic Acid (ALA)

Plants, 2021
Oxidative stress is imparted by a varying range of environmental factors involving heavy metal stress. Thus, the mechanisms of antioxidant resistance may advance a policy to improve metal tolerance.
Hamed M. El-Shora, Gehan F. Massoud, Ghada A. El-Sherbeny, Salma Saleh Alrdahe, Doaa B. Darwish   +4 more
doaj   +1 more source

The effect of photodynamic therapy in head and neck cancer: A comprehensive review of in vivo models

Photochemistry and Photobiology, EarlyView.
This review evaluates Photodynamic Therapy (PDT) in in vivo head and neck cancer models. PDT effectively generates ROS, reducing tumor growth, cell proliferation and angiogenesis while enhancing survival and immune responses. However, methodological heterogeneity highlights the urgent need for standardized dosimetric protocols to ensure reproducibility
Bibiana Padilha de Menezes da Silva, Rebeca Barros Nascimento, Giovanna Lopes Carvalho, Rebeca Boltes Cecatto, Maria Stella Moreira, Maria Fernanda Setúbal Destro Rodrigues   +5 more
wiley   +1 more source

X-ray structure of a putative reaction intermediate of 5-aminolaevulinic acid dehydratase

, 2003
The X-ray structure of yeast 5-aminolaevulinic acid dehydratase, in which the catalytic site of the enzyme is complexed with a putative cyclic intermediate composed of both substrate moieties, has been solved at 0.16 nm (1.6 Å) resolution.
Youell, J.H., Butler, D., Cooper, J.B., Erskine, P.T., Warren, M.J., Brindley, A.A., Shoolingin-Jordan, P.M., Wood, S.P., Coates, L.   +8 more
core   +1 more source

Engineering a probiotic strain of Escherichia coli to induce the regression of colorectal cancer through production of 5‐aminolevulinic acid

Microbial Biotechnology, 2021
Summary Bacterial vectors can be engineered to generate microscopic living therapeutics to produce and deliver anticancer agents. Escherichia coli Nissle 1917 (Nissle 1917) is a promising candidate with probiotic properties.
Junhao Chen, Xiaohong Li, Yumei Liu, Tianyuan Su, Changsen Lin, Lijun Shao, Lanhua Li, Wanwei Li, Guoyu Niu, Jing Yu, Ling Liu, Miaomiao Li, Xiaoli Yu, Qian Wang   +13 more
doaj   +1 more source

A low‐cost handheld device for monitoring cutaneous photosensitivity

Photochemistry and Photobiology, EarlyView.
The cutaneous photosensitivity detection (CPD) device is a handheld contact‐based measurement device using 405 nm excitation and red fluorescence detection for monitoring skin phototoxicity risk after photodynamic therapy (PDT) procedures involving systemic aminolaevulinic acid (ALA) induced protoporphyrin IX (PpIX) photosensitization.
Md Asaduzzaman Rasel, Ryan Beland, Shakir Khan, Tayyaba Hasan, Jonathan P. Celli   +4 more
wiley   +1 more source

5-Aminolevulinic acid antiviral efficacy against SARS-CoV-2 omicron variant in vitro

Tropical Medicine and Health, 2022
The coronavirus disease 2019 (COVID 19) pandemic continues to pose a threat to global health. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant (B.1.1.529) has spread rapidly worldwide and became dominant in many countries.
Mya Myat Ngwe Tun, Takaya Sakura, Yasuteru Sakurai, Yohei Kurosaki, Daniel Ken Inaoka, Norifumi Shioda, Chris Smith, Jiro Yasuda, Kouichi Morita, Kiyoshi Kita   +9 more
doaj   +1 more source

Time‐series multi‐omics analysis of micronutrient stress in Sorghum bicolor reveals iron and zinc crosstalk and regulatory network conservation

Plant Biology, EarlyView.
Overlap between Fe and Zn responsive gene regulatory networks (GRNs) were found, indicative of micronutrient crosstalk, and conservation of root and leaf GRNs and genes suggests strong constraint on homeostasis networks in plants. Abstract Micronutrient stress impacts growth, biomass production, and grain yield in crops.
A. Mishra, A. Bhat, S. Kumari, R. Sharma, J. Braynen, D. Tadesse, S. El Alaoui, S. Seaver, N. Grosjean, D. Ware, M. Xie, T. Paape   +11 more
wiley   +1 more source

Poly(L-histidine)-tagged 5-aminolevulinic acid prodrugs: new photosensitizing precursors of protoporphyrin IX for photodynamic colon cancer therapy

, 2012
Renjith P Johnson,1* Chung-Wook Chung,2* Young-Il Jeong,2 Dae Hwan Kang,2 Hongsuk Suh,3 Il Kim,11WCU Centre for Synthetic Polymer Bioconjugate Hybrid Materials, Department of Polymer Science and Engineering, Pusan National University, Pusan, 2National ...
Chung CW, Jeong YI, Renjith P. Johnson, Dae Hwan Kang, Kang DH, Chung-Wook Chung, Young-IL Jeong, Suh H, Kim I, Johnson RP, Hongsuk Suh, Kim   +11 more
core   +1 more source

5-Aminolevulinic Acid Phosphate as an Immune System Enhancer Along with Vaccination Against SARS-CoV-2 Virus Infection: An Open-Label, Randomized Pilot Study

Life
Previous studies have shown that 5-aminolevulinic acid phosphate together with sodium ferrous citrate, which is marketed as a food supplement, appears to be an important metabolic regulator in depleted T cell metabolism.
Norbert Berenzen, Riyadh Rehani, Andrea Ebeling, Marcus Stocker, Motowo Nakajima   +4 more
doaj   +1 more source

Comparative experimental study of 5-ALA and 5-ALA hexyl ester specific activity

Biomedical Photonics, 2018
A comparative experimental study of the specific activity of drugs based on 5-aminolevulinic acid (5-ALA) and its hexyl ester (5-ALA HE) was carried out. Their ability to induce the synthesis of photoactive protoporphyrin IX in the healthy tissues of the
R. I. Yakubovskaya, A. A. Pankratov, E. V. Filonenko, E. A. Lukyanets, V. I. Ivanova-Radkevich, A. A. Trushin, A. D. Kaprin   +6 more
doaj   +1 more source