Results 51 to 60 of about 3,224 (171)
Photoactivable oxobenzopyranoxazole esters of 5-aminolevulinic acid [PDF]
, 2016 Comunicação em painel P51 no 1st European Young Chemists Meeting/ 5th Portuguese Young Chemists Meeting, Guimarães, Portugal, 26-29 Abril 2016.In this communication we report the synthesis of new oxobenzopyranoxazoles 1a,b as photolabile protecting ...
Costa, Susana P. G. +2 more
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Resistance of Cancer Cells to Photodynamic Therapy with 5-aminolevulinic Acid: Role of the ABCG2 Transporter [PDF]
, 2017 Photodynamic Therapy (PDT) is a minimally invasive radiation therapy currently used in treatment of various cancerous and pre-malignant diseases. Photodynamic therapy with 5-aminolaevulinic acid (5-ALA/PDT) induces DNA damage following photoactivation of
Barra, Federica
core +1 more source
Regulatory and retrograde signaling networks in the chlorophyll biosynthetic pathway
Journal of Integrative Plant Biology, Volume 67, Issue 4, Page 887-911, April 2025.This review summarizes the regulatory mechanisms that underlie chlorophyll synthesis, including (1) factors that control the activity and stability of tetrapyrrole biosynthesis enzymes, (2) transcriptional and post‐translational regulation of the tetrapyrrole biosynthesis pathway, and (3) the complex roles of tetrapyrrole‐mediated retrograde signaling ...
Yuhong Li +6 more
wiley +1 more source
Advanced Science, Volume 12, Issue 10, March 13, 2025.BACH1, a basic leucine zipper protein ubiquitously expressed in mammalian tissues, plays a critical role in the regulation of oxidative stress, cell cycle progression, heme homeostasis, and immune responses. It is implicated in cardiovascular diseases, cancer progression, neurodegenerative disorders, and many other diseases.
Xiangxiang Wei +9 more
wiley +1 more source
Molecular breeding of tomato: Advances and challenges
Journal of Integrative Plant Biology, Volume 67, Issue 3, Page 669-721, March 2025.This review explores the evolution of tomato (Solanum lycopersicum) from its Andean origins to a globally cultivated crop, highlighting advancements in molecular breeding. It covers genome sequencing, functional gene identification, and CRISPR/Cas9 applications, addressing challenges in flavor, yield, and other important agrinomic traits, while ...
Minmin Du +11 more
wiley +1 more source
Biochemical and Structural Characterisation of a Bacterial Lactoperoxidase
ChemBioChem, Volume 26, Issue 2, January 14, 2025.This study presents the biochemical and structural characterization of CyanoPOX, a heme‐containing peroxidase from Cyanobacterium sp. TDX16. Expressed in E. coli, the enzyme exhibits properties similar to bovine lactoperoxidase despite low sequence identity.
Ognjen Pećanac +5 more
wiley +1 more source
Innovative Agents for Actinic Keratosis and Nanocarriers Enhancing Skin Penetration [PDF]
, 2010 Actinic keratosis and cutaneous squamous cell carcinoma are of increasing importance with aging and increased ultraviolet light exposure in Western societies. Efficient and well-tolerated therapy is still a matter of concern.
Höltje, H.-D. +3 more
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13C‐Labeling as a Method in Organic Synthesis, Catalysis and Biochemical Applications
Chemistry–Methods, Volume 5, Issue 1, January 2025.Synthesis of 13C‐labeled compounds was a separate field in chemistry. Now, incorporation of 13C label is a useful approach in structure determination of complicated compounds, catalysis, mechanistic investigations, biochemistry and metabolomics. In this review, carbon‐13 labeling was considered as a method in chemistry, providing efficient routes in ...
Konstantin S. Rodygin +3 more
wiley +1 more source
Patterns in evolutionary origins of heme, chlorophyll a and isopentenyl diphosphate biosynthetic pathways suggest non-photosynthetic periods prior to plastid replacements in dinoflagellates [PDF]
, 2018 BackgroundThe ancestral dinoflagellate most likely established a peridinin-containing plastid, which have been inherited in the extant photosynthetic descendants.
Inagaki Yuji +2 more
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Porokeratoses: an update on pathogenesis and treatment
International Journal of Dermatology, Volume 64, Issue 1, Page 62-71, January 2025.Abstract Porokeratoses (PK) are a group of uncommon dermatoses characterized by abnormal epidermal differentiation due to a disorder of the mevalonate metabolic pathway. Several clinical subtypes exist that can be associated with the same patient or affect different patients within a family and could, therefore, be different expressions of one disease.
Konstantinos‐Antonios Kostopoulos‐Kanitakis +1 more
wiley +1 more source