Results 51 to 60 of about 18,317 (178)

Resistance of Cancer Cells to Photodynamic Therapy with 5-aminolevulinic Acid: Role of the ABCG2 Transporter [PDF]

open access: yes, 2017
Photodynamic Therapy (PDT) is a minimally invasive radiation therapy currently used in treatment of various cancerous and pre-malignant diseases. Photodynamic therapy with 5-aminolaevulinic acid (5-ALA/PDT) induces DNA damage following photoactivation of
Barra, Federica
core   +1 more source

Insulin-Like Growth Factor-2 Is Induced Following 5-Aminolevulinic Acid-Mediated Photodynamic Therapy in SW620 Human Colon Cancer Cell Line

open access: yesInternational Journal of Molecular Sciences, 2015
The IGF system is a family of polypeptide growth factors, which plays a significant role in the development and growth of many cells. Dysregulation of insulin-like growth factors and their pathway components has been connected with essential tumor ...
M. Woźniak   +2 more
semanticscholar   +1 more source

The Multifaceted Roles of BACH1 in Disease: Implications for Biological Functions and Therapeutic Applications

open access: yesAdvanced Science, Volume 12, Issue 10, March 13, 2025.
BACH1, a basic leucine zipper protein ubiquitously expressed in mammalian tissues, plays a critical role in the regulation of oxidative stress, cell cycle progression, heme homeostasis, and immune responses. It is implicated in cardiovascular diseases, cancer progression, neurodegenerative disorders, and many other diseases.
Xiangxiang Wei   +9 more
wiley   +1 more source

Molecular breeding of tomato: Advances and challenges

open access: yesJournal of Integrative Plant Biology, Volume 67, Issue 3, Page 669-721, March 2025.
This review explores the evolution of tomato (Solanum lycopersicum) from its Andean origins to a globally cultivated crop, highlighting advancements in molecular breeding. It covers genome sequencing, functional gene identification, and CRISPR/Cas9 applications, addressing challenges in flavor, yield, and other important agrinomic traits, while ...
Minmin Du   +11 more
wiley   +1 more source

The Recurrence and Cosmetic Results After Topical Photodynamic Therapy [PDF]

open access: yes, 2009
Background and Design: Photodynamic therapy (FDT) is a photochemotherapy modality which is used frequently and effectively in the treatment of actinic keratosis, Bowen disease and basal cell carcinomas.
Alican Kazandı   +2 more
core  

Innovative Agents for Actinic Keratosis and Nanocarriers Enhancing Skin Penetration [PDF]

open access: yes, 2010
Actinic keratosis and cutaneous squamous cell carcinoma are of increasing importance with aging and increased ultraviolet light exposure in Western societies. Efficient and well-tolerated therapy is still a matter of concern.
Höltje, H.-D.   +3 more
core   +1 more source

Biochemical and Structural Characterisation of a Bacterial Lactoperoxidase

open access: yesChemBioChem, Volume 26, Issue 2, January 14, 2025.
This study presents the biochemical and structural characterization of CyanoPOX, a heme‐containing peroxidase from Cyanobacterium sp. TDX16. Expressed in E. coli, the enzyme exhibits properties similar to bovine lactoperoxidase despite low sequence identity.
Ognjen Pećanac   +5 more
wiley   +1 more source

Patterns in evolutionary origins of heme, chlorophyll a and isopentenyl diphosphate biosynthetic pathways suggest non-photosynthetic periods prior to plastid replacements in dinoflagellates [PDF]

open access: yes, 2018
BackgroundThe ancestral dinoflagellate most likely established a peridinin-containing plastid, which have been inherited in the extant photosynthetic descendants.
Inagaki Yuji   +2 more
core   +2 more sources

13C‐Labeling as a Method in Organic Synthesis, Catalysis and Biochemical Applications

open access: yesChemistry–Methods, Volume 5, Issue 1, January 2025.
Synthesis of 13C‐labeled compounds was a separate field in chemistry. Now, incorporation of 13C label is a useful approach in structure determination of complicated compounds, catalysis, mechanistic investigations, biochemistry and metabolomics. In this review, carbon‐13 labeling was considered as a method in chemistry, providing efficient routes in ...
Konstantin S. Rodygin   +3 more
wiley   +1 more source

Porokeratoses: an update on pathogenesis and treatment

open access: yesInternational Journal of Dermatology, Volume 64, Issue 1, Page 62-71, January 2025.
Abstract Porokeratoses (PK) are a group of uncommon dermatoses characterized by abnormal epidermal differentiation due to a disorder of the mevalonate metabolic pathway. Several clinical subtypes exist that can be associated with the same patient or affect different patients within a family and could, therefore, be different expressions of one disease.
Konstantinos‐Antonios Kostopoulos‐Kanitakis   +1 more
wiley   +1 more source

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