Enantioselective Synthesis and Photoracemization Studies of (+)-2-Cyclopropyl-7,8-dimethoxy-2H- chromene-5-carboxylic Acid Methyl Ester, an Advanced Intermediate of a Dihydrofolate Reductase ...
Peter Wipf (134666) +1 more
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Biochemical and Structural Characterisation of a Bacterial Lactoperoxidase
This study presents the biochemical and structural characterization of CyanoPOX, a heme‐containing peroxidase from Cyanobacterium sp. TDX16. Expressed in E. coli, the enzyme exhibits properties similar to bovine lactoperoxidase despite low sequence identity.
Ognjen Pećanac +5 more
wiley +1 more source
Biophysical aspects of photodynamic therapy
Photodynamic therapy (PDT) is a multimodality cancer treatment available for the palliation or eradication of systemic and cutaneous malignancies. In this thesis, the application of PDT is for the treatment of non-melanoma skin cancer (NMSC).
Valentine, Ronan
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Synthesis of 1-Methyl-3-oxo-7-oxabicyclo[2.2.1]hept-5-ene-2-carboxylic Acid Methyl Ester
A simple and efficient method for the preparation of 1-methyl-3-oxo-7- oxabicyclo[2.2.1]hept-5-en-2-carboxylic acid methyl ester (1) is described. The first step is a highly regioselective Diels-Alder reaction between 2-methylfuran and methyl-3-bromo ...
Adilson Beatriz +5 more
core +1 more source
Synthesis and characterization of 5-(4-hydroxy-3-methoxy-phenyl)-3,7-dimethyl-5H-thiazolo3,2-apyrimidine-2,6-dicarboxylic acid 2-ethyl ester 6-methyl ester and its 6-ethyl ester 5-naphthalene derivative [PDF]
The compounds 5-(4-hydroxy-3-methoxy-phenyl)-3,7-dimethyl-5H-thiazolo[3,2-a]pyrimidine-2,6-dicarboxylic acid 2-ethyl ester 6-methyl ester (2a) and 3,7-dimethyl-5-naphthalen-1-yl-5H-thiazolo[3,2-a]pyrimidine-2,6-dicarboxylic acid diethyl ester (2b) were ...
Nagarajaiah, H. +4 more
core +1 more source
13C‐Labeling as a Method in Organic Synthesis, Catalysis and Biochemical Applications
Synthesis of 13C‐labeled compounds was a separate field in chemistry. Now, incorporation of 13C label is a useful approach in structure determination of complicated compounds, catalysis, mechanistic investigations, biochemistry and metabolomics. In this review, carbon‐13 labeling was considered as a method in chemistry, providing efficient routes in ...
Konstantin S. Rodygin +3 more
wiley +1 more source
Porokeratoses: an update on pathogenesis and treatment
Abstract Porokeratoses (PK) are a group of uncommon dermatoses characterized by abnormal epidermal differentiation due to a disorder of the mevalonate metabolic pathway. Several clinical subtypes exist that can be associated with the same patient or affect different patients within a family and could, therefore, be different expressions of one disease.
Konstantinos‐Antonios Kostopoulos‐Kanitakis +1 more
wiley +1 more source
Peripheral Metal Complexes: Chlorophyll “Isomers” with Magnesium Bound to the Ring E ß-Keto Ester System [PDF]
Peripheral magnesium complexes of methyl pheophorbides a and b, bacteriomethyl pheophorbide a, bacteriopheophytin a, and protopheophytin a have been prepared and characterized by UV-vis, IR, ‘H NMR, and luminescence spectroscopy.
Scheer, Hugo, Katz, J. J.
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Synthesis and Analytical Characterization of Cyclization Products of 3-Propargyloxy-5-benzyloxy-benzoic Acid Methyl Ester [PDF]
In the context of our ongoing studies on chromane derivatives as inhibitors of the salicylate synthase from M. tuberculosis, we isolated a new, unexpected compound from the cyclization of 3-(propargyloxy)-5-benzyloxy-benzoic acid methyl ester.
Matteo Mori +3 more
core +1 more source
The use of 5-aminolevulinic acid and its esters to induce endogenous porphyrins for the purpose of detection of epithelial cancers is being studied extensively in many centres around the world.
Heng, Paul Wan Sia +5 more
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