Using patient‐derived primary cancer cell models and conventional cell lines with varying levels of epidermal growth factor receptor (EGFR) expression, the protocol for performing tumor‐targeted, activatable photoimmunotherapy (taPIT) has been refined to avoid non‐specific cell death in vitro.
Sudip Timilsina +4 more
wiley +1 more source
We report a family of BODIPY‐perylene charge transfer compounds with and without iodination and/or a mesityl group. The BODIPY derivatives reported show high phototoxicity in both 2D cell cultures and multicellular tumour spheroids, where MB2PI (iodinated BODIPY‐perylene with a mesityl group) was the most phototoxic derivative, indicating that ...
Rhianne C. Curley +4 more
wiley +1 more source
Effects of zinc against mercury toxicity in female rats 12 and 48 hours after HgCl2 exposure [PDF]
This work investigated the toxicity of inorganic mercury and zinc preventive effects in female rats sacrificed 12 or 48 h after HgCl2 exposure. Female Wistar rats were subcutaneously injected with ZnCl2 (27 mg/kg) or saline (0.9 %), and 24 h later they ...
Bizzi, Cezar Augusto +6 more
core +1 more source
New Approaches to Photodynamic Therapy from Type I, II and III to Type IV Using One or More Photons [PDF]
Photodynamic therapy (PDT) is an alternative cancer treatment to conventional surgery, radiotherapy and chemotherapy. It is based on activating a drug with light that triggers the generation of cytotoxic species that promote tumour cell killing.
Bisby, RH +3 more
core +2 more sources
Biomass, chlorophyll and nitrogen content of leaves of two chili pepper varieties (Capsicum annum) in different fertilization treatments [PDF]
Abstrak. Suharja, Sutarno. 2009. Biomassa, kandungan klorofil dan nitrogen daun dua varietas cabai (Capsicum annum) pada berbagai perlakuan pemupukan. Nusantara Bioscience 1: 9-16.
SUHARJA,, SUTARNO,
core
A novel light source with tuneable uniformity of light distribution for artificial daylight photodynamic therapy [PDF]
This project was supported by the University of St. Andrews through the Science and Technology Facilities Council (STFC) Impact Accelerator Award (IAA) and by the Laser Research and Therapy Fund (registered charity SC030850). P O’M is funded by Medi-lase
Brown, C. Tom A. +5 more
core +3 more sources
Duramycin-porphyrin conjugates for targeting of tumour cells using photodynamic therapy [PDF]
Duramycin, through binding with phosphatidylethanolamine (PE), has been shown to be a selective molecular probe for the targeting and imaging of cancer cells.
Boyle, RW +6 more
core +3 more sources
Like a bolt from the blue : phthalocyanines in biomedical optics [PDF]
The purpose of this review is to compile preclinical and clinical results on phthalocyanines (Pcs) as photosensitizers (PS) for Photodynamic Therapy (PDT) and contrast agents for fluorescence imaging.
Ackroyd +171 more
core +4 more sources
Photolytic release of bioactive carboxylic acids from fused pyran conjugates [PDF]
New ester cages bearing the coumarin (2H-benzopyran-2-one) skeleton with extended π-systems as phototriggers, for glycine and β-alanine, as models of carboxylic acid bifunctional molecules with biological relevance, were evaluated under photolysis ...
Conceição, Rafaela +3 more
core +1 more source
Fotodinamička inaktivacija patogene bakterije Listeria monocytogenes u hrani [PDF]
The aim of this study is to examine the possibility to inactivate food pathogen Listeria monocytogenes by nonthermal antimicrobial treatment – photosensitization. L.
Egle Paskeviciute +2 more
core +1 more source

