Changes in immunohistochemical levels and subcellular localization after therapy and correlation and colocalization with CD68 suggest a pathogenetic role of Hsp60 in ulcerative colitis. [PDF]
In an earlier work, the role of heat shock protein (Hsp60) in the pathogenesis of ulcerative colitis (UC) was suggested by its significant increase in the pathological mucosa parallel with an increase in inflammatory cells.
ACCOMANDO, Salvatore +16 more
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2-Hydroxy-5-{[(E)-4-methoxybenzylidene]azaniumyl}benzoate
In the title zwitterion, C15H13NO4, obtained from the condensation of 5-aminosalicylic acid and 4-methoxybenzaldehyde, the 4-hydoxyanilinic group of the 5-aminosalicylic acid moiety and the 4-methoxybenzaldehyde moiety are twisted with respect to one ...
Shahbaz Ahmad +3 more
doaj +1 more source
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor +4 more
wiley +1 more source
A randomised phase I study of etrolizumab (rhuMAb β7) in moderate to severe ulcerative colitis. [PDF]
ObjectiveEtrolizumab (rhuMAb β7, anti-β7, PRO145223) is a humanised monoclonal antibody targeting the β7 subunit of the heterodimeric integrins α4β7 and αEβ7, which are implicated in leucocyte migration and retention in ulcerative colitis (UC).
Baumgart, Daniel C +16 more
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ABSTRACT Extracellular vesicles (EVs) are nanoscale mediators of intercellular communication with diverse molecular cargoes that reflect their cell of origin. Advances in isolation, detection, and single‐particle analytics have revealed increasing molecular and functional heterogeneity, while exposing limitations in how EV identity and activity are ...
David J. Lundy +8 more
wiley +1 more source
Short-Course Chemotherapy for Tuberculosis [PDF]
Annotated and edite transcript of a Witness Seminar held on 3 February 2004. Introduction by Dr Linda Bryder, University of Auckland.First published by the Wellcome Trust Centre for the History of Medicine at UCL, 2005. ©The Trustee of the Wellcome Trust,
Christie, DA, Tansey, EM
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Therapeutic and toxic blood concentrations of nearly 1,000 drugs and other xenobiotics [PDF]
Introduction: In order to assess the significance of drug levels measured in intensive care medicine, clinical and forensic toxicology, as well as for therapeutic drug monitoring, it is essential that a comprehensive collection of data is readily ...
Andresen, Hilke +3 more
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Antioxidant effect of 5-amino salicylic acid on copper-mediated LDL oxidation
The antioxidant effect of 5-Aminosalicylic acid (5-ASA) on copper-mediated LDL oxidation was followed either by the emitted chemiluminiscence (CL) or by UV-vis spectroscopy. 5-ASA addition extends the lag phase in a concentration-dependent manner without
CAMILO LÓPEZ-ALARCÓN +2 more
doaj
Lupus-Like Syndrome Caused by 5-Aminosalicylic Acid in Patients with Inflammatory Bowel Disease
BACKGROUND: Although 5-aminosalicylic acid (5-ASA) preparations used to treat inflammatory bowel disease are reported to have fewer side effects than sulphasalazine, increased clinical use of these compounds has resulted in increased reports of ...
Andrew W Kirkpatrick +2 more
doaj +1 more source
Microdetermination of urea in urine using p-dimethylaminobenzaldehyde /PDAB/ [PDF]
Adaptation of the p-dimethylaminobenzaldehyde method for determining urea concentration in urine is an improved micromechanical method. Accuracy and precision are satisfactory.
Geiger, P. J.
core +1 more source

