Results 61 to 70 of about 13,247 (180)

Severe Ulcerative Colitis With Cytomegalovirus Colitis Treated by Early Surgery: A Case Report

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Acute severe ulcerative colitis complicated by cytomegalovirus infection requires individualized management, and timely surgical intervention should be considered in carefully selected high‐risk patients who are unlikely to benefit from further medical therapy.
Hiroyuki Fujimura, Atsushi Goto, Takenaka Kazuyuki, Hiroshi Itoh, Taro Takami   +4 more
wiley   +1 more source

Oral Health of Patients With Inflammatory Bowel Disease—A Cross‐Sectional Survey in Austria

Clinical and Experimental Dental Research, Volume 12, Issue 4, August 2026.
ABSTRACT Objective This cross‐sectional survey aimed to assess oral health in patients with inflammatory bowel diseases (IBD) living in Austria. Methods Data collection was conducted with an online questionnaire, including when possible validated tools, covering general medical history, socioeconomic factors, IBD‐related parameters, and various oral ...
Kristina Bertl, Arghavan Yari, Anna Riener, Johan Burisch, Nikolaos Pandis, Hady Haririan, Andreas Stavropoulos   +6 more
wiley   +1 more source

Cod Skin Collagen Peptides Alleviate Ulcerative Colitis by Regulating Gut Microbiota to Inhibit NLRP3 Inflammasome Activation

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
CP suppresses NLRP3 inflammasome activation through modulation of the gut microbiota, thereby exerting protective effects against ulcerative colitis. ABSTRACT Enteral nutrition is an important intervention for ulcerative colitis, and collagen can improve immune responses and repair the intestinal barrier.
Longyi Piao, Jiaqi Huo, Yanru Dong, Shuxia Cao, Xiangdan Li, Dongyuan Xu, Xianglan Li, Lan Liu   +7 more
wiley   +1 more source

Safety, Pharmacokinetics, Food effect, and Pharmacodynamics of AJM347, a Selective α4β7 Integrin Antagonist: A First‐in‐Human Single‐ and Multiple‐Ascending Dose Study in Healthy Male Volunteers

The Journal of Clinical Pharmacology, Volume 66, Issue 8, August 2026.
Abstract This first‐in‐human study evaluated the safety, pharmacokinetics (PK), food effect, and pharmacodynamics (PD) of AJM347, a novel orally active, selective α4β7 integrin antagonist, in healthy Caucasian and Japanese adult males. The study consisted of three parts.
Tetsuya Koyama, Tatsunori Seki
wiley   +1 more source

The Burden of Viral Respiratory Infections in Immunosuppressed Inflammatory Bowel Disease Patients

JGH Open, Volume 10, Issue 8, August 2026.
ABSTRACT Background and Aim Due to the increasing immunosuppressant use in inflammatory bowel disease (IBD) and the risk of serious infections, this study investigates the prevalence and risk factors of respiratory pathogen detection in this population to improve patient care.
D. Huynh, E. Khoo, A. Shanmuga Anandan, J. Begun   +3 more
wiley   +1 more source

MetF‐Dependent Methionine Biosynthesis Is Required for Mycobacterium tuberculosis Survival and In Vivo Persistence

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
MetF is essential for both in vitro and in vivo growth of Mycobacterium tuberculosis, whereas MetE, previously considered essential in vitro, is dispensable in vivo. Given the importance of methionine and folate metabolism as drug targets, MetF represents a promising candidate, highlighting the need for in vivo validation.
Ikue Tosa, Tomoki Kitahara, Katsuki Takebe, Masaaki Nakayama, Yuko Ito, Akihito Nishiyama, Shintaro Seto, Hotaka Kawai, Hiharu Inoue, Yuki Fukada, Yuki Nishiya, Hitoshi Nagatsuka, Takayuki Wada, Manabu Ato, Sohkichi Matsumoto, Naoya Ohara   +15 more
wiley   +1 more source

Five‐Year Outcomes and Disease Trajectories in Moderate‐to‐Severe Ulcerative Colitis: A Korean Multicenter Inception Cohort

Journal of Gastroenterology and Hepatology, Volume 41, Issue 8, Page 2338-2348, August 2026.
ABSTRACT Background and Aim The incidence of ulcerative colitis (UC) has been increasing in Asia. Comprehensive data on the long‐term course of moderate‐to‐severe UC remain scarce. This study investigated the clinical outcomes and factors associated with a disabling disease course in Korean patients with moderate‐to‐severe UC.
Byong Duk Ye, Hyo Jong Kim, Dong Il Park, Young Sook Park, Kang‐Moon Lee, Jong Pil Im, Sung‐Ae Jung, Yoon Tae Jeen, Jae Myung Cha, Jae Hee Cheon, Sung Noh Hong, Youngdoe Kim, Jong Min Choi, YoungJa Lee, Chang Kyun Lee   +14 more
wiley   +1 more source

Flavonoids and 5-Aminosalicylic Acid Inhibit the Formation of Neutrophil Extracellular Traps

Mediators of Inflammation, 2013
Neutrophil extracellular traps (NETs) have been suggested to play a pathophysiological role in several autoimmune diseases. Since NET-formation in response to several biological and chemical stimuli is mostly ROS dependent, in theory any substance that ...
Tina Kirchner, Eva Hermann, Sonja Möller, Matthias Klinger, Werner Solbach, Tamás Laskay, Martina Behnen   +6 more
doaj   +1 more source

Effect of intra-abdominally administered mesalazine (5-aminosalicylic acid) in experimental peritonitis

İstanbul Kuzey Klinikleri, 2018
INTRODUCTION[|]In this study,the effect of mesalazine was studied on TNF alpha IL-1 beta, IL-6, and C-reactive protein (CRP) levels and inflammatory changes in rat lungs with experimental peritonitis.[¤]METHODS[|]In total, 24 male Sprague–Dawley rats ...
Aziz Şener, Alper Şahbaz, Leyla Türker Şener, Merva Soluk Tekkeşin, Bülent Kaya   +4 more
doaj   +1 more source

Efficacy of mesalazine at ulcerative colitis with nutritional failure

Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2015
Aim of investigation. To specify relation between trophological status, severity of relapse of ulcerative colitis (UC) and efficacy of 5-aminosalicylic acid (5-ASA) for achievement of clinical remission.Summary.
A. V. Korolyov, O. S. Shifrin, O. Z. Okhlobystina, L. N. Androsova, Yu. O. Sidorina   +4 more
doaj