Results 201 to 210 of about 11,853,684 (309)

A Word of Caution: Watch and Wait in the Total Mesorectal Excision Era

ANZ Journal of Surgery, EarlyView.
Among 573 patients undergoing long‐course neoadjuvant chemoradiotherapy and total mesorectal excision between 2006 and 2020, five‐year overall survival was 85.7%. Local recurrence was 3.4% and metastatic recurrence was 16.5%. Pathological stage and tumour regression grade stratified long‐term outcomes, providing regional benchmarks for evaluating organ‐
K. Broughton, R. Cohen, A. Armanios, S. Jamin, E. Eguare, H. Yoo, G. Lim, E. Maclean, M. Teoh, M. Nyandoro, M. H. Wallace, J. Ryan   +11 more
wiley   +1 more source

Plasma 5-Fluorouracil Exposure, Clinical Outcomes, and Therapeutic Drug Monitoring in Advanced Colorectal Cancer. [PDF]

Cancers (Basel)
Sakuyama N, Nagayasu K, Abe Y, Ochiai T, Shibasaki F.   +4 more
europepmc   +1 more source

Chemotherapy resistance and risk stratification in gestational trophoblastic neoplasia: A systematic review and network meta‐analysis

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Higher pretreatment β‐hCG, greater tumor burden, higher FIGO stage/score, and choriocarcinoma were associated with higher chemoresistance risk in gestational trophoblastic neoplasia. In exploratory network analyses, etoposide‐containing regimens showed lower predicted chemoresistance.
Ying‐Ying Xue, Xin‐Yue Yang, Fang‐Yu Chen, Hui‐Ting Yang, Chao Zhang, Jin‐Zhu Yan, Shi‐Shi Wu, Long Wang   +7 more
wiley   +1 more source

5-Fluorouracil-induced vasospastic angina.

Annals of Saudi Medicine, 2005
Ayyildiz Orhan, Karabulut Aziz, Isikdogan Abdurrahman, Cakir Omer, Dursun Mehmet   +4 more
doaj  

Retraction Note: Enhanced antitumor efficacy in colon cancer using EGF functionalized PLGA nanoparticles loaded with 5-Fluorouracil and perfluorocarbon. [PDF]

BMC Cancer
Wu P, Zhou Q, Zhu H, Zhuang Y, Bao J.
europepmc   +1 more source

Longitudinal changes in bleb morphology following the PAUL Glaucoma Implant visualized using ultrasonography

Acta Ophthalmologica, EarlyView.
Abstract Purpose To evaluate bleb morphology longitudinally using sonography following glaucoma drainage device (GDD) surgery. Methods Prospective observational cohort study conducted from January 2022 to March 2024, with follow‐up up to 12 months postoperatively. Bleb morphology, including superior and inferior bleb height, transverse and longitudinal
Constance Liegl, Benjamin Aretz, Leonie Bourauel, Pascal Schipper, Carolin Deubel, Lilli Joussen, Michael Petrak, Frank G. Holz, Raffael Liegl, Karl Mercieca   +9 more
wiley   +1 more source

Efficacy of Early Pegfilgrastim Administration during Preoperative Docetaxel, Cisplatin, and 5-Fluorouracil Therapy in Esophageal Cancer. [PDF]

JMA J
Takei M, Tsujimoto H, Ide A, Kariya R, Uehata N, Suzuki T, Fujishima S, Kouzu K, Yaguchi Y, Ueno H.   +9 more
europepmc   +1 more source

Proliferative vitreoretinopathy: An integrative, multi‐pathway perspective on pathogenesis and therapy

Acta Ophthalmologica, EarlyView.
Abstract Proliferative vitreoretinopathy (PVR) remains the principal biological cause of failed retinal detachment repair. Classical pathogenic models centred on retinal pigment epithelium (RPE) dispersion, retinal injury responses or compartment‐restricted mechanisms do not fully explain the heterogeneity, biomechanical behaviour and clinical ...
Koen A. van Overdam, J. Sebag
wiley   +1 more source

Isoquercitrin Alleviates 5-Fluorouracil-Induced Intestinal Mucositis in Mice by Modulating Inflammation and Oxidative Stress. [PDF]

Chem Biodivers
Fideles LS, Campelo MDS, Neto JFC, Martins CDS, Barreto JEF, Vieira ÍGP, Ricardo NMPS, Cerqueira GS, Ribeiro MENP.   +8 more
europepmc   +1 more source

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source