MSCs exert anti‐inflammatory, anti‐fibrotic and regenerative effects in pulmonary fibrosis. MSC‐derived exosomes reproduce many therapeutic benefits of parental MSCs. Preconditioning and genetic modification improve MSC therapeutic performance. Current preclinical and clinical evidence supports the translational potential of MSC‐based therapies ...
Hajar Nasiri +8 more
wiley +1 more source
Utilizing the VISIA Camera for Analyzing 5-Fluorouracil Treatment Efficacy for Actinic Keratosis. [PDF]
Woolhiser E +4 more
europepmc +1 more source
Impact of Infratemporal Fossa Clearance on Survival in Advanced Buccal Mucosa Cancers
ABSTRACT Introduction Buccal mucosa cancers are the most prevalent oral cavity cancers in South Asia, often attributed to widespread tobacco use. The current NCCN guidelines generally advise against primary surgery for locally very advanced (cT4b) buccal cancers involving the masticatory space and infratemporal fossa (ITF).
Sudhir Nair +11 more
wiley +1 more source
Intralesional triamcinolone versus 5-fluorouracil for keloids and hypertrophic scars: A randomized comparative clinical study. [PDF]
Sharma A +6 more
europepmc +1 more source
De novo or Salvage? Nucleotide Availability as a Driver of Bacterial Adaptation and Virulence
Bacterial pathogens survive in different host environments by switching between making nucleotides by de novo synthesis and scavenging them from the host. This flexibility supports growth and virulence making nucleotide metabolism an attractive therapeutic target.
Riya Joshi +2 more
wiley +1 more source
Recalcitrant Hailey-Hailey disease in a 55-year-old Filipino woman successfully treated with 5-fluorouracil and excimer lamp phototherapy: A case report. [PDF]
Pabico AJW +3 more
europepmc +1 more source
What's new? While the effectiveness of systemic anticancer therapy is well documented, it commonly causes severe toxicity. This study of the 467 systemic anticancer therapy agents currently approved globally for clinical and/or research purposes found that peripheral neurotoxicity is associated with 45% of classical chemotherapies, 21% of targeted ...
Cassie Higgins +3 more
wiley +1 more source
Enhancing 5-fluorouracil efficacy in colorectal cancer by inhibiting glutathione antioxidant mechanisms with an xCT inhibitor. [PDF]
Malcanlı S +4 more
europepmc +1 more source
What's new? Esophageal adenocarcinoma (EAC) is an aggressive cancer with poor survival and variable response to perioperative chemotherapy. Although histopathological features correlate with outcomes, the relationship specifically between adherens junction (AJ) protein expression and treatment response in EAC remains uncertain.
Bastian Grothey +8 more
wiley +1 more source
5-Fluorouracil-Induced Microvascular Vasospasm Diagnosed by Coronary Functional Testing. [PDF]
Rana R +4 more
europepmc +1 more source

