What's new? Adaptive immune responses are typically limited in pancreatic ductal adenocarcinoma, resulting in minimal efficacy of immune checkpoint inhibitors. Tumor Treating Fields (TTFields) therapy, which uses low‐intensity intermediate‐frequency electric fields to disrupt cancer cell processes, has been approved for certain cancers.
Tal Kan +21 more
wiley +1 more source
5-Fluorouracil-induced vasospastic angina.
Ayyildiz Orhan +4 more
doaj
5-Fluorouracil-induced Reversible Encephalopathy. [PDF]
Varun TM, Prasun P, Amte D.
europepmc +1 more source
Figure 1 visually summarizes the core biological functions and therapeutic potential of the HGF/c‐Met signaling axis. Abstract Hepatocyte growth factor (HGF) is a multifunctional cytokine that activates the tyrosine kinase activity of its specific receptor, c‐Met (mesenchymal–epithelial transition factor).
Hongqin Sun +7 more
wiley +1 more source
DFT Calculations on Electronic, Thermochemical and Vibrational Properties of Se<sub>6</sub> Selenium Clusters as 5-Fluorouracil Drug Delivery System. [PDF]
Solano-González LI +4 more
europepmc +1 more source
Mesna in Otologic Surgery: Efficacy and Safety—A Scoping Review
PRISMA flow diagram indicating the process of systematic inclusion and exclusion of articles. ABSTRACT Objective Mesna (Sodium 2‐mercaptoethanesulfonate) is widely used as a mucolytic agent and uroprotective agent. Recently, its disulfide bond‐breaking property has been applied in otologic surgery to facilitate safer dissection of cholesteatoma and ...
Kevork H. Atamian +4 more
wiley +1 more source
Synergistic Effect of 5-Fluorouracil and Amphotericin B in Murine Paracoccidioidomycosis: Immune Modulation and Enhanced Fungal Clearance. [PDF]
Franco FN +7 more
europepmc +1 more source
The Role of N6‐Methyladenosine Modification in Health and Disease
N6‐methyladenosine (m6A) is the most prevalent internal RNA modification in eukaryotes, acting as a pivotal epitranscriptomic regulator of RNA metabolism. This modification plays a dual role: it maintains physiological homeostasis under normal conditions but drives disease progression when dysregulated.
Linghuan Li +6 more
wiley +1 more source
<i>Larimichthys crocea</i> Swim Bladder Polysaccharides Attenuate 5-Fluorouracil-Induced Intestinal Injury by Modulating the Gut-Metabolic Axis. [PDF]
Zhao S +11 more
europepmc +1 more source
The Dual Role of Autophagy in Cancer: Mechanisms and Therapeutic Strategies
Autophagy is a conserved cellular process degrading dysfunctional organelles and protein aggregates to maintain cell homeostasis, and it exhibits context‐dependent duality in cancer. Autophagy functions as a critical tumor‐suppressive mechanism by preventing DNA damage and mutation during tumor initiation.
Xiang‐Zheng Gao +4 more
wiley +1 more source

