Results 231 to 240 of about 8,527,959 (316)

Pyruvate Kinase M2 Mediates Apigenin‐Induced Energy Crisis and Apoptosis in Colon Cancer Cells

Food Frontiers, Volume 7, Issue 4, July 2026.
Apigenin, a dietary flavonoid with low toxicity, induces profound bioenergetic collapse in colon cancer cells by downregulating PKM2. This metabolic crisis, characterized by suppressed glycolysis and mitochondrial dysfunction, ultimately triggers robust apoptosis.
Ke Zhang, Xingtao Zhou, Xujie Wang, Mingyong Xie   +3 more
wiley   +1 more source

Synthesis and Evaluation of Carbon Black-Containing Hydrogels for the Adsorption of 5-Fluorouracil. [PDF]

Gels
Sekiguchi-Arai R, Yamazaki Y, Sato T, Noma N, Oka K, Iwasaki M.   +5 more
europepmc   +1 more source

Apple Pomace Pectin for Gastroprotective Nutraceutical Delivery: Structure–Function Relationships and Nano/Microencapsulation Strategies for Gastric Ulcer Management

Food Frontiers, Volume 7, Issue 4, July 2026.
Apple pomace pectin is explored as a sustainable and multifunctional biomaterial for gastric ulcer management. Its unique structural features confer mucoadhesive, anti‐inflammatory, antioxidant, and anti‐Helicobacter pylori activities while enabling nano/microencapsulation of therapeutic agents.
Akash Dhiman, Shefali Arora, Parteek Prasher, Sukanya Chhetri, Pankaj Bhandari, William N. Setzer, Javad Sharifi‐Rad   +6 more
wiley   +1 more source

A case of corneal epithelial downgrowth after penetrating keratoplasty treated by intracameral 5-fluorouracil injection and mitomycin C. [PDF]

GMS Ophthalmol Cases
Wat NH, Siu GDJ, Wu MS, Wong L.
europepmc   +1 more source

Immune, molecular and genetic profiles of gastric signet ring cell carcinoma: Recent progress and future challenges

International Journal of Cancer, Volume 159, Issue 1, Page 11-29, 1 July 2026.
Abstract Gastric signet ring cell carcinoma (GSRCC) is a special type of gastric cancer common in young women. Diffuse gastric cancer (DGC) begins with intramucosal lesions comprising differentiated GSRCC cells. Genetically, GSRCC and DGC are clonally identical, with their morphology influenced by extracellular Wnt signaling.
Qian Wang, Shuai Zhou, Xiongchao Fang, Xianli He, Gang Wang, Nan Wang   +5 more
wiley   +1 more source

Efficacy and Safety Assessment of 5-Fluorouracil, Irinotecan and Oxaliplatin-Loaded Implants in Mouse and Pig Models for Pancreatic Cancer Therapy. [PDF]

Adv Mater
Wade SJ, Kumar AA, Nitschke SO, Joyce P, Minaei E, Reuter SE, Penney C, Warren H, Shepherd R, Dinoro JN, Wallace GG, Dosseto A, Ansar S, Islam N, Lochhead A, Sharbeen G, Phillips PA, Aghmesheh M, Hawthorne WJ, Vine-Perrow KL.   +19 more
europepmc   +1 more source

Safety and Efficacy of a Sandwich Total Neoadjuvant Therapy Strategy for Low‐Risk Distal Locally Advanced Rectal Cancer: Results From the TESS Phase II Trial

MedComm, Volume 7, Issue 7, July 2026.
The proposed sandwich total neoadjuvant treatment (TNT) strategy (NeoCT–CRT–NeoCT) represents a safe and effective therapeutic option for carefully selected patients with low‐risk distal locally advanced rectal cancer (LARC). By sequentially integrating induction chemotherapy, concurrent chemoradiotherapy, and consolidation chemotherapy, this approach ...
Shuang Liu, GuangZhao Lv, GeYu Xu, XiaoZhong Wang, YeZhong Zhuang, ShouMin Bai, HaiNa Yu, XiaoJun Wu, YiJing Ye, HuiLong Luo, ShuoYu Xu, QiaoXuan Wang, Hui Chang, PeiQiang Cai, ZhiZhong Pan, YuanHong Gao, Gong Chen, WeiWei Xiao   +17 more
wiley   +1 more source

A Prebiotic and Panthenol-Containing Repair Balm Improves Tolerability of Topical 5-Fluorouracil Field Therapy for Actinic Keratoses: A Randomised Controlled Trial. [PDF]

Dermatol Ther (Heidelb)
Tseng A, Yu R, Brown S, Muller N, Tan SX, Roy E, Nguyen S, Kerob D, Khosrotehrani K.   +8 more
europepmc   +1 more source

Intratumoral Microbiota in Tumor: Current Understandings and Future Perspectives

MedComm, Volume 7, Issue 7, July 2026.
Intratumoral bacteria are emerging as active regulators of cancer evolution rather than bystanders. This review outlines how tumor‐resident microbes drive tumor initiation and growth by inducing genomic instability, epigenetic reprogramming, oncogenic signaling, and chronic inflammation, while promoting metastatic spread via invasion, angiogenesis ...
Jiawei Chen, Yupan Bai, Lu Shen, Jiacheng Ying, Jie Xu, Jiayin Tang, Yujie Bao   +6 more
wiley   +1 more source